Multi-scale in silico and ex silico mechanics of 3D printed cochlear implants for local drug delivery

Autor: A. Isaakidou, M. Ganjian, R. van Hoften, M. C. Saldivar, M. A. Leeflang, A. Groetsch, M. Wątroba, J. Schwiedrzik, M. J. Mirzaali, I. Apachitei, L. E. Fratila-Apachitei, A. A. Zadpoor

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)

The currently available treatments for inner ear disorders often involve systemic drug administration, leading to suboptimal drug concentrations and side effects. Cochlear implants offer a potential solution by providing localized and sustained drug

Externí odkaz: https://doaj.org/article/ca457da64f0b4457954a8304befa356c

Cerebral tissue oxygen saturation and extraction in preterm infants before and after blood transfusion

Autor: Paul Keating, Elise A. Verhagen, Jacorina C R van Hoften, Hendrik J. ter Horst, Arend F. Bos

Publikováno v: ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 95(5), F352-F358. BMJ PUBLISHING GROUP

Objective Preterm infants often need red blood cell (RBC) transfusions. The aim of this study was to determine whether haemoglobin levels before transfusion were associated with regional cerebral tissue oxygen saturation (r c SO 2 ) and fractional ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27efc1e0889bc9a9ade68559e099994
https://pubmed.ncbi.nlm.nih.gov/20466739

Multi-scale in silico and ex silico mechanics of 3D printed cochlear implants for local drug delivery.

Autor: Isaakidou A; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Ganjian M; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., van Hoften R; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Saldivar MC; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Leeflang MA; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Groetsch A; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory of Mechanics of Materials and Nanostructures, Thun, Switzerland.; Department of Materials Science and Engineering, Henry Samueli School of Engineering, University of California, Irvine, Irvine, CA, United States., Wątroba M; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory of Mechanics of Materials and Nanostructures, Thun, Switzerland., Schwiedrzik J; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory of Mechanics of Materials and Nanostructures, Thun, Switzerland., Mirzaali MJ; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Apachitei I; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Fratila-Apachitei LE; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands., Zadpoor AA; Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Delft, Netherlands.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2024 Jan 31; Vol. 11, pp. 1289299. Date of Electronic Publication: 2024 Jan 31 (Print Publication: 2023).