Zobrazeno 1 - 10
of 816
pro vyhledávání: '"R. Tannenbaum"'
Autor:
Corey Weistuch, Kevin A. Murgas, Jiening Zhu, Larry Norton, Ken A. Dill, Allen R. Tannenbaum, Joseph O. Deasy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cancer transcriptional patterns reflect both unique features and shared hallmarks across diverse cancer types, but whether differences in these patterns are sufficient to characterize the full breadth of tumor phenotype heterogeneity remains
Externí odkaz:
https://doaj.org/article/e1680c5d61d74dc0b12a00afe279b9bc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Melanoma response to immune-modulating therapy remains incompletely characterized at the molecular level. In this study, we assess melanoma immunotherapy response using a multi-scale network approach to identify gene modules with coordinated
Externí odkaz:
https://doaj.org/article/04e0b227a7aa4192af731a68187e16e2
Autor:
Rena Elkin, Jung Hun Oh, Filemon Dela Cruz, Larry Norton, Joseph O. Deasy, Andrew L. Kung, Allen R. Tannenbaum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Network properties account for the complex relationship between genes, making it easier to identify complex patterns in their interactions. In this work, we leveraged these network properties for dual purposes. First, we clustered pediatric
Externí odkaz:
https://doaj.org/article/1a3a594da4ab4acdaeb47f73b4300bb7
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract As a generalization of the optimal mass transport (OMT) approach of Benamou and Brenier’s, the regularized optimal mass transport (rOMT) formulates a transport problem from an initial mass configuration to another with the optimality defin
Externí odkaz:
https://doaj.org/article/66188616cc9c4400bcc9037b953193c1
Autor:
Alexander Y. Andreyev, Hongmei Yang, Paschalis‐Thomas Doulias, Nima Dolatabadi, Xu Zhang, Melissa Luevanos, Mayra Blanco, Christine Baal, Ivan Putra, Tomohiro Nakamura, Harry Ischiropoulos, Steven R. Tannenbaum, Stuart A. Lipton
Publikováno v:
Advanced Science, Vol 11, Iss 12, Pp n/a-n/a (2024)
Abstract In Alzheimer's disease (AD), dysfunctional mitochondrial metabolism is associated with synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for this relationship, however, is still lacking. Here, comparin
Externí odkaz:
https://doaj.org/article/4b2d8ce6444d4cbcb0c378825ef1c175
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Compositional systems, represented as parts of some whole, are ubiquitous. They encompass the abundances of proteins in a cell, the distribution of organisms in nature, and the stoichiometry of the most basic chemical reactions. T
Externí odkaz:
https://doaj.org/article/fe297b185b1b4653a0377abbca1488fd
Autor:
Rena Elkin, Jung Hun Oh, Ying L. Liu, Pier Selenica, Britta Weigelt, Jorge S. Reis-Filho, Dmitriy Zamarin, Joseph O. Deasy, Larry Norton, Arnold J. Levine, Allen R. Tannenbaum
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Network analysis methods can potentially quantify cancer aberrations in gene networks without introducing fitted parameters or variable selection. A new network curvature-based method is introduced to provide an integrated measure of variabi
Externí odkaz:
https://doaj.org/article/14677a3e0f704e37a93284a2df2fb8ea
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
In this paper, we present a network-based clustering method, called vector Wasserstein clustering (vWCluster), based on the vector-valued Wasserstein distance derived from optimal mass transport (OMT) theory. This approach allows for the natural inte
Externí odkaz:
https://doaj.org/article/5bb18def619e41229038fe6c6cad090a
Autor:
Anh Phong Tran, Christopher J. Tralie, José Reyes, Caroline Moosmüller, Zehor Belkhatir, Ioannis G. Kevrekidis, Arnold J. Levine, Joseph O. Deasy, Allen R. Tannenbaum
Publikováno v:
Cell Death & Differentiation. 30:660-672
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77d583f2f149ea2ba8632aca9b7965b5
https://doi.org/10.1038/s41418-022-01069-x
https://doi.org/10.1038/s41418-022-01069-x
Publikováno v:
Virtual Reality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb4e98600024b34040edd462e13c0dc
https://doi.org/10.1007/s10055-023-00760-9
https://doi.org/10.1007/s10055-023-00760-9