Zobrazeno 1 - 10
of 47
pro vyhledávání: '"R.N. Boyes"'
Publikováno v:
Journal of Controlled Release. 10:183-188
The safety and early clinical dental pharmacology of a patch device containing 50 mg of lignocaine was evaluated on a placebo controlled double blind basis in nine volunteers. Application of the patch to the oral mucosa produced soft tissue anaesthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::280d504ee4034987cb24f33ced74a199
https://doi.org/10.1016/0168-3659(89)90061-8
https://doi.org/10.1016/0168-3659(89)90061-8
Publikováno v:
British Journal of Clinical Pharmacology. 7:365-370
1 Prenalterol, (S-(-)-1-(4 hydroxyphenoxy)-3-isopropylaminopropanol-2 hydrochloride) a cardio-selective beta-adrenergic receptor agonist, was infused intravenously into six normal male volunteers to determine the cardiovascular effects of this drug.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ffccf00c9a45ca44b2b2dc5ce4ed0c
https://doi.org/10.1111/j.1365-2125.1979.tb00947.x
https://doi.org/10.1111/j.1365-2125.1979.tb00947.x
Publikováno v:
British Journal of Anaesthesia. 51:481-485
The tolerance and pharmacokinetic properties of mepivacaine and prilocaine were compared following i.v. infusion of 250 mg (0.88 and 0.97 mmol respectively) of each drug in five healthy volunteers. Side-effectrs were minor and occurred in only two su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652954ce8cc59a2722dfdc4d113fd2fb
https://doi.org/10.1093/bja/51.6.481
https://doi.org/10.1093/bja/51.6.481
Publikováno v:
Clinical Pharmacology & Therapeutics. 12:105-116
Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug. Each subject received a constant-rate intravenous infusion lasting for 60 minutes and an exponential intravenous infu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd92c2b5983142a7ac43e442d9c3c0b5
https://doi.org/10.1002/cpt1971121105
https://doi.org/10.1002/cpt1971121105
Autor:
L.M. Clisby, D. Dharmasena, M. Clemenger, D. Howarth, M. Robertson, F.G. Jackson, John Walls, R.N. Boyes, J. McKain, G. Hourahane, C. D. Mistry, Ram Gokal, Stephen L. Smith, E.M. Peers, J. Olubodun, B. J. R. Junor, M. McMillan, Elaine J. Clutterbuck, J. Peters, C. Orton, Timothy H.J. Goodship, Y. M. Beran, Martin Raftery, J. Grieves, A. Gordon Jr, C.B. Brown, J. Michael, D.L. Edwards
Publikováno v:
Kidney International. (2):496-503
A randomized multicenter clinical trial comparing isosmolar Icodextrin with hyperosmolar glucose solutions in CAPD. The osmotic effectiveness of a large molecular weight glucose polymer fraction (Icodextrin) as a novel “colloid” osmotic agent in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd1764c19ec1a3b8c2fc35d21b62c1
Publikováno v:
British Journal of Anaesthesia. 46:668-670
Following release of the tourniquet after intravenous regional anaesthesia (Bier's block) there is a rapid return of sensation in the limb but patchy anaesthesia remains for a varying time. The duration of this residual nerve block was measured in fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11926b72a11f128d6047d0ca9371eae
https://doi.org/10.1093/bja/46.9.668
https://doi.org/10.1093/bja/46.9.668
Publikováno v:
British Journal of Anaesthesia. 45:1010-1012
Fifty mg and 25 mg of bupivacaine and eridocaine were injected intravenously into six volunteers and serial plasma levels were determined. Etidocaine gave significantly lower plasma levels than bupivacaine. Kinetic analyses of the data indicate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedee4abb55e4a952051ea50bab6ec06
https://doi.org/10.1093/bja/45.10.1010
https://doi.org/10.1093/bja/45.10.1010
Publikováno v:
Journal of Investigative Dermatology. 56(2):83-84
The possibility of using a conidial germination test in the evaluation of antifungal chemical was explored using phenol and T. mentagrophytes. The results suggest the feasibility of such a method under carefully controlled conditions. Preventing clum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805f5c967805770bb2b78a23c14ca447
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