Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R.J.H. Stenekes"'
Publikováno v:
International Journal of Pharmaceutics. 214:17-20
A novel delivery concept based on the encapsulation of liposomes in biodegradable dextran microspheres was developed. The microspheres were prepared using a two-phase system, consisting of water/poly(ethylene glycol), and water/methacrylated dextran.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ad63b0ec574840535072193dbb31e3
https://doi.org/10.1016/s0378-5173(00)00625-6
https://doi.org/10.1016/s0378-5173(00)00625-6
Autor:
Joseph Demeester, Wim E. Hennink, Stefaan C. De Smedt, R.J.H. Stenekes, Zhibing Zhang, Guangzhi Sun
Publikováno v:
Biomacromolecules. 1:696-703
The average pore size of hydrated dextran microspheres is derived from rheological and protein release data. The microspheres were prepared by cross-linking an aqueous solution of methacrylated dextran emulsified in a continuous poly(ethylene glycol)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bed928d56378f7ff222a4260ed5978
https://doi.org/10.1021/bm005574a
https://doi.org/10.1021/bm005574a
Autor:
R.J.H. Stenekes, Wim E. Hennink
Publikováno v:
Polymer. 41:5563-5569
Cross-linking of dextran can be established by derivatization of the polysaccharide with methacryloyl groups followed by polymerization of an aqueous solution of this methacrylated dextran with an initiator system consisting of potassium peroxydisulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667700607991f8d51610e0fdd7565508
https://doi.org/10.1016/s0032-3861(99)00814-9
https://doi.org/10.1016/s0032-3861(99)00814-9
Publikováno v:
Pharmaceutical Research. 15:557-561
Purpose. The purpose of this study was to investigate the effect of the formulation parameters on the characteristics of dextran-based microspheres, prepared in an all-aqueous system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f653a487acb8cf165402aaf9c67396f
https://doi.org/10.1023/a:1011925709873
https://doi.org/10.1023/a:1011925709873
Autor:
J.A. Cadée, S. J. de Jong, R.J.H. Stenekes, Herre Talsma, Wilhelmus Everhardus Hennink, O. Franssen, W. N. E. Van Dijk-Wolthuis
Publikováno v:
Biomedical Polymers and Polymer Therapeutics ISBN: 9780306464720
A biodegradable and biocompatible dextran hydrogel system has been developed of which the degradation time can be tailored between 2 days and 3 months. This chapter shows that hydrogels based on crosslinked dextrans have unique properties as protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c72c29c90180a291acf30ba874d7d66
https://doi.org/10.1007/0-306-46842-5_1
https://doi.org/10.1007/0-306-46842-5_1
Publikováno v:
Biomaterials. 22(13)
In this paper, a novel method is presented for the preparation of dextran hydrogels and microspheres, based on crystallization. Although dextrans are known to be well soluble in water, precipitation was observed in concentrated aqueous solutions of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35d031e0e5ea17ccaaa565074452e20
https://pubmed.ncbi.nlm.nih.gov/11396895
https://pubmed.ncbi.nlm.nih.gov/11396895
Autor:
Wim E. Hennink, R.J.H. Stenekes
Publikováno v:
International journal of pharmaceutics. 189(2)
In this paper a method is presented to determine the equilibrium water content of microspheres with a hydrogel character based on cross-linked dextran. The water content was established by determination of the increase in blue dextran concentration a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09675cbe3a6dd50cc791a46bbc96b060
https://pubmed.ncbi.nlm.nih.gov/10536241
https://pubmed.ncbi.nlm.nih.gov/10536241
Publikováno v:
International journal of pharmaceutics. 183(1)
A novel procedure to prepare dextran microspheres, without the use of organic solvents was developed. The method is based on phase separation which occurs in aqueous solutions of PEG and methacrylated dextran (dexMA). After stirring this two phase sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfcd6e9a10546729d70ce9c8f37deaf
https://pubmed.ncbi.nlm.nih.gov/10361149
https://pubmed.ncbi.nlm.nih.gov/10361149
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.