Zobrazeno 1 - 10
of 183
pro vyhledávání: '"R. Wende"'
Autor:
Justin M. Quiles, Mark E. Pepin, Sini Sunny, Sandeep B. Shelar, Anil K. Challa, Brian Dalley, John R. Hoidal, Steven M. Pogwizd, Adam R. Wende, Namakkal S. Rajasekaran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Although recent advances in the treatment of acute coronary heart disease have reduced mortality rates, few therapeutic strategies exist to mitigate the progressive loss of cardiac function that manifests as heart failure. Nuclear factor, er
Externí odkaz:
https://doaj.org/article/0bacb871034845faa009f27435e581fe
Autor:
Christian Riehle, Jan-Thorben Sieweke, Sayan Bakshi, Chae-Myeong Ha, Nanna Louise Junker Udesen, Ole K. Møller-Helgestad, Natali Froese, Hanne Berg Ravn, Heike Bähre, Robert Geffers, Roland Seifert, Jacob E. Møller, Adam R. Wende, Johann Bauersachs, Andreas Schäfer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCardiogenic shock (CS) alters whole body metabolism and circulating biomarkers serve as prognostic markers in CS patients. Percutaneous ventricular assist devices (pVADs) unload the left ventricle by actively ejecting blood into the aorta.
Externí odkaz:
https://doaj.org/article/e8343c6376ea4bfdae12bd413e98bf54
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/4e82bc812ae245839eb79152cd77315c
Publikováno v:
Physiological Reports, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Stromal interaction molecule 1 (STIM1) is a major regulator of store‐operated calcium entry in non‐excitable cells. Recent studies have suggested that STIM1 plays a role in pathological hypertrophy; however, the physiological role of STI
Externí odkaz:
https://doaj.org/article/dd96fa0452b54f8c8ca4b8127bf5f810
Autor:
Luyun Zou, Helen E. Collins, Martin E. Young, Jianhua Zhang, Adam R. Wende, Victor M. Darley-Usmar, John C. Chatham
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) is associated with the regulation of numerous cellular processes. Despite the importance of O-GlcNAc in mediating cellular function our understanding of the mechanisms that re
Externí odkaz:
https://doaj.org/article/a648893843224187b7c6bc5d1b5885b7
Autor:
Lea Naasner, Natali Froese, Winfried Hofmann, Paolo Galuppo, Christopher Werlein, Ivanna Shymotiuk, Malgorzata Szaroszyk, Sergej Erschow, Georgios Amanakis, Heike Bähre, Mark P. Kühnel, Danny D. Jonigk, Robert Geffers, Roland Seifert, Melanie Ricke-Hoch, Adam R. Wende, William S. Blaner, E. Dale Abel, Johann Bauersachs, Christian Riehle
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H1352-H1364
Perturbed vitamin-A metabolism is associated with type 2 diabetes and mitochondrial dysfunction that are pathophysiologically linked to the development of diabetic cardiomyopathy (DCM). However, the mechanism, by which vitamin A might regulate mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e385498374878f0aed1f27acb704f6
https://doi.org/10.1152/ajpheart.00514.2022
https://doi.org/10.1152/ajpheart.00514.2022
Autor:
Manoja K. Brahma, Chae‐Myeong Ha, Mark E. Pepin, Sobuj Mia, Zhihuan Sun, John C. Chatham, Kirk M. Habegger, Evan Dale Abel, Andrew J. Paterson, Martin E. Young, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxid
Externí odkaz:
https://doaj.org/article/0690fe8d35c040cc85c04ea9e3298c31
Autor:
Mark E. Pepin, Christoph Koentges, Katharina Pfeil, Johannes Gollmer, Sophia Kersting, Sebastian Wiese, Michael M. Hoffmann, Katja E. Odening, Constantin von zur Mühlen, Philipp Diehl, Peter Stachon, Dennis Wolf, Adam R. Wende, Christoph Bode, Andreas Zirlik, Heiko Bugger
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. Here, we aime
Externí odkaz:
https://doaj.org/article/d0270a67460e4aefab542488ea2e765b
Autor:
Xiaosen Ouyang, Sayan Bakshi, Gloria A. Benavides, Zhihuan Sun, Gerardo Hernandez‐Moreno, Helen E. Collins, Mariame S. Kane, Silvio Litovsky, Martin E. Young, John C. Chatham, Victor Darley‐Usmar, Adam R. Wende, Jianhua Zhang
Publikováno v:
Physiological Reports. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4198eaf7c42406ba7dea267bfe02609
https://doi.org/10.14814/phy2.15686
https://doi.org/10.14814/phy2.15686
Autor:
Ivanna Shymotiuk, Natali Froese, Christopher Werlein, Lea Naasner, Malgorzata Szaroszyk, Mark P. Kühnel, Danny D. Jonigk, William S. Blaner, Adam R. Wende, E. Dale Abel, Johann Bauersachs, Christian Riehle
Publikováno v:
Frontiers in Endocrinology. 14
BackgroundPerturbed mitochondrial energetics and vitamin A (VitA) metabolism are associated with the pathogenesis of diet-induced obesity (DIO) and type 2 diabetes (T2D).MethodsTo test the hypothesis that VitA regulates tissue-specific mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa031fa5e93415949c2deec29a0cfe1
https://doi.org/10.3389/fendo.2023.1118751
https://doi.org/10.3389/fendo.2023.1118751