Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R.L.G. Sheldrick"'
Publikováno v:
Neuropeptides. 29:281-292
The tachykinin-receptors mediating contraction of human bronchus have been characterized using both tachykinin-receptor selective agonists and blocking drugs under conditions where tachykinin metabolism by endogenous peptidases has been controlled, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e68f8d33cff1d45003b0c4143806a64
https://doi.org/10.1016/0143-4179(95)90037-3
https://doi.org/10.1016/0143-4179(95)90037-3
Publikováno v:
Prostaglandins. 47:151-168
A range of prostanoid agonists were tested for activity on isolated ring preparations of piglet saphenous vein. The selective TxA2-mimetic (TP-receptor agonist), U-46619, contracted the preparation in a concentration-related fashion. These contractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa755165c3c4d0631501c60b87b40a8c
https://doi.org/10.1016/0090-6980(94)90084-1
https://doi.org/10.1016/0090-6980(94)90084-1
Autor:
M.j. Deal, P. Ward, D. Ball, C.C. Jordan, John Martin Pritchard, R.L.G. Sheldrick, R.M. Hagan, G. B. Ewan, I.J.M. Beresford, Andrew B. McElroy, S.J. Ireland, P.W. Smith
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:931-936
A deletion - optimization strategy based on an initial heptapeptide lead structure 1 led to potent and selective neurokinin NK2 antagonists 5 (pKB=9.3) and 9 (pKB=7.9) of substantially reduced molecular size. Tetrapeptide 5 (0.1 μmol/Kg i.v.) potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d3b8a23326bae9166b561132909030
https://doi.org/10.1016/s0960-894x(00)80695-2
https://doi.org/10.1016/s0960-894x(00)80695-2
Autor:
I.J.M. Beresford, E. Kawashima, A. Chollet, P. Ward, J.M. Stables, R.L.G. Sheldrick, P.J. Elliott, J.R.B. Dupere, C.M. Stubbs, R.M. Hagan, A.B. McElroy
Publikováno v:
Regulatory peptides. 46(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f458ecb60f874ad83d50239e2033fc2
https://pubmed.ncbi.nlm.nih.gov/8210508
https://pubmed.ncbi.nlm.nih.gov/8210508
Publikováno v:
Neuropeptides. 22:50-51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb1fa997ee3469aad255132b25f5405
https://doi.org/10.1016/0143-4179(92)90466-a
https://doi.org/10.1016/0143-4179(92)90466-a
Publikováno v:
Neuropeptides. 24:190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24afe1a47a6f23a7bff58a5bcdbaf77
https://doi.org/10.1016/0143-4179(93)90127-v
https://doi.org/10.1016/0143-4179(93)90127-v
Publikováno v:
Neuropeptides. 24:189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ea46ae711f86a82d0d672b2a4f26b
https://doi.org/10.1016/0143-4179(93)90124-s
https://doi.org/10.1016/0143-4179(93)90124-s
Publikováno v:
Neuropeptides. 24:190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47edf51f2bfa812adab497d325288ae0
https://doi.org/10.1016/0143-4179(93)90128-w
https://doi.org/10.1016/0143-4179(93)90128-w
Publikováno v:
Neuropeptides. 24:191
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db75504f220ca5e618bfed3849a80f8
https://doi.org/10.1016/0143-4179(93)90130-3
https://doi.org/10.1016/0143-4179(93)90130-3
Publikováno v:
Neuropeptides. 24:189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5959016487004f283bb80b7e3d57596
https://doi.org/10.1016/0143-4179(93)90125-t
https://doi.org/10.1016/0143-4179(93)90125-t