Zobrazeno 1 - 10
of 89
pro vyhledávání: '"R.T. Mulcahy"'
Publikováno v:
Biochemical and Biophysical Research Communications. 206:584-589
We have cloned and sequenced a full length cDNA for the light subunit of human liver γ-glutamylcysteine synthetase (GCS1). The GCS1 cDNA consists of 1628 bp, containing an open reading frame of 822 bp which encodes a protein of 274 amino acids havin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313eff19ed8e464d19776f4bff4dcf96
https://doi.org/10.1006/bbrc.1995.1083
https://doi.org/10.1006/bbrc.1995.1083
Publikováno v:
Journal of Medicinal Chemistry. 37:1610-1615
A series of novel nitrobenzyltetrakis(chloroethyl)phosphorodiamidates has been prepared, and its cytotoxicity has been evaluated against HT-29 cells under aerobic and hypoxic conditions and against murine bone marrow progenitor cells under aerobic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed36a12e7886512c87196696234bd8b
https://doi.org/10.1021/jm00037a011
https://doi.org/10.1021/jm00037a011
Autor:
J.J. Gipp, R.T. Mulcahy
Publikováno v:
Cytogenetic and Genome Research. 88:130-132
Glutamate-L-cysteine ligase (GLCL [EC 6.3.2.2], also referred to as γ-glutamylcysteine synthetase) catalyzes the rate-limiting reaction in the synthesis of the important cellular antioxidant glutathione. GLCL is a heterodimer consisting of a catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30a64802ebf2a46faf07e5d552bbf93
https://doi.org/10.1159/000015505
https://doi.org/10.1159/000015505
Autor:
R.T. Mulcahy, J.J. Gipp
Publikováno v:
Biochemical and biophysical research communications. 209(1)
We have cloned the human γ-glutamylcysteine synthetase heavy subunit gene (GCSh) from a P1 library and isolated a 5.5kb fragment (P1-GCS5′) from the 5′-end of the P1 clone. P1-GCS5′ has been sequenced from −1460 to +547. Multiple transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb86cc6cbf5759f641bf021f437b118
https://pubmed.ncbi.nlm.nih.gov/7726839
https://pubmed.ncbi.nlm.nih.gov/7726839
Autor:
B.J. Morris, R.T. Mulcahy, T. Taguchi, M. Nadal, M.Q. Islam, M.J. Ha, J. Scalzi-Martin, F. Nagai, C. Steinlein, P.A. Ioannou, Y. Endo, J. Weimer, L. Carim, R. Jiménez, J.F. Gui, J.Y. Le Gall, S. Aytay, A. Le Treut, J. Szpirer, R.J. Leach, Y. Zhao, K.P. Fung, S.K.W. Tsui, O. Cremona, D.J. Gilbert, O. Jaillon, C. Ozouf-Costaz, Y. Remache, S. Yoshida, C. Fischer, B. Peral, M. Burgos, N. Inoue, S. Minvielle, N. Berger, K. L. Puschus, A. Goy, A. Kovacic, K. Ilc, A.D. Bi, B. Dupont, R. Gong, L. Yin, T. Faraut, R. Díaz de la Guardia, A. Sánchez, S. Denis, A.C. Clase, P. Amati, L.L. Hansen, A.U. Christoff, J. Yang, P. Bray-Ward, L.D.S. Kok, J. Yoon, G. Calabrese, L. Sumoy, S.S. Siu, Y. Yonenaga-Yassuda, F.J. Lovicu, J. Demongeot, H.S. Kooistra, M. Breen, A.D. Zelenetz, L. Zhou, O. Cohen, S. Shiosaka, M.-A. Mermet, C. Szpirer, J.J. Gipp, M. Harada, Melissa C. Liechty, P. van Vooren, B.L. Barnoski, Y. Wang, W. Feichtinger, S. Cuccato, K. Fukasawa, G. Romeo, R. Giannini, M. Schmid, H. Tamura, H. Satoh, B.K. Hall, K. Gardiner, P De Camilli, J.-F. Laes, M.M. Chen, K. Islam, S. Zhao, B. Levy, N. Arnold, T. Mitsuya, M. Ravoet, W. Kim, T. Werner, A. Hirata, D.C. Ward, Y. Jacques, L van der Weyden, H. Roest Crollius, M. Escarceller, R. Corvi, C. Renier, M. Kiechle, C. Henry, A. Solans, T.M. Dunn, D.J. Adams, J. Justesen, A. Tosolini, H. Zhang, S.V. Reddy, H. Lührs, P. Miccoli, C.A. Moreira-Filho, V. Fagundes, K.E. McVeigh, G. Palka, F. Basolo, B.A. van Oost, C. Dasilva, Y.M. Lee, J.J. Mallee, E. Moon, F. Gilles, G.D. Roodman, L. Bouneau, R. Schaub, B. Toutain, M.L. Little, M. Bullejos, D.W. Cox, S.S. Murthy, L. Guenet, N.A. Jenkins, John Hozier, R. Cinti, S.D.P. Moore, I.S. Lantinga-van Leeuwen, A. Bernot, S. Wu, H.J. Kim, M.M.Y. Waye, L. Stuppia, R. Mural, J.A. Mol, C.R. Müller, F. Magrangeas, T. Menzel, G. Tate, F. Apiou, S. de la Luna, W. Scheppach, G. Torre, M. Gratacòs, G.T. Berry, L. Yu, S.-Y. Zhao, M. Matsui, C. Dubourg, J.R. Testa, C. Haffner, J. Weissenbach, A. Lucente, N. Kardon, X. Quan, R. Jørgensen, U. Weidle, C. M. Carpio, K.M. Fukasawa, V. David, A. Pizzuti, Q. Tu, N.G. Copeland, C. Bonillo, X. Estivill, M. Nimmakayalu, V. Gatta, R. Melcher, C.Y. Lee, J.C. Hozier, M.A. Pujana, J.E. Wiley, I. Fogh, A. Ratti, K. Hirschhorn, Y. Xu
Publikováno v:
Cytogenetic and Genome Research. 88:168-169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57722eaa0a9d3121a81978bd72fb600
https://doi.org/10.1159/000015512
https://doi.org/10.1159/000015512
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 39(1)
SummaryThe quantitative distribution of cell surface alterations of heated P388 ascites tumour cells was determined by scanning electron microscopy. Cells harvested from host animals maintained on a standard rodent chow diet or one high in saturated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44249a636cc3353ae7c8db9178c0cd05
https://pubmed.ncbi.nlm.nih.gov/6971823
https://pubmed.ncbi.nlm.nih.gov/6971823
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 45(5)
SummaryA transplantation system for clonogenic cells in rat thyroid was used, which allows quantitative evaluation of both the acute cytotoxicity and the late neoplastic effects of ionizing radiation at the cellular level in vivo. We have obtained di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4d8de50312f591be620003743f0d42
https://pubmed.ncbi.nlm.nih.gov/6609895
https://pubmed.ncbi.nlm.nih.gov/6609895
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