Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R.Craig Schnell"'
Autor:
Jeffrey R. Means, R.Craig Schnell
Publikováno v:
Toxicology Letters. 3:177-184
After cadmium treatment (2.0 mg Cd/kg, i.p.) a marked inhibition is observed in microsomal drug metabolizing enzyme activity which is correlated with a reduction in the hemoprotein, cytochrome P-450, content. Incorporation of the heme precursor, 3H-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98153c26457905d8b0a9e93177dd5641
https://doi.org/10.1016/0378-4274(79)90019-5
https://doi.org/10.1016/0378-4274(79)90019-5
Publikováno v:
Biochemical Pharmacology. 24:877-881
Three days after a single cadmium dose (2 mg/kg), the duration of response to subsequently administered hexobarbital or zoxazolamine was potentiated. Duration of sleep was prolonged (225 per cent) in cadmium-treated rats, but the awakening plasma hex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d17ae1f5ba4fa34bb5de1fecd644d05
https://doi.org/10.1016/0006-2952(75)90158-6
https://doi.org/10.1016/0006-2952(75)90158-6
Autor:
R.Craig Schnell, Robert O. Warwick
Publikováno v:
European Journal of Pharmacology. 38:329-335
Experiments were conducted to determine if the acute hypothermia elicited by morphine in the rat resulted from morphine-induced inhibition of serotonin reuptake into hypothalamic nerve-endings. The acute hypothermia elicited by morphine (30 mg/kg, s.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7c078ef929d837637e8cbbe14f36bf
https://doi.org/10.1016/0014-2999(76)90336-8
https://doi.org/10.1016/0014-2999(76)90336-8
Publikováno v:
Toxicology and Applied Pharmacology. 39:89-96
Three days after ip administration of a single cadmium dose (0.84 mg of Cd/kg), duration of hexobarbital hypnosis was significantly potentiated in male but not in female rats. Cadmium in larger doses of 2, 4, and 6 mg/kg, ip, did not alter duration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5acc8fcad6242d3cf91879fd6b3fec1
https://doi.org/10.1016/0041-008x(77)90180-6
https://doi.org/10.1016/0041-008x(77)90180-6
Publikováno v:
Toxicology Letters. 17:193-200
The effect of sodium selenite administered acutely or repeatedly on the biochemical components of the hepatic microsomal monooxygenase enzyme system was examined in male rats. 72 h following acute administration of selenium (2.4 mg Se/kg, i.p.), ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbd96153669ed48982fd5534f1fd38c
https://doi.org/10.1016/0378-4274(83)90057-7
https://doi.org/10.1016/0378-4274(83)90057-7
Autor:
R.Craig Schnell, Johnnie L. Early
Publikováno v:
Toxicology and Applied Pharmacology. 58:57-66
Experiments were undertaken to examine the effect of selenium, an essential trace element, on cadmium-induced inhibition of drug metabolism in male, Sprague-Dawley derived rats. Prior administration of sodium selenite (1.6 mg Se/kg, ip) blocked the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae8c5656774312c88fcaff64ecd6e87
https://doi.org/10.1016/0041-008x(81)90115-0
https://doi.org/10.1016/0041-008x(81)90115-0
Autor:
Stanley A. Roberts, R.Craig Schnell
Publikováno v:
Toxicology and applied pharmacology. 64(1)
Experiments were undertaken to determine if a correlation existed between the time-dependent synthesis of hepatic metallothionein and the development of tolerance to the inhibition of hepatic drug oxidation elicited by cadmium in the male rat. Maxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd94151814e5f3acb1f6c523648eec0
https://pubmed.ncbi.nlm.nih.gov/7112583
https://pubmed.ncbi.nlm.nih.gov/7112583
Autor:
R.Craig Schnell, Deborah H. Pence
Publikováno v:
Toxicology letters. 5(5)
3 days following an intraperitoneal injection of cadmium [Cd] (2.0 mg Cd/kg) an inhibition in hepatic microsomal drug metabolism for ethylmorphine and aniline was observed in male rats. Such treatment in female rats only inhibited metabolism of anili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f877de2a30371ca32ad86cb2395b36f
https://pubmed.ncbi.nlm.nih.gov/7385254
https://pubmed.ncbi.nlm.nih.gov/7385254
Autor:
R.Craig Schnell, Johnny L. Early
Publikováno v:
Toxicology letters. 11(3-4)
Pretreatment of male rats with diethylmaleate (DEM) (3.1 mmol/kg) markedly decreased the levels of reduced glutathione in both liver (81%) and kidney (44%). Acute lethality produced by sodium selenite (0.4 to 2.4 mg Se/kg) was greatly enhanced in DEM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a636545f8313550c264ba69cd0f8a9
https://pubmed.ncbi.nlm.nih.gov/7101319
https://pubmed.ncbi.nlm.nih.gov/7101319
Publikováno v:
Toxicology. 6(3)
3 days after pretreatment of rats of both sexes with cadmium (2 mg/kg, i.p.) the duration of hypnosis induced by hexobarbital (75 mg/kg, i.p.) was potentiated in males but not females. Likewise, similar treatment with cadmium leads to significant inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c9f0d68c4960e2be5830a4ecfb35bd
https://pubmed.ncbi.nlm.nih.gov/996874
https://pubmed.ncbi.nlm.nih.gov/996874