Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R. Tayfur Tecirlioglu"'
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 46:231-235
Human embryonic stem (hES) cells were originally isolated and maintained on mouse embryonic fibroblast (MEF) feeder layers in the presence of fetal bovine serum (FBS). However, if the hES cells are to be used for therapeutic applications, it is prefe
Autor:
Mark Williamson, Shara Downie, Natasha A. Korfiatis, Andrew J. French, R. Tayfur Tecirlioglu, Melissa A. Cooney, Nancy T. Ruddock, Vanessa Jane Hall
Publikováno v:
Theriogenology. 65:424-440
The efficiency of generating cloned animals following somatic cell nuclear transfer appears to have reached a plateau, despite ongoing research to improve developmental outcomes. A major limitation appears in the restricted nature of the adult/donor
Autor:
Vanessa Jane Hall, Andrew J. French, Nancy T. Ruddock, Prue Shanahan, R. Tayfur Tecirlioglu, Melissa A. Cooney
Publikováno v:
Molecular Reproduction and Development. 72:471-482
The nuclear lamina is a complex meshwork of nuclear lamin filaments that lies on the interface of the nuclear envelope and chromatin and is important for cell maintenance, nucleoskeleton support, chromatin remodeling, and protein recruitment to the i
Autor:
Andrew J. French, Melissa A. Cooney, Natasha A. Korfiatis, R. Tayfur Tecirlioglu, Katrina J. Wilson, Nancy T. Ruddock
Publikováno v:
Biology of Reproduction. 70:1131-1135
While the expression and epigenetic differences of imprinted genes have been extensively characterized in the mouse and human, little is known about imprinted genes in livestock species. In the current study, eight genes that are imprinted in the hum
Publikováno v:
Cellular reprogramming. 12(5)
Embryonic stem cells (ESCs) have the potential to reprogram somatic cells into ESC-like cells through cell fusion. In the present study, the potential of human (h)ESC cytoplasts and karyoplasts to reprogram human hepatocytes was evaluated. Green fluo
Mitochondrial DNA transmission and transcription after somatic cell fusion to one or more cytoplasts
Autor:
Emma J. Bowles, Michael K. Holland, Andrew J. French, Justin C. St. John, R. Tayfur Tecirlioglu
Publikováno v:
Stem cells (Dayton, Ohio). 26(3)
Following fertilization, mitochondrial DNA is inherited from the oocyte and transmitted homoplasmically. However, following nuclear transfer, mitochondrial DNA can be transmitted from both the donor cell and recipient oocyte, resulting in a state of
Autor:
Michael K. Holland, Cesare Galli, Irina Lagutina, Nancy T D' Cruz, R. Tayfur Tecirlioglu, Katrina J. Wilson, Melissa A. Cooney, Andrew J. French
Altered patterns of gene expression and the imprinted status of genes have a profound effect on cell physiology and can markedly alter embryonic and fetal development. Failure to maintain correct imprinting patterns can lead to abnormal growth and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163032f532256e35202dc084097b5bbe
http://hdl.handle.net/11585/70556
http://hdl.handle.net/11585/70556
Publikováno v:
Methods in Molecular Biology ISBN: 9781588292803
Apart from the biological and ethical problems, technical difficulties also hamper the improvement and widespread application of somatic cell nuclear transfer (NT). Recently introduced zona-free procedures may offer a solution for the latter problem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cd30480e96f2cd15cac95ae98e211e
https://doi.org/10.1385/1-59745-154-1:183
https://doi.org/10.1385/1-59745-154-1:183
Autor:
Shara Downie, Natasha A. Korfiatis, Renee Hodgson, Mark Williamson, David B. Galloway, Melissa A. Cooney, Andrew J. French, R. Tayfur Tecirlioglu
Publikováno v:
Theriogenology. 65(9)
In this comparative study, reproductive parameters and semen characteristics of cloned bulls (n = 3) derived from somatic cell nuclear transfer (SCNT) were compared to their original cell donor Holstein-Friesian (n = 2) bulls from the same enterprise
Autor:
Shara Downie, Gábor Vajta, Michael K. Holland, Alan O Trounson, Natasha A. Korfiatis, Melissa A. Cooney, Andrew J. French, Nancy T. Ruddock, Renee Hodgson, Ian Lewis, R. Tayfur Tecirlioglu
Publikováno v:
Tecirlioglu, R T, Cooney, M A, Lewis, I M, Korfiatis, N A, Hodgson, R, Ruddock, N T, Vajta, G, Downie, S, Trounson, A O, Holland, M K & French, A J 2005, ' Comparison of two approaches to nuclear transfer in the bovine: hand-made cloning with modifications and the conventional nuclear transfer ', Reproduction, Fertility and Development, vol. 17, no. 5, pp. 573-585 . https://doi.org/10.1071/RD04122
The aim of the present study was to compare the in vitro and in vivo developmental competence of hand-made cloning (HMC) embryos with the conventional nuclear transfer (NT) method using five somatic cell lines and in vitro-fertilised (IVF; control) e