Zobrazeno 1 - 10
of 85
pro vyhledávání: '"R. van der Neut"'
Autor:
J J Keller, Elles M. J. Boon, Francis M. Giardiello, S. T. Pals, G. J. A. Offerhaus, T.A.M. Wormhoudt, R van der Neut
Publikováno v:
Boon, E M J, Keller, J J, Wormhoudt, T A M, Giardiello, F M, Offerhaus, G J A, Van Der Neut, R & Pals, S T 2004, ' Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines ', British Journal of Cancer, vol. 90, no. 1, pp. 224-229 . https://doi.org/10.1038/sj.bjc.6601505
British journal of cancer, 90(1), 224-229. Nature Publishing Group
British Journal of Cancer, 90(1), 224-229. Nature Publishing Group
British Journal of Cancer
British journal of cancer, 90(1), 224-229. Nature Publishing Group
British Journal of Cancer, 90(1), 224-229. Nature Publishing Group
British Journal of Cancer
Nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive potential against colorectal carcinomas (CRCs). Inhibition of cyclooxygenase (COX)-2 underlies part of this effect, although COX-2-independent mechanisms may also exist. Nonsteroidal
Autor:
Jero Calafat, A.S. Cachaco, Arnoud Sonnenberg, J. Bulthuis, R. van der Neut, S. Thorsteinsdottir, D. Prins, Hans Janssen, M. A. Van Der Valk
Publikováno v:
Journal of Cell Science. 112:3911-3922
Integrin beta4 null mice exhibit extensive epidermal detachment, reminiscent of the human skin blistering disease junctional epidermolysis bullosa associated with pyloric atresia. Hemidesmosomes, the stable adhesion structures of squamous epithelia,
Publikováno v:
Nature Genetics. 13:366-369
Integrins are heterodimeric transmembrane glycoproteins which are engaged in a variety of cellular functions, such as adhesion, migration and differentiation1. The integrin alpha 6 beta 4 is expressed on squamous epithelia, on subsets of endothelial
Publikováno v:
Journal of Biological Chemistry. 268:436-441
Proteolytic removal and genetic deletion of the amino-terminal domain of G protein alpha subunit have shown that this region is necessary for interaction with beta gamma subunits. In the alpha subunits which undergo myristoylation, myristoylation of
Publikováno v:
Peptides. 13:1109-1115
Using ELISAs for B-50/GAP43 and neurofilament (NF), we tested ACTH(1-24), alpha-MSH, ACTH(4-10), and an ACTH(4-9) analogue (ORG2766) for their ability to induce sprouting and neuritogenesis from spinal and sensory neurons. Dissociated fetal rat spina
Publikováno v:
70th EAGE Conference and Exhibition incorporating SPE EUROPEC 2008.
In the Virtual Source (VS) method we cross-correlate recordings at two receiver locations to create data as if one of these receivers is a Virtual Source and the other is a receiver. We study the amplitude radiation pattern of Virtual Sources. This p
Publikováno v:
70th EAGE Conference and Exhibition incorporating SPE EUROPEC 2008.
SUMMARY Seismic Green's function retrieval or seismic interferometry (SI) refers to the principle of generating new seismic responses by crosscorrelating seismic observations at different receiver locations. We consider retrieving a reflection respon
Publikováno v:
British Journal of Cancer, 92(6), 1078-1083. Nature Publishing Group
Boon, E M J, Kovarikova, M, Derksen, P W B & Van Der Neut, R 2005, ' MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling ', British Journal of Cancer, vol. 92, no. 6, pp. 1078-1083 . https://doi.org/10.1038/sj.bjc.6602405
British Journal of Cancer
Boon, E M J, Kovarikova, M, Derksen, P W B & Van Der Neut, R 2005, ' MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling ', British Journal of Cancer, vol. 92, no. 6, pp. 1078-1083 . https://doi.org/10.1038/sj.bjc.6602405
British Journal of Cancer
It has been shown that in hereditary and most sporadic colon tumours, components of the Wnt pathway are mutated. The Wnt target MET has been implicated in the development of colon cancer. Here, we show that overexpression of wild-type or a constituti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4f1d8bd7affb25202a7bb03b681acb
https://research.vumc.nl/en/publications/723d69b7-bb66-437d-aacd-4c9cb1f84aef
https://research.vumc.nl/en/publications/723d69b7-bb66-437d-aacd-4c9cb1f84aef
Autor:
S. Hartmann, Wolfgang Schaper, Jan J. Piek, T.A.M. Wormhoudt, Marco M. Jost, S. de Graaf, N. van Royen, C. Bode, Jing Hua, Ivo Buschmann, F. Hedwig, R. van der Neut, S. T. Pals, Michiel Voskuil, J.-P. Andert, Imo E. Hoefer
Publikováno v:
Circulation, 109(13), 1647-1652. Lippincott Williams and Wilkins
Background—Arteriogenesis refers to the development of collateral conductance arteries and is orchestrated by circulating monocytes, which invade growing collateral arteries and act as suppliers of cytokines and growth factors. CD44 glycoproteins a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6899d434659ff9809562993dddb6b9
https://pure.amc.nl/en/publications/cd44-regulates-arteriogenesis-in-mice-and-is-differentially-expressed-in-patients-with-poor-and-good-collateralization(5acb37de-af3f-498d-b470-863833a30062).html
https://pure.amc.nl/en/publications/cd44-regulates-arteriogenesis-in-mice-and-is-differentially-expressed-in-patients-with-poor-and-good-collateralization(5acb37de-af3f-498d-b470-863833a30062).html
Autor:
Jordan A. Kreidberg, Richard O. Hynes, Elisabeth N. Georges-Labouesse, C.M. DiPersio, A. Sonnenberg, R. van der Neut
Publikováno v:
Journal of cell science. 113
Continuous regeneration and homeostasis of the stratified epidermis requires coordinated regulation of cell proliferation, cell differentiation, and cell survival. Integrin-mediated cell adhesion to the extracellular matrix has important roles in reg