Scoring the tumor-stroma ratio in colon cancer: procedure and recommendations

Autor: Flemming Brandt Sørensen, G W van Pelt, Rob A. E. M. Tollenaar, J.H.J.M. van Krieken, Hans Morreau, Sanne Kjær-Frifeldt, Wilma E. Mesker, R. al Dieri

Publikováno v: Virchows Archiv
van Pelt, G W, Kjær-Frifeldt, S, van Krieken, J H J M, Al Dieri, R, Morreau, H, Tollenaar, R A E M, Sørensen, F B & Mesker, W E 2018, ' Scoring the tumor-stroma ratio in colon cancer : procedure and recommendations ', Virchows Archiv, vol. 473, no. 4, pp. 405-412 . https://doi.org/10.1007/s00428-018-2408-z
Virchows Archiv, 473, 405-412
Virchows Archiv, 473, 4, pp. 405-412
Virchows Archiv, 473(4), 405-412

The tumor-stroma ratio (TSR) has been reported as a strong, independent prognostic parameter in colon cancer as well as in other epithelial cancer types, and may be implemented to routine pathology diagnostics. The TSR is an easy technique, based on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3dd32589339d4b0f3fe5de20421fbc
https://hdl.handle.net/1887/79914

Fixed dosage of low-molecular-weight heparins causes large individual variation in coagulability, only partly correlated to body weight

Autor: H.C. Hemker, R. Al Dieri, Suzette Beguin, Susanne Alban

Publikováno v: Journal of Thrombosis and Haemostasis, 4(1), 83-89. Wiley

Summary. Backgrounds: Low-molecular-weight heparins (LMWHs) are routinely given without the control of their effect on coagulation. The endogenous thrombin potential (ETP) is a sensitive detector of the heparin effect. Question: What is the interindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5885c4334e57451fed5d9432d9d69dd3
https://cris.maastrichtuniversity.nl/en/publications/3fba0513-9ce5-468e-bc7d-09644facffa6

The inhibition of blood coagulation by heparins of different molecular weight is caused by a common functional motif

Autor: Robert Wagenvoord, G W K van Dedem, R. Al Dieri, H. C. Hemker, Suzette Beguin

Publikováno v: Journal of Thrombosis and Haemostasis, 1(5), 907-914. Wiley

Summary. Background: Heparins in clinical use differ considerably as to mode of preparation, molecular weight distribution and pharmacodynamic properties. Objectives: Find a common basis for their anticoagulant action. Methods: In 50 fractions of vir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968cdbd39b79a9de90a0a827541f775d
https://doi.org/10.1046/j.1538-7836.2003.00211.x

Monitoring new oral antithrombotics: what we should know before we can decide

Autor: H.C. Hemker, R. Al Dieri

Publikováno v: Journal of Thrombosis and Haemostasis. 8:2833-2835

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::186a2b2031c9218c7fa0877226dab11b
https://doi.org/10.1111/j.1538-7836.2010.04057.x

A new regulatory function of activated factor V: inhibition of the activation by tissue factor/factor VII(a) of factor X

Autor: Rob Wagenvoord, R. Al Dieri, Hilde Kelchtermans, H.C. Hemker, Saartje Bloemen

Publikováno v: Journal of Thrombosis and Haemostasis, 11(3), 503-511. Wiley

Summary Background We observed that minute amounts of thrombin or the enzyme Russell's viper venom activating factor V (RVV-V) added to plasma strongly diminish the potential of that plasma to generate thrombin after being triggered by tissue factor.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020a645fce374f0220cacc875521d101
https://pubmed.ncbi.nlm.nih.gov/23294934