Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse

Autor: Werner Müller, R.A. Morawetz, R L Coffman, T M Doherty, Fred D. Finkelman, Lucia Gabriele, Ralf Kühn, Luiz Vicente Rizzo, Herbert C. Morse, Nancy Noben-Trauth, Klaus Rajewsky

Publikováno v: The Journal of Experimental Medicine
Scopus-Elsevier

Immunoglobulin (Ig) class switching in B cells is regulated by stimuli transduced by cytokines and cell-cell contact. Among these stimuli, interleukin (IL)-4 has been considered an absolute prerequisite for class switching to IgE in the mouse. Here w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469a18de1a24766cc85dba1950e9266d
https://doi.org/10.1084/jem.184.5.1651

Relationship of cytokines and cytokine signaling to immunodeficiency disorders in the mouse

Autor: Lucia Gabriele, R.A. Morawetz, Keiko Ozato, N.A. Giese, Herbert C. Morse, P. Rothman, I. Horak

Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 31, Issue: 1, Pages: 61-67, Published: JAN 1998
Brazilian Journal of Medical and Biological Research, Vol 31, Iss 1, Pp 61-67 (1998)
Scopus-Elsevier
Brazilian Journal of Medical and Biological Research v.31 n.1 1998
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC

The contributions of cytokines to the development and progression of disease in a mouse model of retrovirus-induced immunodeficiency (MAIDS) are controversial. Some studies have indicated an etiologic role for type 2 cytokines, while others have emph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a16fb561392372dbf195b38caeb9012
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100008&lng=en&tlng=en

Cytokine-dependent modulation of oral tolerance in a murine model of autoimmune uveitis

Autor: Herbert C. Morse, Nancy E. Miller-Rivero, Luiz Vicente Rizzo, Chi-Chao Chan, Robert B. Nussenblatt, Leslie R. Stiff, R.A. Morawetz, Barbara Wiggert, Rachel R. Caspi

Publikováno v: Annals of the New York Academy of Sciences. 778

In summary, our data suggest that oral tolerance in the mouse EAU model may occur by anergy/deletion or by suppression, depending on the feeding regimen. Tolerance involving putative regulatory cells appears to require the ability to produce both IL-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703408eb698206e41b6f949a90ce7d70
https://pubmed.ncbi.nlm.nih.gov/8610985

Cells and cytokines in the pathogenesis of MAIDS, a retrovirus-induced immunodeficiency syndrome of mice

Autor: Janet W. Hartley, Herbert C. Morse, Wan Kee Kim, Tang Y, N.A. Giese, Ricardo T. Gazzinelli, R.A. Morawetz, Sisir K. Chattopadhyay

Publikováno v: Scopus-Elsevier

MAIDS is a retrovirus-induced immunodeficiency syndrome of mice that develops as a consequence of multiple interactions between T and B cells. The disease develops in response to infection with a defective virus encoding a Pr60gag protein that is myr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debc89ed2fb57103dbc5e62778cb5e56
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029148232&partnerID=MN8TOARS

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