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pro vyhledávání: '"R.A. Cone"'
Akademický článek
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Publikováno v:
Journal of Controlled Release. 50:93-102
Several recent studies suggest that direct application of antigen to the vaginal surface may enhance local IgA secretion, but the most effective methods for stimulating immunity at the vaginal surface have not been identified. We used antigen-loaded,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2507120a347092b9224540cccc77e8
https://doi.org/10.1016/s0168-3659(97)00114-4
https://doi.org/10.1016/s0168-3659(97)00114-4
Publikováno v:
Biophysical Journal. 66:508-515
The mucosal immune system actively transports large quantities of antibodies into all mucus secretions, and these secreted antibodies help prevent infectious entry of many pathogens. Mucus is generally thought to protect epithelial cells by forming a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de1013b053c9d27d97bfaa21be1618e
https://doi.org/10.1016/s0006-3495(94)80802-1
https://doi.org/10.1016/s0006-3495(94)80802-1
Publikováno v:
Biology of Reproduction. 47:133-140
Controlled delivery of monoclonal antibodies to the mucus secretions of the vagina might provide women with passive immunoprotection against both sexually transmitted diseases and unwanted pregnancy. We have developed intravaginal devices composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::363b23ffaa50ba5b87cb9d6a7608b9a6
https://doi.org/10.1095/biolreprod47.1.133
https://doi.org/10.1095/biolreprod47.1.133
Publikováno v:
Biology of Reproduction. 43:485-491
The relative tensile strengths of the sperm of seven mammalian species and sea urchins have been measured by determining the minimum shear necessary to kill them (assayed by lack of motility) when they are suspended in a viscous fluid. In general, lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11955123bc9e692c97f2e818bac546d7
https://doi.org/10.1095/biolreprod43.3.485
https://doi.org/10.1095/biolreprod43.3.485
Akademický článek
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Publikováno v:
Journal of reproductive immunology. 40(1)
An IgG2a monoclonal antibody (Mab) directed against glycoprotein D of herpes simplex virus 2 (HSV-2) was compared with an IgA heavy chain Mab switch variant to investigate the effect of isotype for topical immunoprotection of the murine vagina. The I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3568235ddc714f2212e76be54e543720
https://pubmed.ncbi.nlm.nih.gov/9862259
https://pubmed.ncbi.nlm.nih.gov/9862259
Autor:
K. J. Whaley, Pp Sanna, Thomas R. Moench, Dennis R. Burton, R A Williamson, R.A. Cone, Raiza Bastidas, Larry Zeitlin, A De Logu
Publikováno v:
Virology. 225(1)
A recombinant human anti-herpes simplex virus monoclonal IgG1antibody and the corresponding Fab and F(ab′)2fragments were tested for efficacy in preventing vaginal transmission of HSV-2 infection in a well-established mouse model for genital herpes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c2faf18a1b682ff8b1763d2d4efb76
https://pubmed.ncbi.nlm.nih.gov/8918548
https://pubmed.ncbi.nlm.nih.gov/8918548
Publikováno v:
Biology of reproduction. 54(1)
Antibodies delivered directly to the vagina can provide passive immunoprotection against pregnancy and sexually transmitted disease. The duration of protection is limited by the residence time of the antibodies in the vagina; to our knowledge such re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e940c84403e5d63ef6e28032706e8a2a
https://pubmed.ncbi.nlm.nih.gov/8838025
https://pubmed.ncbi.nlm.nih.gov/8838025
Akademický článek
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