Zobrazeno 1 - 10
of 81
pro vyhledávání: '"R.C. van der Schors"'
Autor:
Jacqueline Wubben, August B. Smit, R.E. van Kesteren, Sam O. Hofman, Iryna Paliukhovich, R.C. van der Schors, P. van Nierop, S.K. Franke, Ingrid H.C.H.M. Philippens
Publikováno v:
Neuroscience, 312, 247-259. Elsevier Limited
Franke, S K, van Kesteren, R E, Wubben, J A, Hofman, S, Paliukhovich, I, van der Schors, R C, van Nierop, P, Smit, A B & Philippens, I H C H M 2016, ' Progression and recovery of Parkinsonism in a chronic progressive MPTP-induction model in the marmoset without persistent molecular and cellular damage ', Neuroscience, vol. 312, pp. 247-259 . https://doi.org/10.1016/j.neuroscience.2015.09.065
Franke, S K, van Kesteren, R E, Wubben, J A, Hofman, S, Paliukhovich, I, van der Schors, R C, van Nierop, P, Smit, A B & Philippens, I H C H M 2016, ' Progression and recovery of Parkinsonism in a chronic progressive MPTP-induction model in the marmoset without persistent molecular and cellular damage ', Neuroscience, vol. 312, pp. 247-259 . https://doi.org/10.1016/j.neuroscience.2015.09.065
Chronic exposure to low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in marmoset monkeys was used to model the prodromal stage of Parkinson's disease (PD), and to investigate mechanisms underlying disease progression and recovery. Marmose
Autor:
Ning Chen, Danielle Posthuma, L.N. Cornelisse, Gregoire Maroteaux, Ka Wan Li, S. van der Sluis, Matthijs J. H. M. van der Loos, P. van Nierop, Asiya Giniatullina, Bastijn Koopmans, R.C. van der Schors, Ruud F. Toonen, A.P.H. de Jong, Alexander J. Groffen, Remco V. Klaassen, Matthijs Verhage, W.D. Altrock, August B. Smit, Oliver Stiedl, Patrick F. Sullivan, Cornelia J. Geerts
Publikováno v:
Giniatullina, A, Maroteaux, G P, Geerts, C J, Koopmans, B, Loos, M, Klaassen, R V, Chen, N, van der Schors, R C, van Nierop, P, Li, K W, de Jong, A P H, Altrock, W D, Cornelisse, L N, Toonen, R F G, van der Sluis, S, Sullivan, P F, Stiedl, O, Posthuma, D, Smit, A B, Groffen, A J A & Verhage, M 2015, ' Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences ', Neuroscience, vol. 300, pp. 518-538 . https://doi.org/10.1016/j.neuroscience.2015.05.047
Neuroscience, 300, 518-538. Elsevier Limited
Neuroscience, 300, 518-538. Elsevier Limited
Genome-wide association studies have suggested a role for a genetic variation in the presynaptic gene PCLO in major depressive disorder (MDD). As with many complex traits, the PCLO variant has a small contribution to the overall heritability and the
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Autor:
Ka Wan Li, Andrea Schmitt, Jale Sahin, Michael R. Kreutz, Karl-Heinz Smalla, Eckart D. Gundelfinger, Marina Mikhaylova, H.-G. Bernstein, B. Bogerts, August B. Smit, R.C. van der Schors
Publikováno v:
Smalla, K H, Mikhaylova, M, Sahin, J, Bernstein, H G, Bogerts, B, Schmitt, A, van der Schors, R C, Smit, A B, Li, K W, Gundelfinger, E D & Kreutz, M R 2008, ' A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia ', Molecular Psychiatry, vol. 13, pp. 878-896 . https://doi.org/10.1038/mp.2008.60
Molecular Psychiatry, 13, 878-896. Nature Publishing Group
Molecular Psychiatry, 13, 878-896. Nature Publishing Group
Many studies in recent years suggest that schizophrenia is a synaptic disease that crucially involves a hypofunction of N-methyl-D-aspartate receptor-mediated signaling. However, at present it is unclear how these pathological processes are reflected
Autor:
A.E. Gioio, Maria Eyman, Ka Wan Li, R.C. van der Schors, J. Van Minnen, Antonio Giuditta, Barry B. Kaplan, Wijnand P. M. Geraerts, Z. Scotto Lavina, Connie R. Jimenez
Publikováno v:
Journal of Neurochemistry. 81:735-744
A proteomics approach was used to identify the translation products of a unique synaptic model system, squid optic lobe synaptosomes. Unlike its vertebrate counterparts, this preparation is largely free of perikaryal cell fragments and consists predo
Autor:
R.C. van der Schors, Paul J. Hensbergen, Maria Ponec, Cornelis P. Tensen, I.L.A. Boxman, Derk P. Bruynzeel
Publikováno v:
British journal of dermatology, 146(5), 777-785
British journal of dermatology 146 (2002) 5
British journal of dermatology 146 (2002) 5
SummaryBackground There is an increasing need for screening of mild irritants in vitro to reduce animal testing. Objectives Proteomics were used to search for new markers of which the expression changes after mild irritation. Methods Sodium lauryl su
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 36:728-733
Insulin of the Black Sea rockfish Scorpaena porcus was isolated, purified, and the primary sequence has been determined. The hormone amino acid sequence has been established: the A chain—GIVEQCCNRPCNIFDLQNYCN, and the B chain—AAGPQHLCGSHLVDALYLVC
Autor:
Kingsley J. A. Cox, Wijnand P. M. Geraerts, H. van Heerikhuizen, R.C. van der Schors, Rob Leurs, Cornelis P. Tensen, Julian F. Burke, E. Vreugdenhil
Publikováno v:
European Journal of Neuroscience. 10:3409-3416
Neuropeptide Y is an abundant and physiologically important peptide in vertebrates having effects on food intake, sexual behaviour, blood pressure and circadian rhythms. Neuropeptide Y homologues have been found in invertebrates, where they are very
Autor:
R.E. van Kesteren, R.C. van der Schors, Ka Wan Li, Wijnand P. M. Geraerts, F. A. Van Golen, R. P. J. de Lange
Publikováno v:
Neuroscience. 69:1275-1287
We examined functional aspects of co-localization of neuropeptides involved in the regulation of male copulation behaviour in the simultaneous hermaphrodite snail Lymnaea stagnalis . The copulation behaviour is controlled by several types of peptider
Autor:
J. Van Der Greef, F Smith, R.C. van der Schors, Connie R. Jimenez, Ka Wan Li, R. M. Hoek, S Chen, D C Parish, P R Benjamin, P. A. Van Veelen
Publikováno v:
Journal of Biological Chemistry. 269:30288-30292
A novel strategy combining peptide fingerprinting of single neurons by matrix-assisted laser desorption ionization mass spectrometry, molecular cloning, peptide chemistry, and electrospray ionization mass spectrometry was used to study the intricate