mRNA‐Engineered CD5‐CAR‐γδT^CD5‐ Cells for the Immunotherapy of T‐Cell Acute Lymphoblastic Leukemia.

Autor: Zhu, Zhixiong¹ (AUTHOR), Li, Hexian¹ (AUTHOR), Lu, Qizhong¹ (AUTHOR), Zhang, Zongliang¹ (AUTHOR), Li, Jia¹ (AUTHOR), Wang, Zeng¹ (AUTHOR), Yang, Nian¹ (AUTHOR), Yu, Zhengyu² (AUTHOR), Yang, Chen¹ (AUTHOR), Chen, Yongdong¹ (AUTHOR), Lu, Huaqing¹ (AUTHOR), Wang, Wei¹ (AUTHOR), Niu, Ting² (AUTHOR) niuting@wchscu.cn, Nie, Chunlai¹ (AUTHOR) niecl1022@scu.edu.cn, Tong, Aiping^1,3 (AUTHOR) aipingtong@scu.edu.cn

Publikováno v: Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-13. 13p.

Reduction in susceptibility to natural killer cell-mediated lysis of human FO-1 melanoma cells after induction of HLA class I antigen expression by transfection with B2m gene

Autor: Soldano Ferrone, Maresa Altomonte, R A Zeff, Michele Maio, R. Tatake

Publikováno v: Journal of Clinical Investigation. 88:282-289

Induction of HLA class I antigens on cultured melanoma cells FO-1 after transfection with a human or a mouse B2m gene was associated with a statistically significant reduction in their susceptibility to natural killer (NK) cell-mediated lysis. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69993138a0f0da502f56331427a306a4
https://doi.org/10.1172/jci115289

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression

Autor: Zhigang Wang, R A Zeff, Soldano Ferrone, R. Tatake, Yan Cao, C. M. D'urso

Publikováno v: The Journal of clinical investigation. 87(1)

The melanoma cell line FO-1 does not express HLA class I antigens and does not acquire them on the cell surface after incubation with IFN-gamma. Immunochemical studies showed that FO-1 cells synthesize HLA class I heavy chain, but do not synthesize b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996c00688060db960734ce53c6ec452d
https://pubmed.ncbi.nlm.nih.gov/1898655

CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models.

Autor: Timpanaro, Andrea^1,2,3 (AUTHOR), Piccand, Caroline^1,2,3 (AUTHOR), Dzhumashev, Dzhangar^1,2,3 (AUTHOR), Anton-Joseph, Stenija^1,2,3 (AUTHOR), Robbi, Andrea^1,2 (AUTHOR), Moser, Janine^1,2 (AUTHOR), Rössler, Jochen^1,2 (AUTHOR), Bernasconi, Michele^1,2 (AUTHOR) michele.bernasconi@unibe.ch

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 11/4/2023, Vol. 42 Issue 1, p1-30. 30p.

A novel CAR-T cell product targeting CD74 is an effective therapeutic approach in preclinical mantle cell lymphoma models.

Autor: Chan, Wing Keung¹ (AUTHOR), Williams, Jessica¹ (AUTHOR), Sorathia, Kinnari¹ (AUTHOR), Pray, Betsy¹ (AUTHOR), Abusaleh, Kaled¹ (AUTHOR), Bian, Zehua¹ (AUTHOR), Sharma, Archisha¹ (AUTHOR), Hout, Ian¹ (AUTHOR), Nishat, Shamama¹ (AUTHOR), Hanel, Walter¹ (AUTHOR), Sloan, Shelby L.¹ (AUTHOR), Yasin, Aneeq¹ (AUTHOR), Denlinger, Nathan¹ (AUTHOR), Zhang, Xiaoli² (AUTHOR), Muthusamy, Natarajan¹ (AUTHOR), Vasu, Sumithira¹ (AUTHOR), de Lima, Marcos¹ (AUTHOR), Yang, Yiping¹ (AUTHOR), Baiocchi, Robert¹ (AUTHOR), Alinari, Lapo¹ (AUTHOR) lapo.alinari@osumc.edu

Publikováno v: Experimental Hematology & Oncology. 9/22/2023, Vol. 12 Issue 1, p1-15. 15p.