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Akademický článek

Air quality modelling using the Met Office Unified Model (AQUM OS24-26): model description and initial evaluation

Autor: N. H. Savage, P. Agnew, L. S. Davis, C. Ordóñez, R. Thorpe, C. E. Johnson, F. M. O'Connor, M. Dalvi

Publikováno v: Geoscientific Model Development, Vol 6, Iss 2, Pp 353-372 (2013)

The on-line air quality model AQUM (Air Quality in the Unified Model) is a limited-area forecast configuration of the Met Office Unified Model which uses the UKCA (UK Chemistry and Aerosols) sub-model. AQUM has been developed with two aims: as an ope

Externí odkaz: https://doaj.org/article/7177f590c4ff4616a703ebca2fdffa41

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Akademický článek

A methodology for in-situ and remote sensing of microphysical and radiative properties of contrails as they evolve into cirrus

Autor: H. M. Jones, J. Haywood, F. Marenco, D. O'Sullivan, J. Meyer, R. Thorpe, M. W. Gallagher, M. Krämer, K. N. Bower, G. Rädel, A. Rap, A. Woolley, P. Forster, H. Coe

Publikováno v: Atmospheric Chemistry and Physics, Vol 12, Iss 17, Pp 8157-8175 (2012)

Contrails and especially their evolution into cirrus-like clouds are thought to have very important effects on local and global radiation budgets, though are generally not well represented in global climate models. Lack of contrail parameterisations

Externí odkaz: https://doaj.org/article/a6cda7c28e174035ab7e5dc276cbcf21

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Akademický článek

Circulatory HMGB1 is an early predictive and prognostic biomarker of ARDS and mortality in a swine model of polytrauma

Autor: Matthew D. Young, Tomas S. Cancio, Catherine R. Thorpe, Robert P. Willis, John K. Snook, Bryan S. Jordan, Samandra T. Demons, Jose Salinas, Zhangsheng Yang

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Acute respiratory distress syndrome (ARDS) is a leading cause of morbidity and mortality in polytrauma patients. Pharmacological treatments of ARDS are lacking, and ARDS patients rely on supportive care. Accurate diagnosis of ARDS is vital for early

Externí odkaz: https://doaj.org/article/cfead8f1b9f044cd88cce53568ad68d9

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Akademický článek

Implementing cone-beam computed tomography-guided online adaptive radiotherapy in cervical cancer

Autor: Charlotte E. Shelley, Matthew A. Bolt, Rachel Hollingdale, Susan J. Chadwick, Andrew P. Barnard, Miriam Rashid, Selina C. Reinlo, Nawda Fazel, Charlotte R. Thorpe, Alexandra J. Stewart, Chris P. South, Elizabeth J. Adams

Publikováno v: Clinical and Translational Radiation Oncology, Vol 40, Iss , Pp 100596- (2023)

Background and purpose: Adaptive radiotherapy (ART) in locally advanced cervical cancer (LACC) has shown promising outcomes. This study investigated the feasibility of cone-beam computed tomography (CBCT)-guided online ART (oART) for the treatment of

Externí odkaz: https://doaj.org/article/1b096c7e4bcf45f18831b5a43de782cd

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Akademický článek

Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): update and insights into current practices and future directions for research and implementation

Autor: Marianne A. Thrailkill, Kevin H. Gladin, Catherine R. Thorpe, Teryn R. Roberts, Jae H. Choi, Kevin K. Chung, Corina N. Necsoiu, Todd E. Rasmussen, Leopoldo C. Cancio, Andriy I. Batchinsky

Publikováno v: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 29, Iss 1, Pp 1-15 (2021)

Abstract Background In this review, we assess the state of Resuscitative Endovascular Occlusion of the Aorta (REBOA) today with respect to out-of-hospital (OOH) vs. inhospital (H) use in blunt and penetrating trauma, as well as discuss areas of promi

Externí odkaz: https://doaj.org/article/9e8f7ae47adf44959f5e2561dc6f2c8a

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The trajectory of mental health problems for UK emerging adults during COVID-19

Autor: Leslie Morrison Gutman, William J R Thorpe

Publikováno v: Journal of Psychiatric Research. 156:491-497

Initial COVID-19 restrictions were associated with declining mental health, particularly in UK emerging adults. Prior research has yet to examine changes in mental health in this demographic over the entire course of the three UK national lockdowns.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a91b56d47a465f510f67a85a90e52f
https://doi.org/10.1016/j.jpsychires.2022.10.068

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Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes

Autor: Jessica R, Thorpe, Rachel A, Wilson, Sam, Mesiano, Charles J, Malemud

Publikováno v: Open Access Rheumatology: Research and Reviews. 14:195-209

Jessica R Thorpe,1 Rachel A Wilson,2 Sam Mesiano,2 Charles J Malemud1 1Department of Medicine, Division of Rheumatic Diseases, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA; 2Department of Reproductive Biology, Case We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116ac53f40dbadd6553ce870d8404626
https://doi.org/10.2147/oarrr.s363736

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Akademický článek

A Jasmonate-Induced Defense Elicitation in Mature Leaves Reduces Carbon Export and Alters Sink Priority in Grape (Vitis vinifera Chardonnay)

Autor: Nick Gould, Michael R. Thorpe, Joe T. Taylor, Helen L. Boldingh, Catherine M. McKenzie, Tony Reglinski

Publikováno v: Plants, Vol 10, Iss 11, p 2406 (2021)

This work aims to understand how Vitis vinifera (Chardonnay) vines prioritise the export and distribution of recently fixed photoassimilate between root tissue, fruit, and defence, following the elicitation of a defence response. Jasmonic acid (JA) a

Externí odkaz: https://doaj.org/article/49edf93ebf614710b8db7189e3fdae48

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