Zobrazeno 1 - 10
of 148
pro vyhledávání: '"R. William. G. Watson"'
Autor:
Yie Roei Chee, R William G Watson, James McCarthy, Jehan Zeb Chughtai, Lars Nölke, David G Healy
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Background Previous studies from our group demonstrated the anti-inflammatory properties of statins on cardiopulmonary bypass (CPB), through inhibition of neutrophil transendothelial migration. We sought to determine the utility of preoperat
Externí odkaz:
https://doaj.org/article/c8919bb615864e7eaf85c67f98ba112b
Autor:
Agnieszka Krzyzanowska, Stephen Barron, Debra F. Higgins, Tony Loughman, Katherine M. Sheehan, Angel Chan-Ju Wang, Bozena Fender, Leah M. McGuire, David Galvin, Amanda O'Neil, Joanna Fay, Anthony O'Grady, Desmond O'Leary, R. William. G. Watson, Anders Bjartell, William M. Gallagher
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab3a1e084eabfe100583bc4f18228dd
https://doi.org/10.1097/ju.0000000000003237.08
https://doi.org/10.1097/ju.0000000000003237.08
Autor:
Emma R. Dorris, Helmut Klocker, Omri Teltsh, Ann Treacy, Amanda O'Neill, Elaine W. Kay, R. William G. Watson
Publikováno v:
Oncotarget
Metastatic prostate cancer is treated with androgen ablation therapy but progress to castrate resistant prostate cancer (CRPC). This study aimed to investigate the role of CUX1 in CRPC using clinical samples and in vitro models. CUX1 expression was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c4f28b058cd36381ca5df14c1b27f1
https://doi.org/10.18632/oncotarget.27494
https://doi.org/10.18632/oncotarget.27494
Autor:
Husvinee Sundaramurthi, Breandán N. Kennedy, Simone Marcone, Josep M. Piulats, Sandra García-Mulero, R. William G. Watson, Desmond J. Tobin, Lasse Jensen, Kayleigh Slater
Metastatic uveal melanoma (MUM) is characterized by poor patient survival. Unfortunately, current treatment options demonstrate limited benefits. In this study, we evaluate the efficacy of ACY-1215, a histone deacetylase 6 inhibitor (HDAC6i), to atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0afb24c34ea8b5f7f55b3b864212ee6
https://doi.org/10.1101/2021.10.28.466226
https://doi.org/10.1101/2021.10.28.466226
Autor:
Grace Callagy, Desmond Leddin, R. William G. Watson, Hilary Humphreys, Louise Burke, Mary Toner, Niall T. Stevens
Publikováno v:
Journal of Clinical Pathology. 73:47-50
Pathology is the study of disease and is an important component in medical education. However, with medical curriculum reform, its role and contribution to medical courses is under potential threat. We surveyed the status of pathology in all six Iris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3d8bd5e6080194af893d44612d99ab
https://doi.org/10.1136/jclinpath-2019-206033
https://doi.org/10.1136/jclinpath-2019-206033
Autor:
R. William G. Watson, Anders Bjartell, Rebecka Hellsten, Alexander Gaber, Felicia Elena Marginean, Nicholas Don-Doncow, Agnieszka Krzyzanowska
Publikováno v:
The Prostate. 79:784-797
Background: The signal transducer and activator of transcription 3 (STAT3) pathway is observed to be constitutively activated in several malignancies including prostate cancer (PCa). In the present study, we investigated the expression of total STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1370ad1ff0d5151bb1c65ba60c8c500c
https://doi.org/10.1002/pros.23787
https://doi.org/10.1002/pros.23787
Autor:
Stephen P. Finn, Claudia Aura, Patrick Jackman, Susan McKeever, Tiarnan Murphy, R. William G. Watson, Nebras Al-Attar, Elaine W. Kay, Amanda O'Neill, Trevor Doherty, Aoife Gowen, William M. Gallagher, Arman Rahman
Publikováno v:
Articles
The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of life and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e0d48980ff9b43ddb7336a7c947fb9
https://pubmed.ncbi.nlm.nih.gov/34060548
https://pubmed.ncbi.nlm.nih.gov/34060548
Autor:
Shirin Moghaddam, Kristin Austlid Taskén, Helmut Klocker, R. William G. Watson, Amanda O'Neill, Viktor Berge, Lisa N. Murphy, Anne-Marie Reilly, Richard E. Power, Laura Gorman, K.J. O’Malley, T. Brendan Murphy, Amirhossein Jalali, Thomas H. Lynch, Vivi-Ann Solhaug, Áine Heffernan
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4162, p 4162 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4162, p 4162 (2021)
Volume 13
Issue 16
Simple Summary Treatment decisions represent a significant dilemma for patients diagnosed with prostate cancer. The prediction of early treatment failure would inform appropriate decision making and allow the clinician and patient to consider appropr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ace0f562698b0b343d0dc005f282de
http://hdl.handle.net/10852/90597
http://hdl.handle.net/10852/90597
Autor:
Steven G. Gray, Orla Sheils, Ove Andrén, Jessica Carlsson, Danielle C. Costigan, Stephen P. Finn, Pierre Murchan, Anne-Marie Baird, Lauren Brady, Tatjana Vlajnic, David Cormican, Amanda O'Neill, R. William G. Watson, Orla Casey
Publikováno v:
Cancer Treatment and Research Communications, Vol 29, Iss, Pp 100451-(2021)
Introduction Prostate cancer is a heterogeneous disease, with a complex molecular landscape that evolves throughout disease progression. Common alterations in genes such as ERG and PTEN have been attributed to worse prognosis. This study aimed to fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196726ab94be6f6497e5187fbde198c5
http://www.sciencedirect.com/science/article/pii/S2468294221001489
http://www.sciencedirect.com/science/article/pii/S2468294221001489
Autor:
Shirin Moghaddam, Thaisa A. Baldo, Ramez Andrawis, Norman H. Lee, Ronaldo C. Faria, Dipak K. Dey, Mohamed Sharafeldin, Colleen E. Krause, James F. Rusling, Abby L Jones, R. William G. Watson, Lasangi Dhanapala, Min Shen
Publikováno v:
Analytical chemistry. 93(2)
The inability to distinguish aggressive from indolent prostate cancer is a longstanding clinical problem. Prostate specific antigen (PSA) tests and digital rectal exams cannot differentiate these forms. Because only ∼10% of diagnosed prostate cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72eed0f22b041d2666beb48a2ecb5401
https://pubmed.ncbi.nlm.nih.gov/33289381
https://pubmed.ncbi.nlm.nih.gov/33289381