Zobrazeno 1 - 10
of 350
pro vyhledávání: '"R. de Hertogh"'
Publikováno v:
Biology of Reproduction. 68:1808-1812
Previous investigations have shown that maternal diabetes impairs rodent embryo development during the earliest phase of gestation. Exposure to high concentrations of glucose before implantation results in a decrease in the number of cells per embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76e9fa05338c3a869803490e1f2d4de
https://doi.org/10.1095/biolreprod.102.010009
https://doi.org/10.1095/biolreprod.102.010009
Publikováno v:
Diabetologia. 46:276-283
Previous studies have shown that diabetic placentas are characterized by structural and biochemical anomalies, including defects in the differentiation of trophoblasts. In this study, the Rcho-1 cell line was used to investigate the impact of high gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47921b89c82c90b032ef33bbd17c3134
https://doi.org/10.1007/s00125-002-1016-1
https://doi.org/10.1007/s00125-002-1016-1
Publikováno v:
Diabetologia. 45:571-579
Aims/hypothesis. Signs of apoptosis have been observed in rodent blastocysts exposed to high d-glucose concentrations in vitro. The mechanism underlying the detrimental influence of glucose remains to be identified. It has been postulated that high d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aae169483c8470c218801c0293be970
https://doi.org/10.1007/s00125-001-0752-y
https://doi.org/10.1007/s00125-001-0752-y
Publikováno v:
Biology of Reproduction. 58:1416-1424
Previous studies have shown the adverse impact of the cytokine tumor necrosis factor alpha (TNFalpha) on the development of the inner cell mass in mouse blastocysts. In the present study, two embryonic stem (ES) cell lines were used to further invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7ce87a4d441e1df79a0b86767b2914
https://doi.org/10.1095/biolreprod58.6.1416
https://doi.org/10.1095/biolreprod58.6.1416
Publikováno v:
Scopus-Elsevier
The morphogenetic function of the transient phase of cell death that occurs during blastocyst maturation is not known but it is thought that its regulation results from a delicate balance between survival and lethal signals in the uterine milieu. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dd52291ebff031105662994d263c0e
https://doi.org/10.1242/dev.124.23.4827
https://doi.org/10.1242/dev.124.23.4827
Publikováno v:
Diabetes. 46:1214-1224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e3eac7f17c4c1353a46524c76abd3cc
https://doi.org/10.2337/diabetes.46.7.1214
https://doi.org/10.2337/diabetes.46.7.1214
Publikováno v:
Clinical Endocrinology. 44:429-433
OBJECTIVE: Pregnancy induced hypertension has been shown to be associated with a normal or low activity of the maternal circulating renin-angiotensin system (RAS) but little is known of the local RAS in placenta and fetal membranes. The present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b10edc364ae88823f6c8eebc11ae0e2
https://doi.org/10.1046/j.1365-2265.1996.703525.x
https://doi.org/10.1046/j.1365-2265.1996.703525.x
Publikováno v:
Biology of Reproduction. 52:1316-1326
Antisense oligodeoxyribonucleotide inhibition of gene expression was used to test whether the p60 form of the tumor necrosis factor alpha (TNF alpha) receptor (Rp60) is responsible for mediating the negative effect of TNF alpha on the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40f37a4120aadae8a53208cccc4fb5d
https://doi.org/10.1095/biolreprod52.6.1316
https://doi.org/10.1095/biolreprod52.6.1316
Publikováno v:
Diabetes. 44:531-536
Tumor necrosis factor (TNF) bioactivity was assessed in culture media conditioned with uterine cells collected from control or diabetic rats on days 5 and 8 of pregnancy. On both days, diabetic uterine cells released significantly more biologically a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3a1d29a59f8abf96d366f48afa3a04
https://doi.org/10.2337/diab.44.5.531
https://doi.org/10.2337/diab.44.5.531