Zobrazeno 1 - 10
of 267
pro vyhledávání: '"R. Zacharias"'
Autor:
Christopher E. Lopez, Zeb R. Zacharias, Kathleen A. Ross, Balaji Narasimhan, Thomas J. Waldschmidt, Kevin L. Legge
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Influenza A virus (IAV) causes significant morbidity and mortality worldwide due to seasonal epidemics and periodic pandemics. The antigenic drift/shift of IAV continually gives rise to new strains and subtypes, aiding IAV in circumventing p
Externí odkaz:
https://doaj.org/article/287eb466d055478badd3a682ea9675c4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Glycerol monolaurate (GML) is a naturally occurring antimicrobial agent used commercially in numerous products and food items. GML is also used as a homeopathic agent and is being clinically tested to treat several human diseases. In additio
Externí odkaz:
https://doaj.org/article/654d8d0b3ead4a838e4c1eb63b5d123e
Autor:
Amira Zaher, Laura M. Stephens, Ann M. Miller, Stacey M. Hartwig, Jeffrey M. Stolwijk, Michael S. Petronek, Zeb R. Zacharias, Thaddeus J. Wadas, Varun Monga, Joseph J. Cullen, Muhammad Furqan, Jon C. D. Houtman, Steven M. Varga, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pharmacological ascorbate (i.e., intravenous infusions of vitamin C reaching ~ 20 mM in plasma) is under active investigation as an adjuvant to standard of care anti-cancer treatments due to its dual redox roles as an antioxidant in normal tissues an
Externí odkaz:
https://doaj.org/article/ae800cab6bcd4188b2c0616a5d74bf80
Autor:
Kai J. Rogers, Paige T. Richards, Zeb R. Zacharias, Laura L. Stunz, Rahul Vijay, Noah S. Butler, Kevin L. Legge, Gail A. Bishop, Wendy Maury
Publikováno v:
Viruses, Vol 15, Iss 6, p 1353 (2023)
Macrophages are critical in the pathogenesis of a diverse group of viral pathogens, both as targets of infection and for eliciting primary defense mechanisms. Our prior in vitro work identified that CD40 signaling in murine peritoneal macrophages pro
Externí odkaz:
https://doaj.org/article/8c6c1dee7bbf437da582233b4cccd168
Autor:
Angela D. Pack, Patrick V. Schwartzhoff, Zeb R. Zacharias, Daniel Fernandez-Ruiz, William R. Heath, Prajwal Gurung, Kevin L. Legge, Chris J. Janse, Noah S. Butler
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109586- (2021)
Summary: During acute malaria, most individuals mount robust inflammatory responses that limit parasite burden. However, long-lived sterilizing anti-malarial memory responses are not efficiently induced, even following repeated Plasmodium exposures.
Externí odkaz:
https://doaj.org/article/551fd0310a5d474cbf06149feb511e75
Autor:
Maury, Kai J. Rogers, Paige T. Richards, Zeb R. Zacharias, Laura L. Stunz, Rahul Vijay, Noah S. Butler, Kevin L. Legge, Gail A. Bishop, Wendy
Publikováno v:
Viruses; Volume 15; Issue 6; Pages: 1353
Macrophages are critical in the pathogenesis of a diverse group of viral pathogens, both as targets of infection and for eliciting primary defense mechanisms. Our prior in vitro work identified that CD40 signaling in murine peritoneal macrophages pro
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Influenza A virus (IAV) is a leading cause of respiratory infections, with increased risk of severe illness and death in the very young, aged, and immunocompromised individuals. In both mice and humans, IAV-specific T cell responses are protective du
Externí odkaz:
https://doaj.org/article/1c497987147b4782aaba5c53e1d3e21c
Autor:
Zeb R. Zacharias, Kathleen A. Ross, Emma E. Hornick, Jonathan T. Goodman, Balaji Narasimhan, Thomas J. Waldschmidt, Kevin L. Legge
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza A virus (IAV) is a major cause of respiratory illness. Given the disease severity, associated economic costs, and recent appearance of novel IAV strains, there is a renewed interest in developing novel and efficacious “universal” IAV va
Externí odkaz:
https://doaj.org/article/35d155b9836c4a4a847e5cae98b816d5
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Natural killer (NK) cells are vital components of the antiviral immune response, but their contributions in defense against influenza A virus (IAV) are not well understood. To better understand NK cell responses during IAV infections, we examined the
Externí odkaz:
https://doaj.org/article/bcd3cd25370e48628a9a6acbdc8fb849
Publikováno v:
The Journal of the Acoustical Society of America. 153:A370-A370
Laryngeal high-speed videoendoscopy (HSV) is a powerful tool to study the detailed vibratory characteristics of the vocal folds. The use of HSV in connected speech enables us to study the transitory behaviors of the vocal folds during different vocal