Zobrazeno 1 - 10
of 171
pro vyhledávání: '"R.F. Kimball"'
Autor:
R.F. Kimball, Bernice F. Hirsch
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 30:9-20
A number of chemicals have been tested for their ability to produce novobiocin-resistant mutants in Haemophilus influenzae. Of these, hydrazine (HZ) proved unique because it induced a fairly high incidence of mutation without killing significant numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed211b248087d182ff7d8b94e1cdb2e4
https://doi.org/10.1016/0027-5107(75)90248-1
https://doi.org/10.1016/0027-5107(75)90248-1
Autor:
M.E. Boling, R.F. Kimball
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 37:1-9
Three temperature-sensitive mutants of the Haemophilus influenzae phage HP1c1 were tested for reversion to wild type (ts leads to ts+). Treatment with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) produced revertants at levels up to 0.1% of the total p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e40bf546f9362fb82a7cc864aa2a0b9
https://doi.org/10.1016/0027-5107(76)90050-6
https://doi.org/10.1016/0027-5107(76)90050-6
Autor:
R.F. Kimball
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 72:347-359
Evidence in previous publications has suggested that treatment with monofunctional alkylating agents such as N-methyl-N′-nitro-nitroguanidine (MNNG) results in gaps being left in the DNA synthesized shortly after the treatment. This paper presents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8fd7edc46393c4b3d910667070c86c
https://doi.org/10.1016/0027-5107(80)90110-4
https://doi.org/10.1016/0027-5107(80)90110-4
Autor:
R.F. Kimball
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 39:111-126
Hydrazine has a number of uses in industry as an antioxidant for boiler and cooling-tower water and as a source material for synthesizing a wide range of pharmaceuticals and plant growth inhibitors. Hydrazine can react with the pyrimidines in DNA to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4d56fba7e0baca7b1296633d686d78
https://doi.org/10.1016/0165-1110(77)90018-5
https://doi.org/10.1016/0165-1110(77)90018-5
Autor:
Stella W. Perdue, R.F. Kimball
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 80:249-258
Evidence is presented to show that presumptive frameshift mutations induced in Haemophilus influenzae by ICR-191 are fixed very rapidly, essentially at the time of treatment. DNA synthesis during treatment is essential for fixation, but DNA synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59f9bcd0df993b3676e9517918808da
https://doi.org/10.1016/0027-5107(81)90097-x
https://doi.org/10.1016/0027-5107(81)90097-x
Publikováno v:
Experimental Cell Research. 84:111-120
Microspectrophotometric and autoradiographic procedures were used to determine cell protein content and cell cycle parameters of Chinese hamster V79 cells growing as monolayer cultures with daily renewal of medium. The frequency of G 1 cells decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7362a6397852d796e0a5692ae4bf26
https://doi.org/10.1016/0014-4827(74)90386-3
https://doi.org/10.1016/0014-4827(74)90386-3
Autor:
Jane K. Setlow, R.F. Kimball
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 22:1-14
A transformation assay has been used to follow the fixation of mutations to novobiocin resistance induced by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) in Haemophilus influenzae. Very few mutations are produced by recently treated DNA, but many ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba11a2c60f2da504044ee560d8c17bd6
https://doi.org/10.1016/0027-5107(74)90002-5
https://doi.org/10.1016/0027-5107(74)90002-5
Publikováno v:
Experimental Cell Research. 95:416-424
N6,O2′-dibutyryl adenosine 3′,5′-cyclic-phosphate (db-cAMP) has been shown to convert Chinese hamster cells of ovarian origin (CHO-K1) from compact, randomly oriented cells growing in multilayers to elongated fibroblast-like cells which grow in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446e6764df65aed6c598f26afb294e34
https://doi.org/10.1016/0014-4827(75)90567-4
https://doi.org/10.1016/0014-4827(75)90567-4
Autor:
R.F. Kimball
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 8:79-89
Studies were made of mutations induced by ultraviolet radiation in Paramecium aurelia . The mutation yield is a maximum when the paramecia are exposed to UV just before or perhaps during the S period and is less the longer the time between irradiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13972e5d939cfd3ac5905e074d00cc82
https://doi.org/10.1016/0027-5107(69)90143-2
https://doi.org/10.1016/0027-5107(69)90143-2
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 13:289-295
The effects of posttreatment incubation on single-strand breaks in the DNA of Haemophilus influenzae treated in vivo with methyl methanesulfonate (MMS) and N -methyl- N ′-nitro- N -nitrosoguanidine (MNNG) were studied. Immediately after treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4943d78058ebe29aa422a34a000e2186
https://doi.org/10.1016/0027-5107(71)90039-x
https://doi.org/10.1016/0027-5107(71)90039-x