Zobrazeno 1 - 10
of 80
pro vyhledávání: '"R. Vlahov"'
Autor:
Joseph A. Reddy, Melissa Nelson, Christina Dircksen, Marilynn Vetzel, Theresa Johnson, Vicky Cross, Elaine Westrick, LongWu Qi, Spencer Hahn, Hari Krishna Santhapuram, Garth Parham, Kevin Wang, Jeremy F. Vaughn, Albert Felten, Michael Pugh, June Lu, Patrick Klein, Iontcho R. Vlahov, Christopher P. Leamon
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Folate receptor (FR)-targeted small molecule drug conjugates (SMDCs) have shown promising results in early stage clinical trials with microtubule destabilizing agents, such as vintafolide and EC1456. In our effort to develop FR-targeted SMDC
Externí odkaz:
https://doaj.org/article/62cffd133d60412fb62fcc23f334889b
Autor:
Yingjuan J. Lu, Leroy W. Wheeler, II, Haiyan Chu, Paul J. Kleindl, Michael Pugh, Fei You, Satish Rao, Gabriela Garcia, Henry Y. Wu, Andre P. da Cunha, Richard Johnson, Elaine Westrick, Vicky Cross, Alex Lloyd, Christina Dircksen, Patrick J. Klein, Iontcho R. Vlahov, Philip S. Low, Christopher P. Leamon
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422- (2021)
Summary: Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar aff
Externí odkaz:
https://doaj.org/article/e2fda03da1f14baea081c09735a4dc68
Autor:
Philip S. Low, Paul J. Kleindl, Andre P. da Cunha, Satish Rao, Patrick J. Klein, Leroy W Wheeler, Henry Y. Wu, Christopher P. Leamon, Yingjuan J. Lu, Fei You, Alex Lloyd, Christina Dircksen, Chu Haiyan, Michael Pugh, Gabriela E. Garcia, Vicky Cross, Elaine Westrick, Richard J. Johnson, Iontcho R. Vlahov
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff3f0adb683c62473135f1023e5e206
http://www.sciencedirect.com/science/article/pii/S2666379121002846
http://www.sciencedirect.com/science/article/pii/S2666379121002846
Publikováno v:
Drug Delivery in Oncology: From Basic Research to Cancer Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cac602f563b80e089714ba2bd906db3
https://doi.org/10.1002/9783527634057.ch40
https://doi.org/10.1002/9783527634057.ch40
Autor:
Schunack Walter G, Dikran Krikorian, Miho Penkov, R. Vlahov, Nely Angelova, Stoyan Parushev, Pepa Mechkarova, Velichko Tarpanov
Publikováno v:
Synthetic Communications. 29:15-20
A new four-step synthesis of N-{3-[3-(l-piperidinylmethyl)-phenoxy]propyl}acetoxyacetamide hydrochloride has been performed. The key aralkyl ether was synthesized in high yield under moderate conditions. A suitable scaling up permits a bulky producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab9417538ee56e008ecf2567179c73d
https://doi.org/10.1080/00397919908085729
https://doi.org/10.1080/00397919908085729
Publikováno v:
Tetrahedron. 54:9913-9959
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f35d281583ee90a4879791eb9648f58
https://doi.org/10.1016/s0040-4020(98)00405-0
https://doi.org/10.1016/s0040-4020(98)00405-0
Autor:
Michael Z. Kagan, Iontcho R. Vlahov, Marshall M. Siegel, Robert J. Linhardt, Keiko Tabei, Ronald E. Hileman
Publikováno v:
Journal of Mass Spectrometry. 32:760-772
Electrospray ionization mass spectrometry was used in the negative ion mode to analyze complexes of sucrose octasulfate, sucrose heptasulfate and sulfated alpha-, beta- and gamma-cyclodextrins with synthetically prepared basic peptides, the basic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4640671f7451930c7ad3b1ddf05cb4a1
https://doi.org/10.1002/(sici)1096-9888(199707)32:7<760::aid-jms529>3.0.co
https://doi.org/10.1002/(sici)1096-9888(199707)32:7<760::aid-jms529>3.0.co
Publikováno v:
Journal of Carbohydrate Chemistry. 16:1-10
A highly regioselective conversion of sucrose into 6-O-acyl derivatives is reported. First sucrose was transformed into the dibutyltin acetal, thus enhancing the nucleophilicity at the C-6 oxygen and restricting the subsequent acylation reaction. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1fd974c912627ed30d54bbd93f491e3
https://doi.org/10.1080/07328309708006506
https://doi.org/10.1080/07328309708006506
Publikováno v:
Journal of Carbohydrate Chemistry. 15:351-360
The isolation of a heparan sulfate derived tetrasaccharide containing N-acetylmannosamine is described. The N-acetylmannosamine residue at the reducing terminus of heparin lyase derived tetrasaccharide is formed by base catalyzed C-2 epimerization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c91c008e6b3c97a548cddb91746095
https://doi.org/10.1080/07328309608005658
https://doi.org/10.1080/07328309608005658
Autor:
Iontcho R. Vlahov, Robert J. Linhardt
Publikováno v:
Tetrahedron Letters. 36:8379-8382
Synthesis of new and potentially universal l -idopyranuronic glycosyl-donor and/or -acceptor 13 was performed starting from d -glucofuranurono-6,3-lactone 1 . After simple C-5-epimerization, C-1thioacetalization and regioselective p -methoxybenzylide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68cb26edb152c34381b84cbe69626b3
https://doi.org/10.1016/0040-4039(95)01810-5
https://doi.org/10.1016/0040-4039(95)01810-5