Zobrazeno 1 - 10
of 5 222
pro vyhledávání: '"RA, retinoic acid"'
Publikováno v:
The Journal of Nutritional Biochemistry. 9:676-681
All- trans retinoyl-β-glucuronide, a prominent water-soluble metabolite of all- trans retinoic acid (RA) in animals, is formed by the enzymic transfer of the glucuronyl moiety of uridine diphosphoglucuronic acid to RA. Uridine diphosphoglucuronic ac
Autor:
Magrassi, Lorenzo1,2 (AUTHOR) lorenzo.magrassi@unipv.it, Pinton, Giulia3 (AUTHOR) giulia.pinton@uniupo.it, Luzzi, Sabino1 (AUTHOR) andrea.scravaglieri01@universitadipavia.it, Comincini, Sergio4 (AUTHOR) sergio.comincini@unipv.it, Scravaglieri, Andrea1 (AUTHOR), Gigliotti, Valentina3 (AUTHOR) valentina.gigliotti@uniupo.it, Bernardoni, Bianca Laura5 (AUTHOR) bianca.bernardoni@phd.unipi.it, D'Agostino, Ilaria5 (AUTHOR) ilaria.dagostino@unipi.it, Juretich, Francesca3 (AUTHOR) silvia.garavaglia@uniupo.it, La Motta, Concettina5 (AUTHOR) concettina.lamotta@unipi.it, Garavaglia, Silvia3 (AUTHOR)
Publikováno v:
Cancers. Jul2024, Vol. 16 Issue 13, p2397. 18p.
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 309-321 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of subst
Autor:
Gemma Navarro, Alvaro Lladser, Javier Campos, Alexandra Espinoza, Francisco Contreras, Carolina Prado, Iu Raïch, Rodrigo Pacheco, Rafael Franco, Francisco Osorio-Barrios, Ernesto Lopez, Valentina Ugalde
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 489-506 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and aims: CD4+ T cells constitute central players in inflammatory bowel diseases (IBDs), driving inflammation in the gut mucosa. Current evidence indicates that CCR9 and the integrin α4β7 are necessary and sufficient to imprint colonic h
Publikováno v:
The Journal of Biological Chemistry
Previous studies suggested that cancer cells resemble neural stem/progenitor cells in regulatory network, tumorigenicity, and differentiation potential, and that neural stemness might represent the ground or basal state of differentiation and tumorig
Autor:
Kenji Kamimoto, Samantha A. Morris, Brad W. Warner, Cathleen M. Courtney, Wenjun Kong, William H. Goo, Sarah E. Waye, Kristen M. Seiler, Adam Bajinting, Jun Guo, Emily J. Onufer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Background & Aims The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or “adapt”; the capacity of SI epithelium to
Publikováno v:
Pharmacology & Therapeutics
Individuals differ substantially in their response to pharmacological treatment. Personalized medicine aspires to embrace these inter-individual differences and customize therapy by taking a wealth of patient-specific data into account. Pharmacogenom
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 220-236 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 220-236 (2019)
Obesity is increasing in an alarming rate worldwide, which causes higher risks of some diseases, such as type 2 diabetes, cardiovascular diseases, and cancer. Current therapeutic approaches, either pancreatic lipase inhibitors or appetite suppressors
Autor:
Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz
Publikováno v:
Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Modelling cell infection in-a-dish can represent a useful tool to understand the susceptibility of different cell types towards severe acute respiratory coronavirus-2 (SARS-CoV-2) and to decipher its neurotropism. In this perspective, retinoic acid (
Autor:
Lauren A. Hauser, Marek Napierala, Amanda Clark, Jennifer M. Farmer, Kimal Rajapakshe, David A. Lynch, Peining Xu, Clementina Mesaros, Dean P. Edwards, Yu-Yun Chen, Ian A. Blair, Shixia Huang, Cristian Coarfa, Jill S. Napierala
Publikováno v:
Molecular & Cellular Proteomics : MCP
Identifying biomarkers is important for assessment of disease progression, prediction of symptom development, and determination of treatment effectiveness. While unbiased analyses of differential gene expression using next-generation sequencing metho