Zobrazeno 1 - 10
of 58
pro vyhledávání: '"R.B. Nicklas"'
Publikováno v:
Journal of Cell Science. 111:3189-3196
Many cells have a checkpoint that detects a single misattached chromosome and delays anaphase, allowing time for error correction. Detection probably depends on tension-sensitive kinetochore protein phosphorylation. Somehow, mechanical tension, or so
Autor:
X. Li, R.B. Nicklas
Publikováno v:
Journal of cell science. 110
Improper chromosome attachment to the spindle can lead to daughter cells with missing or extra chromosomes. Such mishaps are avoided in many cells by a checkpoint that detects even a single improperly attached chromosome. What is detected? A misattac
Autor:
P. Arana, R.B. Nicklas
Publikováno v:
Journal of cell science. 102
We used an evolutionary test to ask whether the congression of chromosomes to the spindle equator is important in itself or just a mitotic happenstance. If congression matters, then it might evolve if absent initially. Previous workers established th
Publikováno v:
Trends in Genetics. 9:264
Errors in chromosome orientation in mitosis and meiosis are inevitable, but normally they are quickly corrected. We find that such errors usually are not corrected in cells treated with protein kinase inhibitors. Highly inaccurate chromosome distribu
Publikováno v:
Journal of Cell Science. 94:415-423
We have discovered an easy way to cut through the mitotic spindle at any desired place. Spindles of demembranated cricket or grasshopper spermatocytes were severed with a microneedle between the chromosomes and one pole, and the cut-off polar piece w
Publikováno v:
Journal of Cell Science. 35:87-104
A new method is offered for combined living cell and electron-microscopic studies of spermatocytes (or other cells) which normally do not adhere to glass. The key step is microinjection of glutaraldehyde near the target cell whenever desired during o
Publikováno v:
Journal of Cell Science. 6:323-350
Low-temperature (10 °C) treatments alternated with periods at room temperature (25 °C) were found to induce grossly abnormal kinetochore orientation behaviour during metaphase I in spermatocytes of the grasshopper Melanoplus differentialis. These o
Publikováno v:
Proceedings, annual meeting, Electron Microscopy Society of America. 46:32-33
The mitotic spindle is composed chiefly of microtubules (MTs) and functions to equally distribute the replicated chromosomes to daughter cells. Spindles are generated from an interaction between the spindle poles and kinetochores. The former are resp
Kniha
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Akademický článek
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