Zobrazeno 1 - 10
of 103
pro vyhledávání: '"R.J. Pinney"'
Autor:
J.E. Ambler, R.J. Pinney
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 351:181-186
The post-UV phenotypes conferred by wild-type plasmids R391 and pYD1, which increase UV-induced mutagenesis but sensitise Escherichia coli AB1157 umuC+ uvrB+ to UV, were compared, alone and in combination with that of plasmid pGW16, which sensitises
Publikováno v:
European Journal of Pharmaceutical Sciences. 2:221-228
R plasmids, which increased resistance of Staphylococcus aureus and Escherichia coli to a variety of pharmaceutical preservatives, were shown, using the protocol of the Preservative Efficacy Test of the British Pharmacopoeia (1988), to influence the
Publikováno v:
Chemotherapy. 40:232-238
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 249:177-187
Plasmid pKM101, which carries muc genes that are analogous in function to chromosomal umu genes, protected Escherichia coli strains AB1157 uvrB+ umuC+, JC3890 uvrB umuC+, TK702 uvrB+ umuC and TK501 uvrB umuC against ultraviolet irradiation (UV). Plas
Autor:
L. Radnedge, R.J. Pinney
Publikováno v:
FEMS Microbiology Letters. 79:121-126
A new form of restriction alleviation is demonstrated for phage induced by ultraviolet light from dcm strains of Escherichia coli K-12. Eco RII restriction of the induced phage is alleviated, which is the first report of Type II restriction alleviati
Autor:
R.J. Pinney, P.V. Attfield
Publikováno v:
Mutation Research Letters. 139:101-105
Escherichia coli strain TK701 umu+ was more resistant than strain TK702 umu when tested against bleomycin (BLM), cis-platinum(II) diamminodichloride (PDD), ultraviolet light and methyl methanesulphonate (MMS), which produce single-strand DNA damage.
Autor:
P.V. Attfield, R.J. Pinney
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 107:1-12
Plasmid R46 was tested for its ability to increase survival and mutagenesis of Escherichia coli strain AB1157 following exposure to agents that produce a variety of structural defects in DNA. The plasmid enhanced the mutagenic activities of adriamyci
Autor:
J.T. Smith, R.J. Pinney
Publikováno v:
Chemotherapy. 20:296-302
Strains of Escherichia coli were constructed that harboured 1, 2 or 3 independent R factors, and their antibiotic resistance levels determined by a spot-testing technique on solid m
Autor:
P.V. Attfield, R.J. Pinney
Publikováno v:
FEMS Microbiology Letters. 28:287-291
Drugs that damage DNA by different mechanisms eliminate an F- lac + plasmid and multicopy plasmid R6K from Escherichia coli K-12 wild type ( polA + rec + ). However, low-copy plasmid R1 is refractory to elimination under identical conditions. R6K is
Publikováno v:
Mutagenesis. 4:90-94
4-Acetoxy-3-acetoxymethyl acetophenone (AAMAP) is mutagenic in Ames Salmonella typhimurium tester strains TA100 and TA98, which carry plasmid pKM101, but not in the isogenic plasmid-less strains TA1535 and TA1538. Similarly, no AAMAP-induced reversio