Zobrazeno 1 - 10
of 157
pro vyhledávání: '"R. Woodrow Setzer"'
Autor:
Zachary Stanfield, R. Woodrow Setzer, Victoria Hull, Risa R. Sayre, Kristin K. Isaacs, John F. Wambaugh
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology. 32:833-846
Publikováno v:
Journal of Statistical Software, Vol 79, Iss 1, Pp 1-26 (2017)
Thousands of chemicals have been profiled by high-throughput screening programs such as ToxCast and Tox21; these chemicals are tested in part because most of them have limited or no data on hazard, exposure, or toxicokinetics. Toxicokinetic models ai
Externí odkaz:
https://doaj.org/article/d0f38d71a0bb4c80b1e23e1196fb56fd
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215906 (2019)
Many parameters treated as constants in traditional physiologically based pharmacokinetic models must be formulated as time-varying quantities when modeling pregnancy and gestation due to the dramatic physiological and anatomical changes that occur d
Externí odkaz:
https://doaj.org/article/bc4ce670caa848b3adefdb2dcb404470
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology.
Autor:
Akshay Badrinarayanan, Robert G. Pearce, Jon Gilbert, R. Woodrow Setzer, Barbara A. Wetmore, Derek Angus, Russell S. Thomas, Teresa Sierra, Gregory S. Honda, Roger Dinallo, John F. Wambaugh, Bradley Snodgrass, Chantel I. Nicolas, Chris Strock, Adam Brockman, Caroline Ring
Publikováno v:
Toxicol Sci
High(er) throughput toxicokinetics (HTTK) encompasses in vitro measures of key determinants of chemical toxicokinetics and reverse dosimetry approaches for in vitro-in vivo extrapolation (IVIVE). With HTTK, the bioactivity identified by any in vitro
Autor:
Keith A. Houck, Alicia M. Frame, Rebecca C. Dzubow, Michael J. Stewart, Thomas F. Bateson, Daniel A. Axelrad, Julie W. Fitzpatrick, R. Woodrow Setzer, Michael J. DeVito, Karen A. Hogan
Publikováno v:
Hum Ecol Risk Assess
The Reference Dose (RfD) and Reference Concentration (RfC) are human health reference values (RfVs) representing exposure concentrations at or below which there is presumed to be little risk of adverse effects in the general human population. The 200
Autor:
Ly, Ly Pham, Sean, Watford, Prachi, Pradeep, Matthew T, Martin, Russell, Thomas, Richard, Judson, R Woodrow, Setzer, Katie, Paul Friedman
Publikováno v:
Comput Toxicol
New approach methodologies (NAMs) for chemical hazard assessment are often evaluated via comparison to animal studies; however, variability in animal study data limits NAM accuracy. The US EPA Toxicity Reference Database (ToxRefDB) enables considerat
Autor:
R. Woodrow Setzer, Logan J. Everett, Johanna Nyffeler, Joshua A. Harrill, Derik E. Haggard, Richard S. Judson, Katie Paul-Friedman, Clinton Willis
Publikováno v:
SLAS Discov
Phenotypic profiling assays are untargeted screening assays that measure a large number (hundreds to thousands) of cellular features in response to a stimulus and often yield diverse and unanticipated profiles of phenotypic effects, leading to challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bb613f20d28de40e24f34b6bfd4628
https://europepmc.org/articles/PMC8673120/
https://europepmc.org/articles/PMC8673120/
Autor:
Harrill, Joshua, Willis, Clinton, Malcomber, Sophie, White, Andy, Thomas, Russell S., Sipes, Nisha, R. Woodrow Setzer
Poster prepared for the Society of Toxicology annual meeting March 2020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aabc573d0a3aee951ea0c0b30ee8548
Autor:
Everett, Logan J., Harrill, Joshua, Haggard, Derik, Shah, Imran, Judson, Richard, Sheffield, Thomas, R. Woodrow Setzer
Poster to be presented to the Society of Toxicology annual meeting March 2020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5ee5e9beaab812ebf78fccf88d0130