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Akademický článek
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Autor:
Michael Schulzer, R. de la Fuente-Fernandez, Thomas J. Ruth, A. J. Stoessl, André R. Troiano, Edwin Mak, Vesna Sossi
Publikováno v:
Neurology. 72:1211-1216
Objective: Dyskinesias are common in Parkinson disease (PD). Prior investigations suggest that dopamine (DA) terminals compensate for abnormal DA transmission. We verified whether similar adaptations could be related to the development of treatment-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ab49086353a44e8054c3ea4ec81e8b
https://doi.org/10.1212/01.wnl.0000338631.73211.56
https://doi.org/10.1212/01.wnl.0000338631.73211.56
Autor:
Thomas J. Ruth, M. Zamburlini, M.-L. Camborde, A. J. Stoessl, R. de la Fuente-Fernandez, Vesna Sossi
Publikováno v:
IEEE Transactions on Nuclear Science. 51:205-211
Background/Objectives: In this paper, we address the issue of how the preprocessing steps of a typical neuroreceptor PET study may influence the outcome of a statistical parametric mapping (SPM) analysis examining intercondition differences. Two prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a69507d7fe52b24a108dd2f71b067e2a
https://doi.org/10.1109/tns.2003.823030
https://doi.org/10.1109/tns.2003.823030
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 23:301-309
Parkinson disease is characterized by the loss of dopaminergic neurons, thus decreasing the system's ability to produce and store dopamine (DA). Such ability is often investigated using 18F-fluorodopa (FD) positron emission tomography. A commonly use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82ef97697b2189d073ede51e5b2db41
https://doi.org/10.1097/01.wcb.0000050041.22945.3e
https://doi.org/10.1097/01.wcb.0000050041.22945.3e
Publikováno v:
Parkinsonism & Related Disorders. 9:201-204
We examined the clinical features of familial (n = 26) and sporadic (n = 52) Parkinson's disease (PD) in patients presenting over the age of 40 years. Familial PD cases were tested for alpha-synuclein or parkin mutations as appropriate. No mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28a2b9480a1a2e254c543f8b5507fe3
https://doi.org/10.1016/s1353-8020(02)00048-2
https://doi.org/10.1016/s1353-8020(02)00048-2
Autor:
Edwin Mak, R. de la Fuente-Fernandez, Barry J. Snow, Thomas J. Ruth, T. G. Nygaard, A. J. Stoessl, D. B. Calne, A. B. Naini, Michael Schulzer, Asha Kishore
Publikováno v:
Neurology. 50:1028-1032
We tested the hypothesis that asymptomatic carriers of dopa-responsive dystonia (DRD) have increased dopamine D2 receptors in the striatum that protect them from the clinical manifestations of dopaminergic deficiency. We examined striatal D2-receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2c8329986315711c1e1ce806036673
https://doi.org/10.1212/wnl.50.4.1028
https://doi.org/10.1212/wnl.50.4.1028
Autor:
I M Turnbull, S Yardley, Asha Kishore, R. de la Fuente-Fernandez, Edwin Mak, Michael Schulzer, D. B. Calne, Barry J. Snow
Publikováno v:
Brain. 120:729-737
We tested the efficacy, stability and predictors of outcome of unilateral pallidotomy used to treat patients with Parkinson's disease inadequately controlled with pharmacotherapy (IP). The surgical procedure was as simple as possible; we used CT rath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd134ff3cebf365c82fce32d90130d4
https://doi.org/10.1093/brain/120.5.729
https://doi.org/10.1093/brain/120.5.729
Autor:
R. de la Fuente-Fernandez, G. Biju
Publikováno v:
Parkinsonismrelated disorders. 15
Recent PET studies in Parkinson's disease (PD) have shown that the progression of neurodegeneration follows an exponential decay pattern. Most of the damage to the nigrostriatal dopamine system occurs during the presymptomatic phase of the disease an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60153a97741080d281b478d95d10adbb
https://pubmed.ncbi.nlm.nih.gov/20123555
https://pubmed.ncbi.nlm.nih.gov/20123555
Autor:
R. de la Fuente-Fernandez, Lisa Kuramoto, A. J. Stoessl, Thomas J. Ruth, Chong S. Lee, J. McKenzie, Ali Samii, Siobhan McCormick, Michael Schulzer, Donald B. Calne, André R. Troiano, Jacquelyn J. Cragg, Vesna Sossi, R. Nandhagopal, Edwin Mak
Publikováno v:
Brain : a journal of neurology. 132(Pt 11)
Parkinson's disease is a heterogeneous disorder with multiple factors contributing to disease initiation and progression. Using serial, multi-tracer positron emission tomography imaging, we studied a cohort of 78 subjects with sporadic Parkinson's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc05b66aed3eddc75571412775f93b25
https://pubmed.ncbi.nlm.nih.gov/19690093
https://pubmed.ncbi.nlm.nih.gov/19690093