Zobrazeno 1 - 10
of 224
pro vyhledávání: '"R.C.F. Leonard"'
Autor:
B.J. Milner, David E. Parkin, Neva E. Haites, Henry C Kitchener, A.M. Lessells, I.D. Miller, D.M. Eccles, L Allan, Marion K Campbell, R.C.F. Leonard
Publikováno v:
International Journal of Gynecological Cancer. 6:483-490
Mutation of the p53 tumor suppressor gene is the most commonly observed genetic abnormality in human tumors and associations between p53 aberration and patient survival have been shown for several tumor types. Previous studies have found that approxi
Publikováno v:
The Breast. 5:259-264
Autor:
A. Cremaschi, A. Van Dalen, Petra Stieber, Rafael Molina, S. Saracchini, R.C.F. Leonard, Catharine M. Sturgeon, R. Einarsson, K.J. Heering, P. Geroni, Massimo Gion, Vivian Barak, Tamar Peretz, M. Namer
Publikováno v:
The Breast. 5:82-88
One hundred and twenty-nine patients with dissiminated breast cancer were selected to study the clinical applicability of changes in CA 15-3, tissue polypeptide specific antigen (TPS) and carcinoembryonic antigen (CEA) during therapy and how these co
Publikováno v:
International Journal of Gynecologic Cancer. 2:134-140
The relatively high incidence of amplification and overexpression of the neu (c-erb B2/HER-2) oncogene in breast cancer, and its association with poor prognosis, particularly in node negative patients, may allow identification of patients who require
Autor:
R.C.F. Leonard, R.L. Hayward, R.J. Prescott, J.-X. Wang, N.C. Allan, A. Barrett, S.N. Das, A.A. Dawson, A. Heppleston, A.M. Lessells, N.P. Lucie, H.H. Lucraft, M.J. Mackie, K.S. MacLaren, A.C. Parker, S.J. Proctor, T.K. Sarkar, T. Sheehan, M. Soukop, W.P. Steward, J.M. White
Publikováno v:
Annals of Oncology. 2:655-662
Summary A prognostic model was developed by examination of the prospectively recorded presentation characteristics of patients presenting with low grade non-Hodgkin's lymphomas (LGL). A geographically distinct group (Edinburgh and Borders) was exclud
Publikováno v:
Breast (Edinburgh, Scotland). 18(4)
Anthracyclines are valuable cytotoxic agents in cancer treatment. However, their usefulness is limited by cumulative dose-dependent cardiotoxicity that may manifest as life-threatening congestive heart failure. To avoid cardiotoxicity, the use of dox
Publikováno v:
Pediatric bloodcancer. 44(3)
Background Despite recommendations that adolescents should have in-patient management amongst their peers, there is little literature to support this. The study aim was to evaluate and contrast patient satisfaction for teenage cancer patients treated
Publikováno v:
European Journal of Cancer. 37:27
Publikováno v:
European Journal of Cancer. 37:11
Autor:
R.C.F. Leonard, S. Povey, G. McIntyre, R. Salazar, C. Twelves, A. Hutcheon, D. Bissett, T. Bates, A. Chaturvedl, S. Chan, J. Carmichael
Publikováno v:
European Journal of Cancer. 37:28
Following the encouraging results achieved with the oral fluoropyrimidine capecitabine in clinical trials, a named patient programme was initiated in the UK, through which patients with advanced breast cancer were prescribed capecitabine monotherapy.