Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R. William Broadhurst"'
Autor:
Muzaffar Ali, R William Broadhurst
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57345 (2013)
The STAR protein family member Quaking is essential for early development in vertebrates. For example, in oligodendrocyte cells it regulates the splicing, localization, translation and lifetime of a set of mRNAs that code for crucial components of my
Externí odkaz:
https://doaj.org/article/fa7fe33cebf24316a1c32ac6888661de
Publikováno v:
Chemical Communications (Cambridge, England)
Interaction studies show that KR domains possess a generic binding site for ACP domains and provide evidence that the 5′-phosphopantetheine prosthetic group plays a key role in delivering acyl substrates to the active site in the correct orientatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60a58962a6f0cb79d126ee5c4750d315
https://pubmed.ncbi.nlm.nih.gov/28980673
https://pubmed.ncbi.nlm.nih.gov/28980673
Autor:
Grecia M, Gonzalez, Steven W, Hardwick, Sarah L, Maslen, J Mark, Skehel, Erik, Holmqvist, Jörg, Vogel, Alex, Bateman, Ben F, Luisi, R William, Broadhurst
Publikováno v:
RNA (New York, N.Y.). 23(5)
The protein ProQ has recently been identified as a global small noncoding RNA-binding protein in Salmonella, and a similar role is anticipated for its numerous homologs in divergent bacterial species. We report the solution structure of Escherichia c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c7f321797dc21ac69ccf441ce6faf14
https://pubmed.ncbi.nlm.nih.gov/28193673
https://pubmed.ncbi.nlm.nih.gov/28193673
Publikováno v:
Chemical communications (Cambridge, England). 52(54)
An in vitro model system based on a ketosynthase domain of the erythromycin polyketide synthase was used to probe the apparent substrate tolerance of ketosynthase domains of the mycolactone polyketide synthase. A specific residue change was identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e27d072cbe0e17aa12d5d9b6e81df850
https://pubmed.ncbi.nlm.nih.gov/27307197
https://pubmed.ncbi.nlm.nih.gov/27307197
Publikováno v:
Nucleic Acids Research
In many bacterial species, the multi-enzyme RNA degradosome assembly makes key contributions to RNA metabolism. Powering the turnover of RNA and the processing of structural precursors, the RNA degradosome has differential activities on a spectrum of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a08240bf78c7c5ab1ec019b7d08202d
https://doi.org/10.1093/nar/gkq928
https://doi.org/10.1093/nar/gkq928
Autor:
Carsten D. Richter, Ricardo Núñez Miguel, Martin C. Moncrieffe, R. William Broadhurst, Kira J. Weissman, David A. Stanmore, Filip Meersman, Lucky Tran, Suzanne C Brewerton
Publikováno v:
FEBS Journal. 274:2196-2209
Domains within the multienzyme polyketide synthases are linked by noncatalytic sequences of variable length and unknown function. Recently, the crystal structure was reported of a portion of the linker between the acyltransferase (AT) and ketoreducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11b2b8f87cc4e298cf18cb44f739197
https://doi.org/10.1111/j.1742-4658.2007.05757.x
https://doi.org/10.1111/j.1742-4658.2007.05757.x
Publikováno v:
FEBS Journal. 272:259-268
A 15N-labelled peripheral-subunit binding domain (PSBD) of the dihydrolipoyl acetyltransferase (E2p) and the dimer of a solubilized interface domain (E3int) derived from the dihydrolipoyl dehydrogenase (E3) were used to investigate the basis of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2294d85cd3ec3f5171e49bea8030a7
https://doi.org/10.1111/j.1432-1033.2004.04405.x
https://doi.org/10.1111/j.1432-1033.2004.04405.x
Publikováno v:
Journal of Medicinal Chemistry. 47:4975-4978
1H NMR spectroscopy of a fluoroamantadine ligand was used to probe the pH dependence of binding to the transmembrane peptide fragment of the influenza A M2 proton channel (M2TM) incorporated into 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca79d62d313c1a671b007f3de92db654
https://doi.org/10.1021/jm0496685
https://doi.org/10.1021/jm0496685
Publikováno v:
Journal of Molecular Biology. 314:773-787
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a47ba3b1d1cf77ca7f0b90781ae4a1
https://doi.org/10.1006/jmbi.2001.5181
https://doi.org/10.1006/jmbi.2001.5181
Autor:
Richard N. Perham, Gabriel Padrón, Anabel Alvarez, Andrew R. C. Raine, Kaeko Tozawa, Gerardo Guillén, Christopher Fuller, R. William Broadhurst
Publikováno v:
European Journal of Biochemistry. 268:4908-4917
3The antigenic P64K protein from the pathogenic bacterium Neisseria meningitidis is found in the outer membrane of the cell, and consists of two parts: an 81-residue N-terminal region and a 482-residue C-terminal region. The amino-acid sequence of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7ddf4195798f0b8b64d9d249a6a70d
https://doi.org/10.1046/j.0014-2956.2001.02422.x
https://doi.org/10.1046/j.0014-2956.2001.02422.x