Výsledky vyhledávání - "R. V. Hasnadka"

Insulin increases endothelin-1-evoked intracellular free calcium responses by increased ET(A) receptor expression in rat aortic smooth muscle cells

Autor: Thomas W. Wilson, Venkat Gopalakrishnan, J. R. Mcneill, Rob L Hopfner, R. V. Hasnadka

Publikováno v: Diabetes. 47:937-944

While insulin is known to promote vascular smooth muscle (VSM) relaxation, it also enhances endothelin-1 (ET-1) secretion and action in conditions such as NIDDM and hypertension. We examined the effect of insulin pretreatment on intracellular free ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe54d2316fbd8822b1dd6ddf8c34d527
https://doi.org/10.2337/diabetes.47.6.937

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Differential Regulation of Endothelin-1 Action by Insulin and Vanadate in Vascular Smooth Muscle

Autor: Rob L Hopfner, J. R. Mcneill, Venkat Gopalakrishnan, Thomas W. Wilson, R. V. Hasnadka

Publikováno v: Journal of Cardiovascular Pharmacology. 31:S196-S198

The effects of insulin (10 nM) and sodium orthovanadate (SOV, 25 μM) pretreatment for 24 h on endothelin-l (ET-1) and IRL-1620 (ET B agonist)-evoked increases in intracellular free calcium levels [Ca 2+ ] i were determined by fura-2 fluorescence met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7c50908bb2a93718e61bbae84e559d
https://doi.org/10.1097/00005344-199800001-00055

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