Zobrazeno 1 - 10
of 57
pro vyhledávání: '"R.M.G. Nair"'
Publikováno v:
Journal of Urology. 167:1011-1014
The complete amino acid sequence of porcine LH- and FSH-releasing hormone has been provisionally determined by the use on a micro-scale of the combined Edman-dansyl procedure coupled with the selective tritiation method for C-terminal analysis. These
Publikováno v:
Biochemical and Biophysical Research Communications. 43:1376-1381
Summary MSH-release inhibiting hormone (MRIH) activity in bovine hypothalamic extracts, concentrated over 11,000-fold by gel filtration on Sephadex, was further purified by thin-layer chromatography. Two MRIH-active peptides were isolated; one showed
Publikováno v:
Endocrinology. 91:1323-1328
Increased melanocyte-lightening activity was found in the plasma of hypophysectomized rats as assayed by direct application to the pituitaries of frogs which had been previously darkened by removal of the hypothalamus. A decrease in this activity by
Publikováno v:
Journal of Biological Chemistry. 246:7230-7236
A new procedure is described for the isolation on a preparative scale of a hypothalamic decapeptide which stimulates the release of both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. The isolation was achieved ma
Autor:
J. C. Mittler, Abba J. Kastin, Cyril Y. Bowers, Akira Arimura, R.M.G. Nair, Andrew V. Schally, A. J. Segal, Tommie W. Redding, I. Wakabayashi, P. Pizzolato
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 31:291-300
Acetic acid extracts of 339 defatted human hypothalami were subjected to a precipitation procedure and then to separation by several successive steps in order to purify and characterize human releasing hormones.1 Growth hormone-releasing hormone (GH-
Publikováno v:
Neuroendocrinology. 11:92-100
H-Pro-Leu-Gly-NH2, a potentinhibitor of melanocyte stimulating hormone (MSH) release [MSH-release inhibiting factor (MIF)], was labeled with 14C-leucine or 3H-proline and injected i.v. into rats. H-Pro-14C-Leu-Gly-NH2 was found to have a half-life of
Publikováno v:
Neuroendocrinology. 16:36-42
The disappearance of radioactivity after the injection of 14C-labeled-Pro-Leu-Gly-NH2, an MSH release-inhibiting factor (MIF-I), was measured in rats which had been subjected to various procedures. Delayed disappearance of the radioactivity to a smal
Publikováno v:
Journal of Biological Chemistry. 246:6647-6650
The amino acid sequence of a decapeptide with growth hormone-releasing activity, isolated from porcine hypothalami has been determined. The Edman dansyl procedure was used on the intact peptide and on fragments isolated from tryptic and papain digest
Publikováno v:
Thrombosis and Haemostasis.
Elevated plasma von Willebrand factor activity (ristocetin method:VIIIR:WFj and high plasma growth hormone (GH) levels occur in diabetes mellitus. Hypersensitivity of plate lets to aggregating agents is also seen. We have therefore studied the effect
Publikováno v:
Neuroendocrinology. 26(2)
LH-RH or its superactive analogues were infused into pituitary portal vessels of adult male rats for 1 min; pituitaries were then fixed for routine electron microscopy 1 min, 30 min and 3 h after infusion. A maximal increase of granule release at 2 m