Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R. V. LaRocca"'
Autor:
McClellan M. Walther, R V LaRocca, Michael R. Cooper, M M Uhrich, P. L. Choyke, Seth M. Steinberg, Cy A. Stein, Nancy A. Dawson, G Weiss, Charles E. Myers
Publikováno v:
Journal of Clinical Oncology. 10:881-889
PURPOSE Suramin is known to inhibit the growth of malignant prostate carcinoma cells in vitro. This led us to evaluate the effectiveness of suramin in the treatment of 38 patients with prostate carcinoma refractory to hormone therapy. PATIENTS AND ME
Autor:
George H. Goldsmith, Shawn D. Glisson, R. V. Larocca, J. B. Hargis, A. Cervera, D. D. Repishti, J. E. Sunderland, B. Cornell
Publikováno v:
Journal of Clinical Oncology. 27:e15130-e15130
e15130 Background: The median overall survival (‘OS‘) for patients with mCRC treated with chemotherapy is about 20.4 months. Combination chemotherapy with surgical cytoreduction for patients with liver metastases are evaluated in a phase II clini
Autor:
J G, Park, H, Frucht, R V, LaRocca, D P, Bliss, Y, Kurita, T R, Chen, J G, Henslee, J B, Trepel, R T, Jensen, B E, Johnson
Publikováno v:
Cancer research. 50(9)
We report the establishment and characterization of four continuous cell lines derived from human primary and metastatic gastric carcinomas, and we compare their properties with a panel of colorectal carcinoma cell lines previously established and re
Publikováno v:
Journal of Clinical Oncology. 25:18005-18005
18005 Background: Cetuximab, an IgG1 monoclonal antibody targeting the epidermal growth factor receptor (EGFR) on both normal and tumor cells, has been investigated in advanced NSCLC as a single agent and in combination with chemotherapy. At the time
Autor:
R. Vassilopoulou-Sellin, B. F. Cole, A. T. Fojo, D. I. Quinn, W. K. Oh, Marc S. Ernstoff, Vincent A. Memoli, P. A. Simmons, C. P. Tretter, V. Samnotra, R. V. LaRocca
Publikováno v:
Journal of Clinical Oncology. 25:15527-15527
15527 Background: ACC is a rare malignancy with a very poor prognosis. Surgery is the only potential curative option. Gefitinib is an oral EGFR inhibitor that may have activity in solid tumors that express EGFR. ACC over expresses EGFR in a high prop
Autor:
M. J. Doyle, S. D. Glisson, T. W. Vitaz, D. J. Morassutti, A. Cervera, P. New, J. B. Hargis, L. Stribinskiene, George H. Goldsmith, R. V. Larocca
Publikováno v:
Journal of Clinical Oncology. 23:1547-1547
1547 Background: Prior studies demonstrated the effectiveness of both BCNU wafer (Gliadel) and TMZ (Temodar) as adjunctive therapies to resection and radiation therapy (RT) in pts with initial high...
Autor:
M. A. Choudry, F. J. Hendler, R. V. Larocca, L. Bhupalam, A. C. Mehta, Goetz H. Kloecker, Vivek R. Sharma, C. Crump, Damian A. Laber, Donald M. Miller
Publikováno v:
Journal of Clinical Oncology. 23:4757-4757
4708 Background: Novel and effective therapies for patients with AIPC are needed. Oral therapy offers the tremendous advantage of independence and avoids all the catheter-related complications. Cyclophosphamide, etoposide and estramustine have shown
Autor:
R. V. Larocca, A. Cervera, J. B. Hargis, S. D. Glisson, G. H. Goldsmith, M. A. M. Laureano, B. Foreman
Publikováno v:
Journal of Clinical Oncology. 22:1578-1578
Publikováno v:
Journal of Neuroscience Research. 24:97-106
Previously reported studies have suggested that variations in the pattern of proto-oncogene expression within a specific tumor type may denote an underlying difference in the biology and clinical behavior of those tumors. To more sensitively characte
Publikováno v:
Journal of Clinical Oncology. 7:499-508
We administered suramin, an anti-parasitic drug and reverse transcriptase inhibitor, to 15 patients with metastatic cancer. This compound is known to inhibit the binding of growth factors (eg, epidermal growth factor [EGF], platelet-derived growth fa