Expression profiling of ABC transporters in peripheral blood lymphocytes and monocyte-derived macrophages of rheumatoid arthritis patients

Autor: Rieneke van de Ven, J.W. van der Heijden, R.J. Scheper, B A C Dijkmans, G.J. Peters, Gerrit Jansen, George L. Scheffer, Ruud Oerlemans, Marjolein Blits, W.F. Lems, Yehuda G. Assaraf

Publikováno v: Oerlemans, R, Blits, M, Dijkmans, BAC, van der Heijden, JW, Lems, WF, Scheffer, GL, van de Ven, R, Peters, GJ, Assaraf, Y G, Scheper, RJ & Jansen, G 2020, ' Expression profiling of ABC transporters in peripheral blood lymphocytes and monocyte-derived macrophages of rheumatoid arthritis patients ', Journal of Molecular and Clinical Medicine, vol. 3, no. 2, 2020.02.007, pp. 47-60 . https://doi.org/10.31083/j.jmcm.2020.02.007
Journal of Molecular and Clinical Medicine, 3(2):2020.02.007, 47-60

In autoimmune diseases like rheumatoid arthritis (RA), multidrug resistance (MDR) transporters of the ATP-binding cassette (ABC) transporter superfamily harbor dual functions by extruding pro-inflammatory mediators and exporting disease modifying ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0065cb71d6b80f0bb82bb431f8d08e92
https://research.vumc.nl/en/publications/9da1945b-c0d2-4f5c-a658-dc382a6e644c

A study looking at the differences between hypertrophic scars and keloid scars

Autor: Susan Gibbs, J.M. Belien, Grace C. Limandjaja, R.J. Scheper, Frank B. Niessen

Publikováno v: British Journal of Dermatology. 182

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0eefe59b2e3fea2b263430f7f995872e
https://doi.org/10.1111/bjd.18907

Potential method to determine irritant potency in vitro – Comparison of two reconstructed epidermal culture models with different barrier competency

Autor: Susan Gibbs, Sander W. Spiekstra, R.J. Scheper, G.G. dos Santos

Publikováno v: Toxicology in Vitro, 23(2), 349-355. Elsevier Limited
Spiekstra, S W, dos Santos, G G, Scheper, R J & Gibbs, S 2009, ' Potential method to determine irritant potency in vitro-Comparison of two reconstructed epidermal culture models with different barrier competency ', Toxicology in Vitro, vol. 23, no. 2, pp. 349-355 . https://doi.org/10.1016/j.tiv.2008.12.010

Testing chemicals for their ability to cause skin irritation is required for all ingredients of products that come into contact with the skin. Here, we describe a potential method for determining the irritant potency of a chemical in vitro and apply

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a9493581b49927dd175ef9dbd7ff31
https://doi.org/10.1016/j.tiv.2008.12.010

Continuing the quest for autoimmunity due to oral metal exposure

Autor: Joris Muris, Cees J. Kleverlaan, R.J. Scheper, B.M.E. von Blomberg, Dessy Rachmawati, Albert J. Feilzer, I.M.W. van Hoogstraten, Thomas Rustemeyer

Publikováno v: Autoimmunity, 48(7), 494-501. Informa Healthcare
Rachmawati, D, Muris, J, Scheper, R J, Rustemeyer, T, Kleverlaan, C J, Feilzer, A J, von Blomberg, B M E & van Hoogstraten, I M W 2015, ' Continuing the quest for autoimmunity due to oral metal exposure ', Autoimmunity, vol. 48, no. 7, pp. 494-501 . https://doi.org/10.3109/08916934.2015.1033688

Aim: The role of metal exposure in the development of autoimmune disease (AID) is still controversial. Here, we studied the relationship between oral metal exposure, metal allergy and autoimmunity. Methods: A mixed population (n = 78) of non-allergic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb110013d0b65274ca9d40c2b64ede1
https://research.vumc.nl/en/publications/86338a1c-0bb5-4000-bc96-9371f2a05efd

CXCL8 secretion by dendritic cells predicts contact allergens from irritants

Autor: R.J. Scheper, M.J. Toebak, Susan Gibbs, Derk P. Bruynzeel, Thomas Rustemeyer, B.M.E. von Blomberg, Paula R. Pohlmann, Shakun C. Sampat-Sardjoepersad

Publikováno v: Toebak, M J, Pohlmann, P R, Sampat-Sardjoepersad, S C, Von Blomberg, B M E, Bruynzeel, D P, Scheper, R J, Rustemeyer, T & Gibbs, S 2006, ' CXCL8 secretion by dendritic cells predicts contact allergens from irritants ', Toxicology in Vitro, vol. 20, no. 1, pp. 117-124 . https://doi.org/10.1016/j.tiv.2005.06.039
Toxicology in Vitro, 20(1), 117-124. Elsevier Limited

Monocyte-derived dendritic cell functions have been explored for identification of contact allergens in vitro. Current methods, including measurement of changes in cell surface marker expression (e.g. CD83, CD86) do not provide a sensitive method for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b285a42a1c7f855e78dfb8e0327945
https://doi.org/10.1016/j.tiv.2005.06.039