Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R. Thödtmann"'
Autor:
R Thödtmann, Josef Thaler, Peter Wohlmuth, Renate Schaberl-Moser, M Jagoditsch, Günther G. Steger, Raimund Jakesz, Hans Rabl, Friedrich Hofbauer, Richard Greil, Michael Gnant, F. Herbst, Hellmut Samonigg, Joerg Tschmelitsch, Walter Schippinger
Publikováno v:
British Journal of Cancer
The purpose of this trial was to investigate the efficacy of adjuvant chemotherapy with 5-fluorouracil (5-FU) and leucovorin (LV) in stage II colon cancer. Patients with stage II colon cancer were randomised to either adjuvant chemotherapy with 5-FU/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b295dcafbb7ffdf14cfa6abbadd8a1
https://doi.org/10.1038/sj.bjc.6604011
https://doi.org/10.1038/sj.bjc.6604011
Autor:
Herlinde Dumez, J. Blatter, A. van Oosterom, Axel-R. Hanauske, R. D. Johnson, R. Thödtmann, H. Depenbrock
Publikováno v:
Journal of Clinical Oncology. 17:3009-3016
PURPOSE: Multitargeted antifolate (MTA; LY231514) has broad preclinical antitumor activity and inhibits a variety of intracellular enzymes involved in the folate pathways. This study was designed to (1) determine the maximum-tolerated dose (MTD), dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5867a8619fc910eeb592d22a4bf88da
https://doi.org/10.1200/jco.1999.17.10.3009
https://doi.org/10.1200/jco.1999.17.10.3009
Autor:
R, Greil, R, Thödtmann
Publikováno v:
Annals of Oncology. 18:ii86-ii88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813d23a82d2d5462ff7adf26bd7458a3
https://doi.org/10.1093/annonc/mdm051
https://doi.org/10.1093/annonc/mdm051
Publikováno v:
Critical Reviews in Neurosurgery. 7:193-197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a5338bd2e12e97fc1825e0d86f67d2f
https://doi.org/10.1007/s003290050025
https://doi.org/10.1007/s003290050025
Autor:
Axel-R. Hanauske, T. Sauter, R. Thödtmann, L. Weissbach, J. Blatter, S. Weinknecht, Ute Ohnmacht
Publikováno v:
Investigational new drugs. 21(3)
Background. Metastatic renal cell carcinoma (RCC) is rising in incidence but remains difficult to treat. This clinical trial evaluated the effects of pemetrexed (multitargeted antifolate, ALIMTA®) for the treatment of metastatic RCC. Patients and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b239e959c91971be18cd52f91d4a57
https://pubmed.ncbi.nlm.nih.gov/14578684
https://pubmed.ncbi.nlm.nih.gov/14578684
Autor:
A.H.G.J Schrijvers, R Thödtmann, Ahmad Awada, Martine Piccart, Axel-R. Hanauske, Jantien Wanders, I.M. von Broen
Publikováno v:
European journal of cancer (Oxford, England : 1990). 39(6)
A single-agent dose-escalating phase I and pharmacokinetic study on the naphthalamide agent, LU 79553, was performed to determine its safety profile, maximum tolerated dose (MTD) and recommended dose for phase II studies. LU 79553 was given intraveno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef01e45715851125083729f4d8ed5c3
https://pubmed.ncbi.nlm.nih.gov/12651198
https://pubmed.ncbi.nlm.nih.gov/12651198
Publikováno v:
Seminars in oncology. 26(2 Suppl 6)
MTA (multitargeted antifolate, LY231514) is a novel antimetabolite resulting from structure/activity studies of the lometrexol-type antifolates. It has been shown to inhibit various enzymes of folate pathways and has broad antitumor activity in a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7fceffd9570a3756084317147a00090
https://pubmed.ncbi.nlm.nih.gov/10598561
https://pubmed.ncbi.nlm.nih.gov/10598561
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(11)
PET using 18F-fluorodeoxyglucose (FDG) is increasingly applied to monitor the response of malignant tumors to radiotherapy and chemotherapy. The aim of this study was to assess the reproducibility of serial FDG PET measurements to define objective cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4055cf9b87d92e78c71850ee3fa681c3
https://pubmed.ncbi.nlm.nih.gov/10565769
https://pubmed.ncbi.nlm.nih.gov/10565769
Autor:
Axel-R. Hanauske, Wolfgang E. Berdel, Ch. Manegold, K. Burk, A. Kaeser-Fröhlich, Andreas Hüttmann, Rassmann I, H.H. Fiebig, R. Thödtmann, M. Mross
Publikováno v:
Investigational new drugs. 16(4)
Background: NK611 is a novel podophyllotoxin derivative. Compared with etoposide, NK611 carries a dimethyl-amino group at the D-glucose moiety. The antitumor activity of NK611 showed to be equal or superior to etoposide in a variety of in vitro and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd52e1399de4652a18a023cb368cac9c
https://pubmed.ncbi.nlm.nih.gov/10426664
https://pubmed.ncbi.nlm.nih.gov/10426664
Autor:
W, Römer, A R, Hanauske, S, Ziegler, R, Thödtmann, W, Weber, C, Fuchs, W, Enne, M, Herz, C, Nerl, M, Garbrecht, M, Schwaiger
Publikováno v:
Blood. 91(12)
Positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) was performed in non-Hodgkin's lymphoma (NHL), which is known to be highly responsive to chemotherapy, but also yields variable treatment results to answer the following questions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::914652cb66e022462720730d86c689b1
https://pubmed.ncbi.nlm.nih.gov/9616140
https://pubmed.ncbi.nlm.nih.gov/9616140