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Prenatal Toxicity of Inhaled Polymeric Methylenediphenyl Diisocyanate (MDI) Aerosols in Pregnant Wistar Rats

Autor: R. W. Tyl, J. Hellwig, A. O. Gamer, J. E. Doe

Publikováno v: Toxicological Sciences. 54:431-440

Mated Wistar rats, 25/group, were exposed to polymeric methylenediphenyl diisocyanate (MDI) aerosol of respirable size for 6 h/day, on gestational days (gd) 6 through 15, at 0, 1, 4, and 12 mg/m3. Maternal clinical signs, body weights, and feed and w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20478ceab7c65da155d6962250f86a21
https://doi.org/10.1093/toxsci/54.2.431

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Developmental Toxicity Evaluation of Methyl Tertiary‐butyl Ether (MTBE) by Inhalation in Mice and Rabbits

Autor: R. W. Tyl, R. D. Panson, T. L. Neeper-Bradley, Larry S. Andrews, C. Bevan, L. C. Fisher, J. F. Douglas

Publikováno v: Journal of Applied Toxicology. 17:S21-S29

Pregnant CD-1 mice (30 per group) and female New Zealand White rabbits (15 per group) were exposed by inhalation to 0, 1000, 4000 and 8000 ppm methyl tertiary-butyl ether (MTBE) vapor for 6 h a day during gestational days (GD) 6-15 and 6-18, respecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d57e4b19761b129adcd0820e9f2e278
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+3.3.co

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Two-generation Reproductive Toxicity Study of Methyl Tertiary-butyl Ether (MTBE) in Rats

Autor: C. Bevan, L. C. Fisher, T. L. Neeper-Bradley, J. J. Kneiss, R. D. Panson, R. W. Tyl, Larry S. Andrews

Publikováno v: Journal of Applied Toxicology. 17:S13-S19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5793e4bafd8746c46ab49adb70b17457
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+3.0.co

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Developmental Toxicity Study in Fischer 344 Rats by Whole-body Exposure toN,N-Dimethylethanolamine Vapor

Autor: Hon-Wing Leung, Dennis R. Klonne, Bryan Ballantyne, R. W. Tyl

Publikováno v: Journal of Applied Toxicology. 16:533-538

Timed-pregnant Fischer 344 rats were exposed whole body to N,N-dimethylethanolamine vapor for 6 h per day on gestational days 6-15 at mean (+/- SD) analytically measured concentrations of 10.4 +/- 0.86, 29.8 +/- 2.14 and 100 +/- 4.9 ppm. Dams were sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::465c08adcf86e3bdaebc4416f9ba381e
https://doi.org/10.1002/(sici)1099-1263(199611)16:6<533::aid-jat391>3.0.co

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Assessment of the Developmental Toxicity of Ethylene Glycol Applied Cutaneously to CD-1 Mice

Autor: L. C. Fisher, Patricia E. Losco, MA Vrbanic, R. W. Tyl, MF Kubena

Publikováno v: Fundamental and Applied Toxicology. 27:155-166

Assessment of the Developmental Toxicity of Ethylene Glycol Applied Cutaneously to CD-1 Mice. Tyl, R. W., Fisher, L. C., Kubena, M. F., Vrbanic, M. A., and Losco, P. E. (1995). Fundam. Appl. Toxicol. 27, 155-166. Ethylene glycol (EG; CAS No. 107-21-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875f0d4c66c63932e4c6c0399b553f69
https://doi.org/10.1006/faat.1995.1120

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Evaluation of the Developmental Toxicity of Ethylene Glycol Aerosol in CD-1 Mice by Nose-Only Exposure

Autor: Bryan Ballantyne, I. M. Pritts, R. W. Tyl, Dennis R. Klonne, Darol E. Dodd, L. C. Fisher, Patricia E. Losco, D. L. Fait

Publikováno v: Toxicological Sciences. 27:49-62

Ethylene glycol (EG; CAS No. 107-21-1) is teratogenic to mice by whole-body (WB) exposure to aerosol (1000-2500 mg/m3). The WB results were confounded by possible exposure from ingestion after grooming and/or from percutaneous absorption. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752bb1a0f57f517b16a37c24913770fa
https://doi.org/10.1093/toxsci/27.1.49

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