Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R. Tecwyn Williams"'
Publikováno v:
Biochemical Pharmacology. 28:3081-3091
Isolated female rat livers were perfused with a medium containing [ 14 C]LSD (1 mg and 0.13 μCi/g liver) and (+)-tartaric acid (15 mg). After 4.5 hr, the bile collected contained some 44% of the added radioactivity, the perfusate, 20% and the liver
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 3:61-66
Most studies of foreign compound metabolism have been performed in a restricted number of common laboratory animal species. The examination of animals not commonly found in the laboratory may aid in understanding the effects of environmental chemical
Publikováno v:
Journal of Pharmacy and Pharmacology. 26:823-826
Publikováno v:
Biochemical Pharmacology. 28:3093-3101
The qualitative and quantitative aspects of the metabolism and elimination of [14C]LSD in the rat, guinea pig and rhesus monkey have been investigated. Rats given an i.p. dose (1 mg/kg) excreted 73% of the 14C in the faeces, 16% in the urine and 3.4%
Publikováno v:
Biochemical Pharmacology. 24:2225-2232
The metabolism and excretion of orally administered or injected [14C]chlorphentermine has been studied in man, rhesus monkey, marmoset, rabbit, guinea-pig and rat. These species excreted 55–95% of the administered radioactivity in the urine over 5
Publikováno v:
Xenobiotica. 8:253-264
1. The pattern of conjugation in the ferret of 8 arylacetic acids and, for comparison, benzoic acid and 4-nitrobenzoic acid was examined. 2. The arylacetic acids, phenylacetic, 4-chloro- and 4-nitro phenylacetic, alpha-methylphenylacetic (hydratropic
Publikováno v:
Psychological Medicine. 6:35-42
SynopsisIt has been proposed that p-hydroxynorephedrine, a metabolite of amphetamine, is responsible for the tolerance that occurs to this drug. To test this idea, the development of tolerance to amphetamine has been examined in two species, the rat
Publikováno v:
Biochemical Pharmacology. 22:1865-1873
The metabolism and excretion of orally administered or injected n -butyl 4-hydroxy-3,5-di[ 25 I]iodobenzoate has been studied in man, the rhesus, cynomolgus, squirrel and capuchin monkeys and the rat and rabbit. These species excreted most (about 80
Publikováno v:
Biochemical Society Transactions. 2:306-308
Publikováno v:
Biochemical Society Transactions. 5:1033-1035