Zobrazeno 1 - 10
of 100
pro vyhledávání: '"R. d'Argy"'
Publikováno v:
Toxicological Sciences. 43:196-203
Occupational exposure to nickel by inhalation may result in impaired olfactory sense. Recent studies have shown that nickel is transported from the olfactory epithelium along the axons of the primary olfactory neurons to the brain. In the present stu
Autor:
Antonino Suarato, R d’Argy, A Fiorino, A Ghiglieri, Francesco Angelucci, Moreno Zamai, Enrico Frigerio, M. G. Castelli, Valeria R. Caiolfa, Enrico Pesenti, M Farao, M. Gigli, C. Pellizzoni
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 65(1-2)
Camptothecin (CPT) is a potent, antitumour drug acting mainly through inhibition of topoisomerase I during the S-phase of the cell cycle. Despite its impressive antitumour activity, clinical development was halted for unpredictable toxic events. Two
Publikováno v:
European journal of cancer (Oxford, England : 1990). (10)
Tumour uptake of a radiolabelled anticancer drug, tauromustine ([14C]TCNU), was investigated, using two different routes of administration in rats with colon adenocarcinomas implanted in the liver. Intra-arterial administration produced higher concen
Publikováno v:
Oncology research. 6(12)
In vivo binding of [3H]-PK 11195 to peripheral benzodiazepine binding sites in Dunning AT-1 prostatic tumour-bearing rats was investigated by whole-body autoradiography. Distribution and retention of PK 11195 in tumour and other organs was examined a
Autor:
S.S. Jossan, P.G. Gillberg, R. d'Argy, S.M. Aquilonius, B. Låangstro¨m, C. Halldin, L. Oreland
Publikováno v:
Brain research. 547(1)
The distribution of monoamine oxidase B (MAO-B) in the human brain was studied by quantitative autoradiography using l -[ 3 H]deprenyl as a ligand. Two postmortem brains from patients without any known neurological diseases were used in this study. C
Publikováno v:
Acta radiologica. Supplementum. 376
Autor:
J. R. Barrio, D. C. Sigee, S. Ullberg, R. d'Argy, R. Ekins, B. S. Larsson, E. Randerath, X. Wang, T. Qu, L. Dencker, R. D. Vis, Y. Liu, K. Randerath, H. Tjalve, K. S. Kasprzak, F. Parak
Publikováno v:
Pure and Applied Chemistry. 63:1269-1270
Covalent binding of chemicals or their metabolites to DNA is a critical event in the initiation of chemical carcinogenesis. Measurement of covalent DNA adducts in model and human systems has become an important tool in mutation and cancer research. T
Publikováno v:
Psychopharmacology. 92:8-13
3H-Ro 15-1788, a benzodiazepine receptor antagonist, was injected IV into male and pregnant mice. Autoradiograms were prepared from sagittal sections of animals killed after 30 s to 48 h. In the adult animal there was a rapid and high initial accumul
Publikováno v:
Developmental pharmacology and therapeutics. 10(3)
Retinoic acid (RA) binds to a cytosolic protein distinguishable from the cellular retinol (R) binding protein. Recent studies, showing an influence by R and RA on genomic expression, suggest an interaction with the cell nucleus mediated by the specif
Publikováno v:
Molecular pharmacology. 27(1)
Fetal thymuses from C57BL/6 (B6) and DBA/2J (D2) mice from gestation day 14 or 15 were explanted and grown for 2 and 6 days in culture in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and a number of its congeners, known ligands of the A