Zobrazeno 1 - 10
of 59
pro vyhledávání: '"R. V. Srinivas"'
Publikováno v:
Vaccine. 17:1567-1572
Recombinant DNA and vaccinia virus (VV) vectors that express envelope (Env) proteins of the human immunodeficiency virus (HIV) have each been prominently utilized in vaccine development. These two vectors (termed DNA-Env and VV-Env) are attractive va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120cd6ace46e3ac0a1393197e08ad823
https://doi.org/10.1016/s0264-410x(98)00355-7
https://doi.org/10.1016/s0264-410x(98)00355-7
Autor:
Arnold Fridland, R V Srinivas
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:1484-1487
9- R -2-Phosphonomethoxypropyl adenine (PMPA) is an acyclic nucleoside phosphonate analog that has demonstrated efficacy against human immunodeficiency virus (HIV). We recently described the synthesis, metabolism, and biological activities of bis(iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2066ee6406301565a088bd17636a8535
https://doi.org/10.1128/aac.42.6.1484
https://doi.org/10.1128/aac.42.6.1484
Autor:
John S. Driscoll, Hiroaki Mitsuya, R V Srinivas, Ferdinand K. Hui, Takamasa Ueno, Masatoshi Tanaka, Mark F. Kavlick, Arnold Fridland
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:1313-1318
2'-beta-Fluoro-2',3'-dideoxyadenosine (F-ddA) is an acid-stable purine dideoxynucleoside analog active against a wide spectrum of human immunodeficiency virus type 1 (HIV-1) and HIV-2 strains in vitro. F-ddA is presently undergoing a phase I clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0da4063aa16c11d20ba17cf7166bd9c
https://doi.org/10.1128/aac.41.6.1313
https://doi.org/10.1128/aac.41.6.1313
Autor:
R V Srinivas, Ratna B. Ray
Publikováno v:
Journal of Cellular Biochemistry. 64:565-572
A cellular transcriptional factor initially identified as the c-myc promoter binding protein (MBP-1) was subsequently characterized as a cell regulatory protein with multifunctional activities. In this study, the role of MBP-1 on human immunodeficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a108047c629fb170c1d2ec5aedc64b75
https://doi.org/10.1002/(sici)1097-4644(19970315)64:4<565::aid-jcb4>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19970315)64:4<565::aid-jcb4>3.0.co
Publikováno v:
AIDS Research and Human Retroviruses. 11:1015-1021
CD43 is a cell surface sialoglycoprotein expressed by most cells of hematopoietic origin, including all T lymphocytes. Elimination of CD43 expression by gene targeting in the CEM T cell line results in its increased homotypic adhesion and binding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae3955b572178fbc681ecb8d123948b
https://doi.org/10.1089/aid.1995.11.1015
https://doi.org/10.1089/aid.1995.11.1015
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 14:641-644
Hydroxyurea (HU), - a ribonucleotide reductase inhibitor which depletes dNTP pools, inhibited HIV replication, and the extent of inhibition correlated with its antiproliferative effects. HU treatment, prior to, and during the initial 12 h of HIV infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d4f102e70ca12f15891ab387ee6d66
https://doi.org/10.1080/15257779508012441
https://doi.org/10.1080/15257779508012441
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:1683-1687
The acyclic purine nucleoside phosphonates, a newly described class of broad-spectrum antiviral agents, effectively inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro and in animal AIDS models. 9-(2-Phosphonylmethoxyethyl)adenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567b7afbc61093777abfdfee1db25cee
https://doi.org/10.1128/aac.38.7.1683
https://doi.org/10.1128/aac.38.7.1683
Autor:
Arnold Fridland, Craig M. McDonald, R V Srinivas, Patricia M. Flynn, Brian L. Robbins, John H. Rodman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:115-121
In this report, we describe a new method to measure intracellular zidovudine triphosphate (ZDV-TP) levels in peripheral blood mononuclear cells (PBMCs) from patients treated with ZDV by utilizing inhibition of human immunodeficiency virus type 1 reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84741738b16e40be7f09f568d5775d2
https://doi.org/10.1128/aac.38.1.115
https://doi.org/10.1128/aac.38.1.115
Autor:
Yi-Fei Gong, N. Bischofberger, Arnold Fridland, Michele Connelly, Brian L. Robbins, R V Srinivas
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2247-2250
Bis(pivaloyloxymethyl) [bis(pom)] derivatives of various acyclic nucleoside phosphonates--9-(2-phosphonylmethoxyethyl)adenine (PMEA), 9-(2-phosphonylmethoxypropyl)adenine (PMPA), and 9-(2-phosphonylmethoxypropyl)diaminopurine (PMPDAP)--were found to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c241eae5a40cbd40afe3726decd6b083
https://doi.org/10.1128/aac.37.10.2247
https://doi.org/10.1128/aac.37.10.2247
Autor:
Gattadahalli M. Anantharamaiah, Richard W. Compans, Jere P. Segrest, S K Srinivas, R V Srinivas
Publikováno v:
Journal of Biological Chemistry. 268:22895-22899
Calmodulin (CaM), the major intracellular receptor for calcium, is involved in regulation of diverse cellular functions. Positively charged amphipathic helical segments have been identified as an important structural motif in the recognition of CaM b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aabf8f739651d88e7a770e6daa8590f
https://doi.org/10.1016/s0021-9258(18)41610-9
https://doi.org/10.1016/s0021-9258(18)41610-9