Zobrazeno 1 - 10
of 39
pro vyhledávání: '"R. V. Kondratenko"'
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 2, Iss 2, Pp 23-27 (2017)
The search for physiologically active drugs with precognitive action and the study of mechanisms of their influence on the brain represent important tasks of neurobiology and neuropharmacology. The paper considers methodical and scientific approaches
Externí odkaz:
https://doaj.org/article/b2a971df0e574a51b14bb4dd7a5beb14
Publikováno v:
Bulletin of Experimental Biology and Medicine
Ivermectin (IVM) belongs to the class of macrocyclic lactones, which is used as an antiparasitic agent. At present, the researchers focus on possibility to use IVM in treatment of certain forms of cancer and viral diseases such as COVID-19. The mecha
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:791-794
Chloride current (IGly) evoked by the rapid (600 msec) application of glycine on isolated pyramidal neurons of the rat hippocampus was recorded using the patch clamp technique. We studied the effect of individual or combined application of copper ion
Publikováno v:
Biomolecules
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Epipregnanolone (3β-hydroxy-5β-pregnan-20-one, Epi) is an endogenous steroid with important physiological effects and high affinity for GABAA receptors. The effect of Epi on GABA-induced chloride current (IGABA) in native neurons has hardly been st
Autor:
Alexander A. Kravtsov, Stanislav V. Kozin, Elena Butina, M. G. Baryshev, R. V. Kondratenko, A. V. Moiseev, S. S. Dzhimak, V. V. Malyshko, Vladimir G. Skrebitsky, A.A. Elkina
Publikováno v:
Molecules, Vol 26, Iss 2036, p 2036 (2021)
Molecules
Volume 26
Issue 7
Molecules
Volume 26
Issue 7
The deuterium content modification in an organism has a neuroprotective effect during the hypoxia model, affecting anxiety, memory and stress resistance. The aim of this work was to elucidate the possible mechanisms of the medium D/H composition modi
Autor:
R. V. Kondratenko, E. E. Genrikhs, M. R. Kapkaeva, Nickolay K. Isaev, Elena V. Stelmashook, Leonid G. Khaspekov
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 12:234-238
The dynamics of changes of spontaneous neuronal activity in primary hippocampal cell cultures developing on a multielectrode array (MEA) was studied using a multielectrode system. The intensification of bioelectrical activity, which depended on the d
Publikováno v:
Neurochemistry International. 110:69-74
We have previously shown that application of beta-amyloid peptide 1–42 (Aβ) at picomolar/nanomolar concentrations caused a decrease in the peak amplitude and acceleration of desensitization of the glycine-activated chloride current (IGly) in hippo
Autor:
Vladimir G. Skrebitsky, Leonid G. Khaspekov, Olga V. Popova, Elena V. Stelmashook, Elisaveta E. Genrikhs, P D Rogozin, M. R. Kapkaeva, Nickolay K. Isaev, R. V. Kondratenko
Publikováno v:
Experimental and Toxicologic Pathology. 69:259-264
Copper (Cu2+) is an essential metal presented in the mammalian brain and released from synaptic vesicles following neuronal depolarization. However, the disturbance of Cu2+ homeostasis results in neurotoxicity. In our study we performed for the first
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:640-642
Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontane
Publikováno v:
Bulletin of experimental biology and medicine. 167(2)
Taurine is an important endogenous agonist of glycine receptors (GlyR). Using the patchclamp technique, we measured chloride current induced by a short (600 msec) application of taurine (ITau) on isolated rat pyramidal neurons. pH of taurine solution