Zobrazeno 1 - 10
of 1 026
pro vyhledávání: '"R. Wendt"'
Autor:
Kritika Singh, Frank R. Wendt
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The internalizing spectrum encompasses a subset of psychopathologies characterized by emotional liability, anhedonia, anxiousness, distress, and fear, and includes, among others, diagnoses of major depressive disorder (MDD), generalized anxi
Externí odkaz:
https://doaj.org/article/d96696ecc0664a3e823339866c64575d
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)
Abstract To investigate the polygenicity of complex traits in populations of East Asian (EAS) and European (EUR) descents, we leveraged genome-wide data from Biobank Japan, UK Biobank, and FinnGen cohorts. Specifically, we analyzed up to 215 outcomes
Externí odkaz:
https://doaj.org/article/f86028752fcf49ceb8859e8addeb05e0
Autor:
Max S. Overshiner, Shuyuan Tian, Kegan B. Morrow, Jailyn R. Wendt, John Zhou, Hannah M. Briggs, Gerardo B. Márquez, Kathleen V. Kilway, Shin A. Moteki
Publikováno v:
Organic Materials, Vol 05, Iss 02, Pp 158-165 (2023)
Abstract Establishing a strategy for realizing programmed self-assembly is critical in manufacturing materials with functional hybrid structures. In this work, we introduce a robust methodology for enabling multi-component self-assembly using the co
Externí odkaz:
https://doaj.org/article/6b17ef77ee4e4fdc9d3862a29caa6efc
Autor:
Frank R. Wendt, Gita A. Pathak, Jacqueline Vahey, Xuejun Qin, Dora Koller, Brenda Cabrera-Mendoza, Angela Haeny, Kelly M. Harrington, Nallakkandi Rajeevan, Linh M. Duong, Daniel F. Levey, Flavio De Angelis, Antonella De Lillo, Tim B. Bigdeli, Saiju Pyarajan, VA Million Veteran Program, John Michael Gaziano, Joel Gelernter, Mihaela Aslan, Dawn Provenzale, Drew A. Helmer, Elizabeth R. Hauser, Renato Polimanti, Department of Veteran Affairs Cooperative Study Program (#2006)
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-11 (2023)
Abstract Background The Million Veteran Program (MVP) participants represent 100 years of US history, including significant social and demographic changes over time. Our study assessed two aspects of the MVP: (i) longitudinal changes in population di
Externí odkaz:
https://doaj.org/article/6ab68fd2ef8e414f81ed87df3301fd65
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
BackgroundDeath by suicide is one of the leading causes of death among adolescents. Genome-wide association studies (GWAS) have identified loci that associate with suicidal ideation and related behaviours. One such group of loci are the six contactin
Externí odkaz:
https://doaj.org/article/19494bcacd094817b033a8be09de0979
Autor:
Flavio De Angelis, Oana A. Zeleznik, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Antonella De Lillo, Dora Koller, Brenda Cabrera-Mendoza, Royce E. Clifford, Adam X. Maihofer, Caroline M. Nievergelt, Gary C. Curhan, Sharon G. Curhan, Renato Polimanti
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although seve
Externí odkaz:
https://doaj.org/article/c7fd3a7ef2844b3a9c35dc2580c0a384
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
In UK Biobank exomes, the authors identified de novo mutations in tandem repeat loci. On the population level, these tandem repeats confer large effects on several trait domains including biomarkers, anthropometrics, and tissue microstructures.
Externí odkaz:
https://doaj.org/article/cdd51cc22a214f1f9c26aaa215f460da
Autor:
Dora Koller, Frank R. Wendt, Gita A. Pathak, Antonella De Lillo, Flavio De Angelis, Brenda Cabrera-Mendoza, Serena Tucci, Renato Polimanti
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Introgression from extinct Neanderthal and Denisovan human species has been shown to contribute to the genetic pool of modern human populations and their phenotypic spectrum. Evidence of how Neanderthal introgression shaped the ge
Externí odkaz:
https://doaj.org/article/a36682a6dd7243af8337ce727917b071
Autor:
Jongmin Lee, Roger Ding, Justin Christensen, Randy R. Rosenthal, Aaron Ison, Daniel P. Gillund, David Bossert, Kyle H. Fuerschbach, William Kindel, Patrick S. Finnegan, Joel R. Wendt, Michael Gehl, Ashok Kodigala, Hayden McGuinness, Charles A. Walker, Shanalyn A. Kemme, Anthony Lentine, Grant Biedermann, Peter D. D. Schwindt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Cold-atom interferometers have been miniaturized towards fieldable quantum inertial sensing applications. Here the authors demonstrate a compact cold-atom interferometer using microfabricated gratings and discuss the possible use of photonic integrat
Externí odkaz:
https://doaj.org/article/7f08e16046ab4fc68d67cae36d5f554a
Autor:
Flavio De Angelis, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Joel Gelernter, Renato Polimanti
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Alcohol drinking and tobacco smoking are hazardous behaviors associated with a wide range of adverse health outcomes. In this study, we explored the association of polygenic risk scores (PRS) related to drinks per week, age of smoking initia
Externí odkaz:
https://doaj.org/article/0c33d29b495346df95b44cbea68f5ccb