Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R.S. Pero"'
Autor:
Amir Mohsenin, Michael R. Blackburn, R.S. Pero, Farrah Kheradmand, Eva Morschl, Jose G. Molina, Jonathan B. Volmer, Jeong Soo Hong, James J. Lee
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 39:697-705
Adenosine is a signaling molecule produced during conditions that cause cellular stress or damage. This signaling pathway is implicated in the regulation of pulmonary disorders through the selective engagement of adenosine receptors. The goal of this
Autor:
Elizabeth A. Jacobsen, Cheryl A. Protheroe, Charles C. Irvin, K.R. O'Neill, Nancy A. Lee, R.S. Pero, Sergei I. Ochkur, Travis L. Biechele, Michael R. Blackburn, Thomas V. Colby, James J. Lee, Michael P. McGarry, Dana Colbert, Huahao Shen, Huiying Wang
Publikováno v:
The Journal of Immunology. 178:7879-7889
Mouse models of allergen provocation and/or transgenic gene expression have provided significant insights regarding the cellular, molecular, and immune responses linked to the pathologies occurring as a result of allergic respiratory inflammation. No
Autor:
Lyudmila Sikora, Savita P. Rao, K.R. O'Neill, R.S. Pero, Michael T. Borchers, Hiam Abdala-Valencia, H.H. Shen, Sergei I. Ochkur, Karsten Spicher, Melvin I. Simon, Lutz Birnbaumer, Michael P. McGarry, Nancy A. Lee, James J. Lee, P. Sriramarao, Joan M. Cook-Mills
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4371-4376
The trafficking of leukocytes from the blood to sites of inflammation is the cumulative result of receptor-ligand-mediated signaling events associated with the leukocytes themselves as well as with the underlying vascular endothelium. Our data show t
Autor:
R.S. Pero, Stephanie L. Constant, Dawn Dimina, Sergei I. Ochkur, Cheryl A. Protheroe, Carrie E. Bedient, Thanh H Nguyen, Theresa R. Lombari, Michael P. McGarry, Dana Colbert, K.R. O'Neill, James J. Lee, Nancy A. Lee, Anna G. Taranova, Stephania A. Cormier
Publikováno v:
Journal of Leukocyte Biology. 79:1131-1139
Tumor-associated eosinophilia has been observed in numerous human cancers and several tumor models in animals; however, the details surrounding this eosinophilia remain largely undefined and anecdotal. We used a B16-F10 melanoma cell injection model
Publikováno v:
Infection and immunity. 77(11)
Eosinophils are best known as the predominant cellular infiltrate associated with asthma and parasitic infections. Recently, numerous studies have documented the presence of Toll-like receptors (TLRs) on the surfaces of eosinophils, suggesting that t
Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase
Autor:
Gerd Döring, Alfred D. Doyle, James L. Checkel, Martina Ulrich, Masato Tsutsui, K. Ravi Acharya, Hans-Uwe Simon, Franziska Prömm, Hiroaki Shimokawa, Markus Schirle, Peter Schmid-Grendelmeier, Michael Przybylski, Heinz Schwarz, Michael Schumm, Hirohito Kita, G. Bellon, Alina Petre, Nethaji Thiyagarajan, Nikolay Youhnovski, R.S. Pero, James J. Lee
Publikováno v:
The Journal of biological chemistry. 283(42)
Nitration of tyrosine residues has been observed during various acute and chronic inflammatory diseases. However, the mechanism of tyrosine nitration and the nature of the proteins that become tyrosine nitrated during inflammation remain unclear. Her
Autor:
Nancy A. Lee, Elizabeth A. Jacobsen, James J. Lee, Sergei I. Ochkur, Dana Colbert, R.S. Pero, Cheryl A. Protheroe, Anna G. Taranova
Publikováno v:
The Journal of Experimental Medicine
The current paradigm surrounding allergen-mediated T helper type 2 (Th2) immune responses in the lung suggests an almost hegemonic role for T cells. Our studies propose an alternative hypothesis implicating eosinophils in the regulation of pulmonary
Autor:
Nancy A. Lee, Michael P. McGarry, Charles G. Irvin, R.S. Pero, Sergei I. Ochkur, Lisa Rinaldi, Steven J. Ackerman, Dana Colbert, Thanh H Nguyen, Mi Mi P. Macias, Elizabeth Lenkiewicz, K.R. O'Neill, James J. Lee, Dawn Dimina, Stephania A. Cormier, Cheryl A. Protheroe
Publikováno v:
Science (New York, N.Y.). 305(5691)
Eosinophils are often dominant inflammatory cells present in the lungs of asthma patients. Nonetheless, the role of these leukocytes remains poorly understood. We have created a transgenic line of mice (PHIL) that are specifically devoid of eosinophi
Autor:
Will E. LeSuer, Redwan Moqbel, R.S. Pero, Sergei I. Ochkur, Rachel M. Condjella, Katie R. Zellner, Paige Lacy, Lian Willetts, Elizabeth A. Jacobsen, John D. Kim, Nancy A. Lee, Cheryl A. Protheroe, Hui Lou, James J. Lee
Publikováno v:
Journal of Allergy and Clinical Immunology. 133:AB159
Autor:
Sergei I. Ochkur, Dana Colbert, Nancy A. Lee, Elizabeth A. Jacobsen, Alfred D. Doyle, James J. Lee, Anna G. Taranova, Cheryl A. Protheroe, C.G. Irvin, R.S. Pero, K.R. O'Neill
Publikováno v:
Journal of Allergy and Clinical Immunology. 121:792