Výsledky vyhledávání

Sizing DNA Using a Nanometer-Diameter Pore

Autor: Yelena V. Grinkova, Klaus Schulten, Stephen G. Sligar, Chuen Ho, Aleksij Aksimentiev, Jiunn B. Heng, Tae-Kyung Kim, Gregory Timp, R. Timp

Publikováno v: Scopus-Elsevier

Each species from bacteria to human has a distinct genetic fingerprint. Therefore, a mechanism that detects a single molecule of DNA represents the ultimate analytical tool. As a first step in the development of such a tool, we have explored using a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b223cfc4a6e4c6bf0635ac8f85a4cdc9

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Laser-guided assembly of heterotypic three-dimensional living cell microarrays

Autor: Qian Zhao, Kaethe Timp, Chun Li, Winston Timp, Paul Matsudaira, Utkur Mirsaidov, G. Timp, R. Timp, Gleb M. Akselrod

Publikováno v: Biophysical journal. 91(9)

We have assembled three-dimensional heterotypic networks of living cells in hydrogel without loss of viability using arrays of time-multiplexed, holographic optical traps. The hierarchical control of the cell positions is achieved with, to our knowle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845aedebae2e3251f33f7c958d82240c
https://pubmed.ncbi.nlm.nih.gov/16891375

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Electrolytic transport through a synthetic nanometer-diameter pore

Autor: Chuen Ho, Gregory Timp, Narayana R. Aluru, Rui Qiao, Aveek N. Chatterjee, Jiunn B. Heng, R. Timp

We have produced single, synthetic nanometer-diameter pores by using a tightly focused, high-energy electron beam to sputter atoms in 10-nm-thick silicon nitride membranes. Subsequently, we measured the ionic conductance as a function of time, bath c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36eaba8a3602989349e2d99b2f783c9
https://europepmc.org/articles/PMC1180756/

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The detection of DNA using a silicon nanopore

Autor: Yelena V. Grinkova, R. Twesten, Stephen G. Sligar, Jiunn B. Heng, V. Dimitrov, David A. Muller, T. Sorsch, Tae-Kyung Kim, R. Timp, Chuen Ho, Gregory Timp

Publikováno v: IEEE International Electron Devices Meeting 2003.

We have developed a novel strategy for producing nanopores in inorganic, CMOS-compatible membranes using a tightly focused, high energy electron beam. We are able to characterize the nanopores physically (TEM, AFM) as well as electrically (ionic cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9bed91c6176939af66c529704b617fd
https://doi.org/10.1109/iedm.2003.1269393

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Optical manipulation of silicon microparticles in biological environments

Autor: Amy L. Oldenburg, Karthy M. Kasi, Chuen Ho, Se-Jung Moon, Vladimir I. Gelfand, Tae-Kyung Kim, Hyungsoo Choi, Stephen A. Boppart, Gregory Timp, Kyekyoon Kim, Joseph T. Roland, R. Timp

Publikováno v: SPIE Proceedings.

Manipulation of micron-scale silicon particles has been investigated with optical tweezers implemented using a two-dimensional scanning trap driven with acousto-optic modulators. Spheres of latex, Poly(methyl methacrylate) (PMMA), silica, and silver-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::222527a41b228cd6e427810a2eb45d87
https://doi.org/10.1117/12.478123

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