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pro vyhledávání: '"R.J. Marley"'
Akademický článek
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Publikováno v:
Alcohol. 24:69-78
A restriction fragment length polymorphism (RFLP) associated with a major nicotinic receptor subunit (i.e., alpha4) has been identified in two mouse lines that were selectively bred for differences in sensitivity to ethanol. These mice, referred to a
Akademický článek
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Publikováno v:
Neuropharmacology. 30:245-251
The repeated, intraperitoneal administration of the benzodiazepine receptor inverse agonist, FG 7142 (β-carboline-3-carboxylic acid methylamide), leads to pharmacological kindling and an associated decrease in GABA-stimulataed influx of 36 Cl − in
Publikováno v:
Brain Research. 542:1-7
Repeated administration of doses of cocaine below the threshold for seizure induction results in the development of an increased susceptibility to cocaine-induced seizures (cocaine-kindling). Genetic differences in susceptibility to cocaine-kindled s
Publikováno v:
Brain research. 600(2)
Initial studies of the effect of chronic carbamazepine (CBZ) against cocaine-induced seizures indicated that there were genetic differences in both the time course for the development of the anticonvulsant effects of CBZ against cocaine-induced seizu
Autor:
Nancy Ellen C. de Fiebre, R.J. Marley, Jeanne M. Wehner, Lucinda L. Miner, Christopher M. de Fiebre, Allan C. Collins
Publikováno v:
Alcoholism, clinical and experimental research. 16(3)
A classical (Mendelian) genetic analysis of responses to eight sedative-hypnotic compounds (ethanol, urethane, trifluoroethanol, chloral hydrate, barbital, paraldehyde, methyprylon, pentobarbital) was conducted in crosses derived from mouse lines tha
Autor:
R.J. Marley, Steven R. Goldberg
Publikováno v:
Brain research. 579(1)
The effects of chronic carbamazepine (CBZ) on the development and expression of cocaine-kindled seizures and seizures produced by an acute injection of cocaine were evaluated in BALB/cByJ, C57B1/6J and SJL/J mice. The repeated administration of a sub
Publikováno v:
Life sciences. 50(4)
Rats were made sensitive to the effects of the opioid antagonist naltrexone by treating them once weekly with cumulative doses of the drug (1, 3, 10, 30 and 100 mg/kg). Sensitization was monitored by measuring salivation following naltrexone administ
A pharmacogenetic evaluation of the role of local anesthetic actions in the cocaine kindling process
Publikováno v:
Brain research. 562(2)
Repeated administration of subconvulsant doses of lidocaine or cocaine results in the development of an increased susceptobility to seizures induced by the two drugs (pharmacological kindling). It has been hypothesized that the local anesthetic prope