Zobrazeno 1 - 10
of 207
pro vyhledávání: '"R.G. Gosden"'
Autor:
John Huntriss, Susan E. Lanzendorf, R.G. Gosden, Sarah E. Harris, Brian G. Oliver, Anthony J. Rutherford, Helen M. Picton, M. Hinkins, J.C. Beazley
Publikováno v:
Molecular Reproduction and Development. 67:323-336
Recent evidence indicates that mammalian gametogenesis and preimplantation development may be adversely affected by both assisted reproductive and stem cell technologies. Thus, a better understanding of the developmental regulation of the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb455bafc9573bc57e50bd11f36a1b39
https://doi.org/10.1002/mrd.20030
https://doi.org/10.1002/mrd.20030
Publikováno v:
Fertility and Sterility. 75:269-274
Objective: To develop a new protocol for conserving fertile potential in men undergoing sterilizing chemotherapy by low temperature banking of germ cells which can be returned to the patient's testes after thawing. Design: Isolation of human and muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a849910e193202ac9ba4da60405c4641
https://doi.org/10.1016/s0015-0282(00)01721-0
https://doi.org/10.1016/s0015-0282(00)01721-0
Publikováno v:
Molecular Human Reproduction. 5:1107-1114
Transferrin is produced primarily by the liver and is best known as a carrier of iron in the circulation. Transferrin is also produced extra-hepatically where it may serve to suppress the generation of reactive oxygen species and act as a growth fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c1a15ea2e0581dd939717db676ace6
https://doi.org/10.1093/molehr/5.12.1107
https://doi.org/10.1093/molehr/5.12.1107
Publikováno v:
Human Reproduction. 13:1133-1138
In contrast to the many detailed studies of Graafian follicles, the biology of small follicles in the human ovary is poorly understood and the trigger for follicular growth initiation remains unknown. No practical model exists to study preantral foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea1556384378515a71afe576c3c9bb8
https://doi.org/10.1093/humrep/13.5.1133
https://doi.org/10.1093/humrep/13.5.1133
Publikováno v:
Human Reproduction. 13:376-380
The recent improvements in the treatment of cancer by chemo- and radiotherapy have led to a significant increase in the survival rates of patients with malignant disease, but at the expense of distressing side effects. One major problem, especially f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c086998bdfc00e7e5df5a8acba5630c8
https://doi.org/10.1093/humrep/13.2.376
https://doi.org/10.1093/humrep/13.2.376
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:3748-3751
FSH stimulates antral follicles to grow, but its role in earlier stages, if any, is obscure. Our aim was to determine the follicle stage at which the FSH receptor (FSHr) gene is first expressed. We used a PCR-based strategy to analyze single follicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a765d923c45d6342bf091d41942dfef3
https://doi.org/10.1210/jcem.82.11.4346
https://doi.org/10.1210/jcem.82.11.4346
Autor:
Malcolm J. Faddy, R.G. Gosden
Publikováno v:
Human Reproduction. 10:770-775
A mathematical model has been developed to describe the rates of growth and death of follicles in human ovaries between 19 and 50 years of age. It was based on the numbers of follicles at three successive stages of development, which were obtained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69da36f01c56572c71c75357e07efe87
https://doi.org/10.1093/oxfordjournals.humrep.a136036
https://doi.org/10.1093/oxfordjournals.humrep.a136036
Autor:
Malcolm J. Faddy, R.G. Gosden
Publikováno v:
Human Reproduction. 11:1484-1486
The store of primordial follicles in the ovary is fixed before birth and dwindles with age until it is unable to provide enough Graafian stages to sustain menstrual cyclicity. According to a simple bi-exponential model of ageing, the rate of follicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79330ee068e4b711fd031e6f4e46aa52
https://doi.org/10.1093/oxfordjournals.humrep.a019422
https://doi.org/10.1093/oxfordjournals.humrep.a019422
Publikováno v:
Nature. 403(6769)
In females of many species, over half of the germ-cell (oocyte) population dies by apoptosis before birth1. For example, germ-cell numbers peak at 5–7×106 at week 20 of gestation in humans, but drop to less than 1×106 in the early neonatal period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79690ad410b4f6e7ec41acdfee98a8f
https://pubmed.ncbi.nlm.nih.gov/10676949
https://pubmed.ncbi.nlm.nih.gov/10676949