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pro vyhledávání: '"R.W. Newman"'
Akademický článek
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Autor:
U. Dunleavy, Diane Major, Philip D. Minor, Othmar G. Engelhardt, Kate Guilfoyle, John Wood, Rebecca Penn, Ruth Harvey, Sarah Skeldon, Jun X. Wheeler, R.W. Newman, Claire Storey, Chantal Edge
Publikováno v:
Vaccine. 36(29)
The current gold-standard potency test for inactivated influenza vaccines is the single radial immunodiffusion (SRD) assay. A number of alternative potency tests for inactivated influenza vaccines have been proposed in recent years. Evaluation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff83ed1f64ebc29964715c2d75b5a53
https://pubmed.ncbi.nlm.nih.gov/29895503
https://pubmed.ncbi.nlm.nih.gov/29895503
Autor:
Michael Pfleiderer, Britta Neumann, Chantal Wallis, Nina Alex, John Wood, Ralf Wagner, Joanna Hammann, R.W. Newman, Constanze Göpfert
Publikováno v:
Vaccine. 30:4113-4122
Haemagglutination-inhibition (HI) and virus neutralisation (VN) assays are routinely applied to evaluate influenza vaccine immunogenicity for regulatory approval. Despite their frequent use both assays are currently only poorly standardised causing c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea81cd17fb10705aa670235e9d91cbc4
https://doi.org/10.1016/j.vaccine.2012.02.077
https://doi.org/10.1016/j.vaccine.2012.02.077
Autor:
Jessica A. Belser, Kortney M. Gustin, Irina Isakova, Taronna R. Maines, Othmar G. Engelhardt, Barbara A. Pokorny, Jeanmarie Silverman, Olga Zoueva, Doris Bucher, Eduardo O’Neill, R.W. Newman, Erin E. Verity, Jianhua Le, Nancy J. Cox, Rachel E. Johnson, James S. Robertson, Sarah Roseby, Sarina Camuglia, Xing Li, Rebecca Collin, Zhengshi Lin, Zhiping Ye, Terrence M. Tumpey, Ruben O. Donis, Chantal Wallis, Kate Guilfoyle, Catherine Agius, Xiyan Xu, Charles T. Davis, Carolyn Nicolson, Anne Curtis, Ramanunninair Manojkumar, Chi Ong, John Wood, Jacqueline M. Katz, Hang Xie, Diane Major, Amanda Balish, Steven Rockman, Ruth Harvey, Peter Schoofs, Rene Devis, Alexander Klimov, Pierre Rivailler, Zhu Guo, Aleksandr S. Lipatov, Li-Mei Chen
Publikováno v:
Vaccine. 29:1836-1843
Wild type human influenza viruses do not usually grow well in embryonated hens' eggs, the substrate of choice for the production of inactivated influenza vaccine, and vaccine viruses need to be developed specifically for this purpose. In the event of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa35825cd7285fc112179c50f42a7420
https://doi.org/10.1016/j.vaccine.2010.12.044
https://doi.org/10.1016/j.vaccine.2010.12.044
Autor:
Sally Batham, Robert Mischler, Maria Zambon, J.M. Klap, Iain Stephenson, Catherine Thompson, R.W. Newman, John Wood, Karl G. Nicholson
Publikováno v:
Vaccine. 28:171-178
Avian influenza H9N2 viruses are considered as a pandemic threat. We assessed the safety and immunogenicity of fourteen H9N2 vaccine formulations. A randomized, phase I trial was done in 353 adults, aged 18-82 years. Subjects received two doses of A/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f8d78188085f6567dc3f0074e0fb63
https://doi.org/10.1016/j.vaccine.2009.09.103
https://doi.org/10.1016/j.vaccine.2009.09.103
Autor:
R.W. Newman, Diane Major, Alan Heath, Iain Stephenson, Jacqueline M. Katz, Maria Zambon, Katja Hoschler, Jerry P. Weir, Wang Junzi, John Wood
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 8, Pp 1250-1259 (2009)
Emerging Infectious Diseases
Emerging Infectious Diseases
Results for clade 1 viruses were more consistent among laboratories when a standard antibody was used.
Hemagglutination-inhibition (HI) and neutralization are used to evaluate vaccines against influenza virus A (H5N1); however, poor standardizat
Hemagglutination-inhibition (HI) and neutralization are used to evaluate vaccines against influenza virus A (H5N1); however, poor standardizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969d3887d1a2527351d47ee9a1ed5ffc
https://wwwnc.cdc.gov/eid/article/15/8/08-1754_article
https://wwwnc.cdc.gov/eid/article/15/8/08-1754_article
Publikováno v:
Medical Microbiology and Immunology. 191:197-201
During normal interpandemic influenza seasons, immune responses to vaccines are quite predictable and meet the licensing criteria of the European Union (EU) Committee for Proprietary Medicinal Products (CPMP). In a pandemic situation, large sections,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fd68c6c31ad01acf530b252dcd11a6
https://doi.org/10.1007/s00430-002-0146-x
https://doi.org/10.1007/s00430-002-0146-x
Autor:
M. Zambon, J. M. Wood, Karl G. Nicholson, R.W. Newman, G. C. Schild, U. Dunleavy, Diane Major, James S. Robertson, D. Melzack, R. Hinton
Publikováno v:
International Congress Series. 1219:751-759
In the event of an influenza pandemic, there will be an urgent need for a vaccine. The human infections with influenza A (H5N1) and A (H9N2) viruses served as pandemic warnings and initiated worldwide efforts to develop suitable vaccines. This was no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52cd9d4370d5297993ba56abdc932d70
https://doi.org/10.1016/s0531-5131(01)00385-5
https://doi.org/10.1016/s0531-5131(01)00385-5
Autor:
D. Melzack, Karl G. Nicholson, J. M. Wood, Diane Major, Maria Zambon, Audino Podda, R.W. Newman
Publikováno v:
International Congress Series. 1219:761-766
Background: It has been recognised that the haemagglutination–inhibition (HI) test is not sufficiently sensitive to detect human antibody to H5N1 influenza virus and alternative serological tests are needed. A modified single radial haemolysis (SRH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b000f99c617a1cf6f3176c2f4e74574
https://doi.org/10.1016/s0531-5131(01)00410-1
https://doi.org/10.1016/s0531-5131(01)00410-1
Publikováno v:
International Congress Series. 1219:789-794
Background : Following the emergence of H9N2 influenza virus in humans it was important to develop vaccines. Protection studies were performed in mice to assess influenza virus strains for their potential as vaccine strains and to evaluate H9N2 influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac40166446b84df03de32d7a7aa26ab3
https://doi.org/10.1016/s0531-5131(01)00357-0
https://doi.org/10.1016/s0531-5131(01)00357-0