Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury

Autor: P. Medeiros, I.R. dos Santos, A.C. Medeiros, J.A. da Silva, S.H. Ferreira, R.L. de Freitas, N.C. Coimbra

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 53, Iss 5 (2020)

The neurochemical mechanisms underlying neuropathic pain (NP) are related to peripheral and central sensitization caused by the release of inflammatory mediators in the peripheral damaged tissue and ectopic discharges from the injured nerve, leading

Externí odkaz: https://doaj.org/article/ab7d93ad877044c79c4ca650ec9dc9c4

Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT1A and CB1 receptors

Autor: Ana Carolina Medeiros, R.B. Malvestio, Sabatino Maione, R.L. de Freitas, Sylmara Esther Negrini-Ferrari, Mariana Oliveira-Silva, L. Luongo, Norberto Cysne Coimbra, Patrícia Medeiros, Cláudia Maria Padovan

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The prelimbic division (PrL) of the medial prefrontal cortex (mPFC) is a cerebral division that is putatively implicated in the chronic pain and depression. We investigated the activity of PrL cortex neurons in Wistar rats that underwent chronic cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bf8d42825240e4c6d3c03e2b1f59f8
https://doi.org/10.1016/j.brainresbull.2021.06.017

Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury

Autor: I.R. dos Santos, Patrícia Medeiros, Norberto Cysne Coimbra, R.L. de Freitas, J.A. da Silva, S H Ferreira, Ana Carolina Medeiros

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Medical and Biological Research v.53 n.5 2020
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 53, Iss 5 (2020)

The neurochemical mechanisms underlying neuropathic pain (NP) are related to peripheral and central sensitization caused by the release of inflammatory mediators in the peripheral damaged tissue and ectopic discharges from the injured nerve, leading

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3804e6e3bf402eea059af4755aa53809

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