Zobrazeno 1 - 10
of 212
pro vyhledávání: '"R.K. Boutwell"'
Autor:
R.K. Boutwell
Publikováno v:
Nutrition and Biotechnology in Heart Disease and Cancer ISBN: 9781461358046
Gene therapy for cancer is on the horizon and gene prophylaxis is likely under specific circumstances. However, prevention, or at least a lowered risk of developing cancer is possible now. The knowledge to accomplish prevention is based primarily on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::003a643efcf0a40e5bcd0915b6c80031
https://doi.org/10.1007/978-1-4615-1957-7_11
https://doi.org/10.1007/978-1-4615-1957-7_11
Autor:
Ajit K. Verma, R.K. Boutwell
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 677:184-189
Arginase, which catalyzes the cleavage of l -arginine to urea and ornithine, was detected in both soluble and particulate fractions of mouse epidermis. In a typical experiment, about 75 and 25% of the total arginase activity was associated with the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15961c9ce619b4d85479a93d815caf57
https://doi.org/10.1016/0304-4165(81)90083-0
https://doi.org/10.1016/0304-4165(81)90083-0
Autor:
Ajit K. Verma, R.K. Boutwell
Publikováno v:
Biochemical and Biophysical Research Communications. 96:854-862
A simple method to culture explants of adult mouse skin in a modified Eagle's HeLa cell medium was developed in order to further study the biochemical responses to the tumor promoting phorbol esters. The skin explants remained viable for at least 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944322661711f835314e9a3aa59d92ec
https://doi.org/10.1016/0006-291x(80)91434-5
https://doi.org/10.1016/0006-291x(80)91434-5
Publikováno v:
Journal of Investigative Dermatology. 69(6):547-550
Exposure of mouse skin to microwave radiation for 10 sec allows the epidermis to be separated from the dermis by gentle scraping of the skin with a scapel. At the end of the irrradiation period the subcutaneous temperature was 55 degrees C. Histologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f46cb70d7d0014e9992fa8dd882af7
Publikováno v:
Cancer Letters. 29:79-84
The tumor promoter 12- O -tetradecanoylphorbol-13-acetate (TPA) and the non-promoter mezerein both induce ornithine decarboxylase activity in mouse epidermis by a route which can be blocked by indomethacin. In two-stage tumor promotion experiments in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140748909f588192d6fc0f5fcf618e1b
https://doi.org/10.1016/0304-3835(85)90126-0
https://doi.org/10.1016/0304-3835(85)90126-0
Autor:
R.K. Boutwell, Gollamudi S. Kishore
Publikováno v:
Biochemical and Biophysical Research Communications. 94:1381-1386
Evidence is presented for the ability of mouse epidermis to oxidize retinal by the action of a cytosolic enzyme with a pH optimum of about 8.5. The enzyme activity was slightly enhanced by the addition of either NAD or FAD. The reaction exhibited Mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da01f8a4e48410ea4c9a9efe059f815
https://doi.org/10.1016/0006-291x(80)90572-0
https://doi.org/10.1016/0006-291x(80)90572-0
Publikováno v:
International Journal of Biochemistry. 15:885-889
1. 1. Ornithine decarboxylase was purified at least 1500-fold from mouse epidermis pretreated with five consecutive doses of 12-O-tetradecanoylphorbol-13-acetate and 3-isobutyl-l-methylxanthine at 3- to 4-day intervals. 2. 2. Following DEAE-cellulose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6af84ecb8b90369ff3f2e9c3232235b
https://doi.org/10.1016/0020-711x(83)90163-5
https://doi.org/10.1016/0020-711x(83)90163-5
Publikováno v:
Biochemical and Biophysical Research Communications. 120:593-601
Cellular retinol-binding protein (cRBP) and cellular retinoic acid-binding protein (cRABP) were purified from calf liver and uterus, respectively. Soluble Ca+2- phosphatidylserine-dependent protein kinase-C (PK-C) derived from mouse brain was capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6192ceac9919fc5765ce90399d76696b
https://doi.org/10.1016/0006-291x(84)91296-8
https://doi.org/10.1016/0006-291x(84)91296-8
Autor:
Curtis L. Ashendel, R.K. Boutwell
Publikováno v:
Biochemical and Biophysical Research Communications. 90:623-627
After topical application of tumor-promoting phorbol esters, immunoreactive prostaglandins E and F in mouse epidermis were increased several-fold over basal levels. The increases were doubled by 3 hours and lasted until 5 days after phorbol ester tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738c5851cc68e3b9d8dc85a6af312e8b
https://doi.org/10.1016/0006-291x(79)91280-4
https://doi.org/10.1016/0006-291x(79)91280-4
Publikováno v:
Biochemical and Biophysical Research Communications. 138:330-334
Cellular retinol-binding protein, cellular retinoic acid-binding protein, and fetal cellular retinol-binding protein were purified to homogeneity and each polypeptide had a molecular weight of 16,000. Their apoproteins were not phosphorylated under t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199ef9392045b2d5c899ef336ae9f6c2
https://doi.org/10.1016/0006-291x(86)90284-6
https://doi.org/10.1016/0006-291x(86)90284-6