Zobrazeno 1 - 10
of 15
pro vyhledávání: '"R. W. Peck"'
Autor:
R. W. Peck, Ashraf M. El-Sayed, Justin Cappadonna, L. M. Manning, Lloyd D. Stringer, David M. Suckling
Publikováno v:
Journal of Chemical Ecology. 34:1602-1609
Disruption of Argentine ant trail following and reduced ability to forage (measured by bait location success) was achieved after presentation of an oversupply of trail pheromone, (Z)-9-hexadecenal. Experiments tested single pheromone point sources an
Publikováno v:
European Journal of Clinical Pharmacology. 53:229-234
This study investigated potential pharmacokinetic or pharmacodynamic interactions between the novel anti-migraine compound zolmitriptan (Zomig, formerly 311C90) and paracetamol and/or metoclopramide.In an open-label, randomised, crossover study, 15 h
Publikováno v:
British Journal of Clinical Pharmacology. 39:143-149
1. The bioavailability and disposition of 882C87, an anti-varicella zoster virus (VZV) agent, have been investigated in healthy young and elderly volunteers. 2. The mean bioavailability of a 200 mg tablet was 21.1% in the young (range 13.3-33.0%, n =
Autor:
Paul Rolan, J Posner, B. C. Weatherley, R. W. Peck, HB Meire, T. A. H. Holdich, G. Ridout, A. J. Mercer
Publikováno v:
British Journal of Clinical Pharmacology. 37:13-20
1. Atovaquone is a potent antiprotozoal slowly and irregularly absorbed after administration as tablets to fasting volunteers. A series of studies was performed to investigate the effects of food, bile and formulation on atovaquone absorption. 2. In
Publikováno v:
Journal of Medical Virology. 41:154-157
882C87 [1-(beta-D-arabinofuranosyl)-5-propynyluracil] is a nucleoside analogue with potent and specific antiviral activity against varicella-zoster virus (VZV). The IC50 of 882C87 against VZV ranges from 0.6 to 3.8 microM. Potentially therapeutic pla
Publikováno v:
Internal medicine journal. 38(2)
Background: Older patients are potentially at risk from the effects of polypharmacy (PP) and/or drug–drug interactions. Aims: To examine the effects of a targeted patient-specific prescriber feedback programme on patients prescribed more than 19 in
Publikováno v:
Journal of chemical ecology. 27(4)
Lindgren multiple funnel traps were set up in pine forests of central Oregon to determine the response of scolytid bark beetles to ethanol and 4-allylanisole (4AA). Traps were baited with two release rates of ethanol (4.5 or 41.4 mg/hr) and three rel
Publikováno v:
The Journal of antimicrobial chemotherapy. 37(3)
Netivudine is a nucleoside analogue with potent anti-varicella zoster virus activity. We now report two open studies of the pharmacokinetics and tolerability of netivudine in doses of 50, 100 and 200 mg twice daily. In one study, healthy volunteers r
Publikováno v:
European Journal of Clinical Pharmacology. 49
447C88 (N-Heptyl-N'-(2,4 difluoro-4-6-(2(-4-(2,2 dimethylpropyl)phenyl)ethyl)phenyl)urea) is an inhibitor of human microsomal AcylCoA: Cholesterol acyltransferase (ACAT) with an IC50 of 10.2 ng.ml-1 (23 nM). It is poorly absorbed but 5 mg.kg-1.day-1
Publikováno v:
Antimicrobial agents and chemotherapy. 39(1)
882C87 is a nucleoside analog with potent, specific activity against varicella-zoster virus. It is approximately seven times as potent as acyclovir with an in vitro 50% inhibitory concentration of 1 to 2 microM. The tolerability and pharmacokinetics