Zobrazeno 1 - 10
of 106
pro vyhledávání: '"R. Verrijk"'
Publikováno v:
International journal of pharmaceutics. 596
Probabilistic modeling using influence networks is an efficient, intuitive, and easy to communicate strategy in the development of complex pharmaceutical products. This study was aimed to use a risk-based approach to explore the complex interactions
Autor:
Johan H. M. Frijns, Marcel J. Vonk, Amon R. Wafelman, Jan W. Drijfhout, Peter H. Nibbering, R. Verrijk, Ewoud J. van Hoogdalem, Nanno F. A. W. Peek, Thekla Jansen-Werkhoven, Pieter S. Hiemstra, Jan J. Grote, Ronald Brand, A. Rob P. M. Valentijn, Marja J. Nell
Publikováno v:
PLoS ONE, 15(4). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 15, Iss 4, p e0231573 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0231573 (2020)
PLoS ONE
Objective Chronic suppurative otitis media (CSOM) is a chronic infectious disease with worldwide prevalence that causes hearing loss and decreased quality of life. As current (antibiotic) treatments often unsuccessful and antibiotic resistance is eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b46e37635c0c11d8d947bc5fe8ca5da
https://hdl.handle.net/1887/3182073
https://hdl.handle.net/1887/3182073
Autor:
Andrea Sekulovic, Wim Jiskoot, Jukka Rantanen, Adam D. Grabarek, Thomas Rades, R. Verrijk, Andrea Hawe
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, 193, 113744
Journal of Pharmaceutical and Biomedical Analysis, 193, 113744
Solid form diversity of raw materials can be critical for the performance of the final drug product. In this study, Raman spectroscopy, image analysis and combined Raman and image analysis were utilized to characterize the solid form composition of a
Autor:
Wim Jiskoot, Jelte Meulenaar, M. Reza Nejadnik, R. Verrijk, Stephan K.D. Waasdorp, Ahmad S. Sediq, Miranda M. C. van Beers
The release of drugs from poly(lactic-co-glycolic acid) (PLGA) microparticles depends to a large extent on the porosity of the particles. Therefore, porosity determination of PLGA microparticles is extremely important during pharmaceutical product de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f2e99327f9259b92f4527f0b38f14
http://hdl.handle.net/1887/3202254
http://hdl.handle.net/1887/3202254
Autor:
Myrra G. Carstens, Cornelus F. van Nostrum, Leo G.J. de Leede, Daan J.A. Crommelin, R. Verrijk, Wim E. Hennink
Publikováno v:
Journal of Pharmaceutical Sciences. 97:506-518
The chemical and enzymatic degradation of monodisperse oligo(e‐caprolactone) (OCL) and its amphiphilic block oligomer with methoxy poly(ethylene glycol) (mPEG) were investigated in order to obtain insight into the degradation of mPEG‐ b ‐OCL mi
Autor:
Jan J. Grote, G. Sandra Tjabringa, Marja J. Nell, Jan W. Drijfhout, Pieter S. Hiemstra, R. Verrijk, Amon R. Wafelman
Publikováno v:
Peptides (Fayetteville, N.J.), 27, 649-60
Peptides (Fayetteville, N.J.), 27, 4, pp. 649-60
Peptides (Fayetteville, N.J.), 27, 4, pp. 649-60
Contains fulltext : 49435tjabringa.pdf (Publisher’s version ) (Open Access) New peptides for lipopolysaccharide (LPS) and lipoteichoic acid (LTA) neutralization in upper respiratory tract infections were developed and evaluated in terms of efficacy
Autor:
G. Heuff, Sung Wan Kim, S. Meijer, J. Wondergem, G. Kwon, L. G. Bayon, R. Verrijk, You Han Bae, H.F.M. Cremers, Jan Feijen, M.M. Wesseling
Publikováno v:
International journal of pharmaceutics, 120(1), 51-61. Elsevier
Adriamycin (ADR) was formulated in albumin-heparin conjugate microspheres (AHCMS) to improve site-specific delivery and to reduce the toxicity of the drug. The effect of formulating ADR in AHCMS was investigated upon intrahepatic administration to ma
Publikováno v:
Radiotherapy and Oncology. 27:46-54
Borocaptate sodium (BSH) and l -boronophenylalanine (L-BPA) are two boron carriers used for boron neutron capture therapy (BNCT) in the treatment of glioblastoma and melanoma, respectively. The suitability of these two compounds was evaluated on the
Publikováno v:
Journal of Pharmaceutical Sciences. 79:236-239
Milrinone (1,6-dihydro-2-methyl-6-oxo[3,4'-bipyridine]-5-carbonitrile) is a cardiotonic drug, currently under clinical investigation for the treatment of congestive heart failure. Its positive inotropic properties and its strong vasodilative action c
Autor:
J. H. Van Steenis, Gert Storm, E.M. van Maarseveen, R. Verrijk, Wim E. Hennink, Daan J.A. Crommelin, F.J. Verbaan
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 87(1-3)
A folate-poly(ethylene glycol) conjugate capable of covalent coupling to primary amines present at the surface of polyplexes was developed. Coating of poly(dimethylaminomethyl methacrylate (pDMAEMA)-based polyplexes with this folate-pEG conjugate led