Zobrazeno 1 - 10
of 81
pro vyhledávání: '"R.G. Sutcliffe"'
Publikováno v:
Biochemical and biophysical research communications. 208(3)
Integral membrane proteins anchor to the cell surface and span the lipid bilayer by an α-helix of 17-30 amino acids, the transmembrane segment. However, little is known about the association of this α-helix and the lipid bilayer. In the present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1ec208dba934e56ec8258d56b1be4e
https://pubmed.ncbi.nlm.nih.gov/7702612
https://pubmed.ncbi.nlm.nih.gov/7702612
Autor:
A.W. Bowman, A.B. Maclean, R.G. Sutcliffe, Hamish W. Sutherland, B.M. Kukulska-Langlands, S. Gibb, C.H.W. Horne, V. Jandial
Publikováno v:
Placenta. 3:71-79
Pregnancy-associated plasma protein-A was assayed in the blood of 347 women during pregnancy, using a new primary standard of PAPP-A as reference. The protein was assayed by antibody-antigen crossed electrophoresis with the lower limit of confident a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ae01cddf58b2b9ab951b9e198a62fa
https://doi.org/10.1016/s0143-4004(82)80020-9
https://doi.org/10.1016/s0143-4004(82)80020-9
Autor:
N. Abu-Hasan, R.G. Sutcliffe
Publikováno v:
Placenta. 5:71-82
Summary Microvillous M-PAP and A-PAP were purified to homogeneity from butanol extracts of syncytiotrophoblastic microvillous membranes using DEAE Sepharose CL-6B chromatography. The two isoenzymes had indistinguishable pH optima and K m values. Unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596944a2c7e1308c77811e243fd72434
https://doi.org/10.1016/s0143-4004(84)80050-8
https://doi.org/10.1016/s0143-4004(84)80050-8
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 13:333-342
This study was designed as an assessment of the clinical value of total estriol, placental lactogen (hPL), pregnancy specific glycoprotein (SP1), pregnancy-associated plasma protein-A (PAPP-A) and placental protein 5 (PP5), measured in a single sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad55ad70c49ad502acfc8dab9b70aa9
https://doi.org/10.1016/0028-2243(82)90068-5
https://doi.org/10.1016/0028-2243(82)90068-5
Autor:
R.G. Sutcliffe, N. Abu-Hasan
Publikováno v:
Placenta. 6:391-404
Human placental microvillous alkaline phosphatase (M-PLAP) was extracted from microvilli either by butanol extraction or subtilisin proteolysis. The data indicate that subtilisin cleavage of PLAP removes a membrane-binding domain of approximately 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18329c74333e9c613f17ca1c56dd19cd
https://doi.org/10.1016/s0143-4004(85)80016-3
https://doi.org/10.1016/s0143-4004(85)80016-3
Autor:
Christine H. Gore, R.G. Sutcliffe
Publikováno v:
Placenta. 5:293-313
Summary Pregnancy-associated plasma protein A (PAPP-A) has been obtained in an enriched state under mild conditions of purification involving cibacron blue dye-ligand chromatography, negative antibody-affinity chromatography and gel filtration. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2254102a66000630006838e4eb50b0
https://doi.org/10.1016/s0143-4004(84)80011-9
https://doi.org/10.1016/s0143-4004(84)80011-9
Autor:
R.G. Sutcliffe, David J. H. Brock
Publikováno v:
Clinica Chimica Acta. 31:363-365
The activities of five enzymes, isocitrate dehydrogenase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, phosphohexose isomerase and lactate dehydrogenase have been measured in amniotic fluid cells at different stages of pregnan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dd3c32c2ffd1855ec7bbe8399ba8a5
https://doi.org/10.1016/0009-8981(71)90404-9
https://doi.org/10.1016/0009-8981(71)90404-9
Autor:
R.G. Sutcliffe, David J. H. Brock
Publikováno v:
The Lancet. 300:197-199
α-fetoprotein (A.F.P.) has been measured in the amniotic fluids of thirty-one pregnancies leading to anencephaly (or anencephaly and spina bifida), three leading to spina bifida, and three leading to hydrocephaly (or hydrocephaly and spina bifida).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2735fb3745cf5937eba0a0ae7c9e57
https://doi.org/10.1016/s0140-6736(72)91634-0
https://doi.org/10.1016/s0140-6736(72)91634-0
Publikováno v:
Placenta. 8(3)
A protein factor has been found in serum which converts the M form of placental alkaline phosphatase (PLAP) to the A and B forms. The identity of the conversion products has been confirmed by analysis of their dimers and polypeptides. Proteolysis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982d1e614ded0d510cf6a0534bd5174e
https://pubmed.ncbi.nlm.nih.gov/3658925
https://pubmed.ncbi.nlm.nih.gov/3658925
Publikováno v:
Placenta. 5(2)
Summary A high molecular weight form of human placental alkaline phosphatase has been detected in extracts of placenta at term by electrophoresis in starch gels containing 0.5 per cent Triton X-100. The enzyme has a mobility intermediate between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ed4d065cefaa7be7ad97ef5f71ed08
https://pubmed.ncbi.nlm.nih.gov/6483813
https://pubmed.ncbi.nlm.nih.gov/6483813