Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival

Autor: S L Kunkel, T J Standiford, E Broug-Holub, G B Toews, R M Strieter, J F van Iwaarden, R. rd. Paine

Publikováno v: Immunology, 65, 1139-1146. Wiley-Blackwell
Broug-Holub, E, Toews, G B, Iwaarden, I J, Strieter, R M, Kunkel, S L, 3rd. Paine, R & Standiford, T J 1997, ' Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival ', Immunology, vol. 65, pp. 1139-1146 .

To study the in vivo role of alveolar macrophages (AM) in gram-negative bacterial pneumonia in mice, AM were eliminated by the intratracheal (i.t.) administration of dichloromethylene diphosphonate encapsulated liposomes. Subsequently, the AM-deplete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d8085faea9ce51a830158dfb7362cf
https://doi.org/10.1128/iai.65.4.1139-1146.1997